Table 2. Univariate logistic regression analysis of potential risk factor in predicting CMV reactivation in CMV seropositive kidney transplant recipients.
Univariate Logistic Regression (n = 117) | |||
---|---|---|---|
Variable | n (%) | p | Odds ratio (95% CI) |
Older age cohort | 63 (53.85) | 0.003 | 1.31 (1.10,1.56) |
Sex female | 50 (42.74) | 0.855 | 0.98 (0.82,1.18) |
DM | 42 (35.90) | 0.0144 | 1.26 (1.05, 1.51) |
Prior transplant | 21 (17.95) | 0.0319 | 0.78 (0.82,0.98) |
CMV seropositive donor | 86 (73.50) | 0.589 | 1.06 (0.86,1.30) |
No induction (=steroids only) | 18 (15.38) | 0.404 | 0.90 (0.70,1.15) |
Basiliximab induction | 61 (52.14) | 0.023 | 1.23 (1.03,1.47) |
Rejection | 15 (12.8) | 0.638 | 0.94 (0.72, 1.23) |
Augmented I/S | 14 (11.97) | 0.471 | 0.90 (0.69, 1.20) |
BKV | 31 (27.19) | 0.724 | 0.96 (0.79, 1.18) |
Use of CMV directed ppx for at least 30 days (GCV/VGCV) | 59 (50.43) | 0.411 | 1.08(0.90,1.29) |
Bacteremia | 17 (14.30) | 0.99 | 1.00 (0.77,1.29) |
Pneumonia | 13 (11.11) | 0.43 | 1.12 (0.84,1.49) |
Urinary tract infection | 51 (43.59) | 0.729 | 1.03 (0.86, 1.24) |
Admission for infection [patient level] ¥ | 52 (44.44) | 0.382 | 1.08 (0.91, 1.30) |
Surgery [patient level] ¥¥ | 30 (25.64) | 0.577 | 1.06 (0.86, 1.30) |
Ambulation before transplant (independent/needs assistance/dependent) ¥¥¥ | 99 (84.62) | 0.365 | 0.92 (0.78, 1.10) |
52 patients with at least one admission for infection.
30 patients with at least 1 re-operation/surgery (39 total episodes).
Missing in 2 cases. DM: diabetes mellitus; I/S: immunosuppression; BKV: BK polyomavirus; ppx: prophylaxis; GCV: ganciclovir; VGCV: valganciclovir.