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. 2020 Jan 10;20(1):17–22. doi: 10.1007/s40268-019-00292-1

Table 2.

Fosphenytoin dosing information

Dosing Patients
Fosphenytoin indication (n = 51)
 Seizures 47 (92.2)
 Home medication 5 (9.8)
 Prophylaxis 4 (7.8)
Free phenytoin target goal (n = 51)
 1.0–2.0 mcg/mL 4 (7.8)
 1.5–2.0 mcg/mL 13 (25.5)
 1.5–2.5 mcg/mL 11 (21.6)
 2.0–2.5 mcg/mL 7 (13.7)
 Unspecified 16 (31.4)
Initial loading dose (mg/kg) 18.2 ± 4.4
Reloading dose calculation strategy (n = 152)
 Equation 49 (32.2)
 Equation without Vd or salt formulation 67 (44.1)
 Provider preference 36 (23.7)

Data are presented as mean ± standard deviation or N (%) unless otherwise indicated

Vd volume of distribution