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Methods comparison: relationship between the SNP buffering epistatic effects estimated via the bivariate REML analyses and the mechanical heuristic (A and C), and between the bivariate REML analyses and the approximation based on the regression of residuals on GEBV (B and D) for the Brahman (A and B) and Tropical Composite (C and D) populations. Highlighted red are the significant SNP (P < 0.0001) according to REML.
