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. 2020 Mar 6;10:315. doi: 10.3389/fonc.2020.00315

Table 2.

Performance of previously published prognostic biomarker in OSeac.

Gene symbol Literature data OSeac data
n P-value Prognostic value References HR (95% CI) P-value Survival Validation results
DKK3 116 <0.0500 Poor (11) 2.8012 (1.2033–6.5212) 0.0169 OS
TXNIP 228 0.0020 Good (12) 0.3698 (0.1424–0.9538) 0.0396 OS
CDO1 38 0.0360 Poor (13) 3.3329 (1.5175–7.3202) 0.0027 OS

OS, overall survival; HR, hazard ratio; CI, confidence interval; DKK3, dickkopf WNT signaling pathway inhibitor 3; CDO1, cysteine dioxygenase type 1; TXNIP, thioredoxin interacting protein.