Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: J Struct Biol. 2020 Feb 4;210(1):107474. doi: 10.1016/j.jsb.2020.107474

Fig. 4. Extracellular vesicle post-isolation concentration and morphology.

Fig. 4.

(A) Mean overall particle concentration from nanoparticle tracking analysis (NTA) of EVs shed and/or secreted from MCF10A HAS3 and control cells. Error bars represent standard error of the mean from three individual measurements for each cell line. (B-D) Cryo-TEM of frozen-hydrated vesicles post-isolation from HAS3 cells shows heterogeneity in vesicle shape and size. Additionally, larger HAS3 vesicles have prominent surface structure (B-C, arrows), while smaller vesicles have either less or no such surface structure (D).