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. 2019 Nov 30;105(4):1157–1168. doi: 10.1210/clinem/dgz241

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© Endocrine Society 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

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Figure 4. — Hepatitis C virus (HCV) infection increased the production of major cytokines at the protein levels in human thyrocytes compared to mock-infected cells.

Protein levels: Concentration of protein levels (pg/mL) in supernatant from cells in culture. Human thyroid cell line ML-1 cells: (A1) CXCL8, (B1) IL-6, and (C1) TNF-α; Human hepatocyte cell line Huh7.5 cells: (D1) CXCL8, (E1) IL-6, (F1) TNF-α.

Results are presented as mean [standard error of the mean]. ***P < 0.001. mRNA level: relative expression of mRNA by RT-qPCR corrected to GAPDH. ML-1 cells: (A2) CXCL8, (B2) IL-6, and (C2) TNF-α; Huh7.5 cells: (D2) CXCL8, (E2) IL-6, (F2) TNF-α. Results are presented in mean+/-SEM. *P < 0.05. Abbreviations: CXCL8, Chemokine 8; IL-6, Interleukin 6; TNF-α, Tummor necrosis alpha.