Table 2.
Comparison of Fontan patients with and without muscle wasting in the sarcopenic range based on muscle measurements at L3
| Variable | No sarcopenia | N | Sarcopenia | N | P value |
|---|---|---|---|---|---|
| Age (y), mean ± SD | 24.9 ± 7.9 | 36 | 30.9 ± 5.9 | 4 | 0.150 |
| Age at Fontan operation (y), mean ± SD | 4.3 ± 3.8 | 35 | 5.3 ± 3.5 | 4 | 0.602 |
| Saturation (%), mean ± SD | 92.4 ± 4.3 | 35 | 94.3 ± 2.9 | 4 | 0.419 |
| Fontan type | 36 | 4 | 0.446 | ||
| Atriopulmonary, n (%) | 7 (19.4) | 0 | |||
| Lateral tunnel, n (%) | 20 (55.6) | 2 (50) | |||
| Extracardiac conduit, n (%) | 9 (25) | 2 (50) | |||
| Peak VO2 (mL/kg/min), mean ± SD | 23.5 ± 7.0 | 34 | 21.7 ± 5.1 | 4 | 0.620 |
| Peak O2 pulse (mL/beat), mean ± SD | 10.9 ± 3.3 | 31 | 11.7 ± 5.0 | 4 | 0.685 |
| Workload (watts), mean ± SD | 138 ± 42 | 32 | 109 ± 33 | 4 | 0.195 |
Sarcopenic range is defined as an SMI at L3 of < 45.4 cm2/m2 for men and < 34.4 cm2/m2 for women based on Derstine et al.20
SD, standard deviation; VO2, oxygen consumption.