Table 4. Univariate logistic regression analysis of potential risk factor in predicting CMV reactivation in CMV seropositive kidney transplant recipients that did not receive thymoglobulin.
Univariate Logistic Regression (n=77) | |||||
---|---|---|---|---|---|
Variable | n (%) | Any CMV PCR | CMV PCR 450+ IU/ml¥ | ||
p | Odds ratio (95% CI) | p | Odds ratio (95% CI) | ||
Older age cohort | 45 (58.44) | 0.0008 | 1.44 (1.17,1.76) | 0.174 | 1.17 (0.93, 1.47) |
Sex female | 26 (33.77) | 0.954 | 1.01 (0.80, 1.27) | 0.688 | 1.05 (0.83, 1.33) |
DM | 32 (42.86) | 0.0413 | 1.25 (1.01, 1.55) | 0.163 | 1.18 (0.94,1.48) |
Prior transplant | 8 (10.39) | 0.012 | 0.64 (0.46,0.90) | 0.0407 | 0.68 (0.48, 0.98) |
CMV seropositive donor | 49 (66.64) | 0.117 | 1.20 (0.96, 1.49) | 0.327 | 1.12 (0.89, 1.42) |
No induction (=steroids only) | 18 (23.38) | 0.133 | 0.822 (0.64, 1.06) | 0.452 | 0.90 (0.69, 1.18) |
Basiliximab induction | 59 (76.62) | 0.133 | 1.22 (0.95, 1.56) | 0.452 | 1.11 (0.85, 1.45) |
Rejection $$ | 9 (11.69) | 0.537 | 0.90 (0.64, 1.26) | 0.884 | 0.97 (0.69, 1.38) |
Augmented I/S | 9 (11.69) | 0.356 | 0.85 (0.60, 1.20) | 0.585 | 0.90 (0.62, 1.30) |
BKV | 20 (25.97) | 0.279 | 1.15 (0.90, 1.46) | 0.172 | 1.20 (0.93, 1.54) |
Use of CMV directed ppx for at least 30 days (GCV/VGCV) | 13 (15.58) | 0.782 | 0.96 (0.72, 1.28) | 0.963 | 0.99 (0.73, 1.34) |
Bacteremia | 15 (19.48) | 0.66 | 0.94 (0.72, 1.23) | 0.565 | 0.92 (0.69, 1.22) |
Pneumonia | 12 (15.58) | 0.893 | 1.02 (0.76, 1.37) | 0.388 | 1.15 (0.84, 1.56) |
Admission for infection [patient level] | 36 (46.75) | 0.769 | 1.03 (0.83, 1.28) | 0.327 | 1.12 (0.89, 1.40) |
Surgery [patient level] | 20 (25.97) | 0.597 | 0.94 (0.73, 1.20) | 0.739 | 1.04 (0.81, 1.35) |
n=52
Nine patients with rejection, 2 of them had 2 episodes.