Table 2.
Dosing | Patients |
---|---|
Fosphenytoin indication (n = 51) | |
Seizures | 47 (92.2) |
Home medication | 5 (9.8) |
Prophylaxis | 4 (7.8) |
Free phenytoin target goal (n = 51) | |
1.0–2.0 mcg/mL | 4 (7.8) |
1.5–2.0 mcg/mL | 13 (25.5) |
1.5–2.5 mcg/mL | 11 (21.6) |
2.0–2.5 mcg/mL | 7 (13.7) |
Unspecified | 16 (31.4) |
Initial loading dose (mg/kg) | 18.2 ± 4.4 |
Reloading dose calculation strategy (n = 152) | |
Equation | 49 (32.2) |
Equation without Vd or salt formulation | 67 (44.1) |
Provider preference | 36 (23.7) |
Data are presented as mean ± standard deviation or N (%) unless otherwise indicated
Vd volume of distribution