TABLE 1.
Serological diagnosis of melioidosis
| Serologic test | % sensitivity (reference) | % specificity (reference) | Country(ies) |
|---|---|---|---|
| Serum indirect hemagglutination assay (IHA)a | 51 (212)–95 (213) | 74 (213)–97 (213) | Australia and Thailand |
| Inactivated cell suspension IgG ELISA | 90 (218) | 99 (218) | Australia |
| IgM ICT test (PanBio) | 72 (220)–93 (219) | 69 (221)–95 (219) | Australia |
| IgG ICT test (PanBio) | 51 (220)–100 (219) | 90 (221)–97 (220) | Australia |
| Recombinant Hcp1 ELISA | 93.7 (225) | 100 (225) | Malaysia |
| Recombinant Hcp1 ICT | 88.3 (227) | 86.1 (227) | Thailand |
| Recombinant GroEL ELISA | 92.1 (210) | 88.3 (210) | Thailand |
| Combination of IHA and IgM ELISA | 100 (229) | 95.4 (229) | Thailand |
a
Cutoff values of ≥1:40 to ≥1:320 were used in studies, with results depending on cutoff value used.