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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Eur J Clin Microbiol Infect Dis. 2019 Nov 22;39(3):455–463. doi: 10.1007/s10096-019-03744-3

Table 4. Univariate logistic regression analysis of potential risk factor in predicting CMV reactivation in CMV seropositive kidney transplant recipients that did not receive thymoglobulin.

DM: diabetes mellitus; I/S: immunosuppression; BKV: BK polyomavirus; ppx: prophylaxis; GCV: ganciclovir; VGCV: valganciclovir.

Univariate Logistic Regression (n=77)
Variable n (%) Any CMV PCR CMV PCR 450+ IU/ml¥
p Odds ratio (95% CI) p Odds ratio (95% CI)
Older age cohort 45 (58.44) 0.0008 1.44 (1.17,1.76) 0.174 1.17 (0.93, 1.47)
Sex female 26 (33.77) 0.954 1.01 (0.80, 1.27) 0.688 1.05 (0.83, 1.33)
DM 32 (42.86) 0.0413 1.25 (1.01, 1.55) 0.163 1.18 (0.94,1.48)
Prior transplant 8 (10.39) 0.012 0.64 (0.46,0.90) 0.0407 0.68 (0.48, 0.98)
CMV seropositive donor 49 (66.64) 0.117 1.20 (0.96, 1.49) 0.327 1.12 (0.89, 1.42)
No induction (=steroids only) 18 (23.38) 0.133 0.822 (0.64, 1.06) 0.452 0.90 (0.69, 1.18)
Basiliximab induction 59 (76.62) 0.133 1.22 (0.95, 1.56) 0.452 1.11 (0.85, 1.45)
Rejection $$ 9 (11.69) 0.537 0.90 (0.64, 1.26) 0.884 0.97 (0.69, 1.38)
Augmented I/S 9 (11.69) 0.356 0.85 (0.60, 1.20) 0.585 0.90 (0.62, 1.30)
BKV 20 (25.97) 0.279 1.15 (0.90, 1.46) 0.172 1.20 (0.93, 1.54)
Use of CMV directed ppx for at least 30 days (GCV/VGCV) 13 (15.58) 0.782 0.96 (0.72, 1.28) 0.963 0.99 (0.73, 1.34)
Bacteremia 15 (19.48) 0.66 0.94 (0.72, 1.23) 0.565 0.92 (0.69, 1.22)
Pneumonia 12 (15.58) 0.893 1.02 (0.76, 1.37) 0.388 1.15 (0.84, 1.56)
Admission for infection [patient level] 36 (46.75) 0.769 1.03 (0.83, 1.28) 0.327 1.12 (0.89, 1.40)
Surgery [patient level] 20 (25.97) 0.597 0.94 (0.73, 1.20) 0.739 1.04 (0.81, 1.35)
¥

n=52

$$

Nine patients with rejection, 2 of them had 2 episodes.