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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mol Cancer Res. 2019 Sep 30;17(12):2410–2421. doi: 10.1158/1541-7786.MCR-19-0221

Figure 3.

Figure 3.

Mutational signatures called using Bayesian NMF in the entire canine hemangiosarcoma cohort, showing the count of mutations (y-axis) in each trinucleotide context (x-axis). This analysis reveals the COSMIC SBS1 aging signature (top), and a faint novel signature (bottom).