Table 2.
List of differentially methylated regions between long-term meditators and controls located in subtelomeric regions.
Gene alias | Chr | DMR-start | DMR-end | no.probes | p-value | beta.diff | Genomic Location |
---|---|---|---|---|---|---|---|
C8orf73/MROH6 | chr8 | 144654887 | 144655484 | 4 | 0,002101627 | −0,057729475 | 1stExon,5′UTR,TSS200,TSS1500 |
ERICH1-AS1 | chr8 | 709576 | 709692 | 2 | 0,036605753 | −0,059338436 | |
GPR31 | chr6 | 167571172 | 167571803 | 5 | 0,023259942 | −0,07099427 | 1stExon,TSS200,TSS1500 |
KBTBD11 | chr8 | 1954777 | 1955196 | 4 | 3,90054E-08 | −0,053 | 3′UTR |
MADCAM1 | chr19 | 495355 | 495737 | 2 | 0,001456746 | −0,081370984 | TSS1500 |
MLPH | chr2 | 238406108 | 238406478 | 3 | 0,003007912 | −0,056124149 | Body |
MYL5,MFSD7 | chr4 | 675137 | 675827 | 3 | 0,008481849 | 0,126013355 | Body |
PRR25 | chr16 | 857454 | 857863 | 3 | 0,036715428 | 0,106034484 | Body |
RPS6KA2 | chr6 | 166876490 | 166877038 | 7 | 0,000731957 | −0,064536785 | Body |
RPS6KA2 | chr6 | 167070053 | 167070616 | 3 | 0,009173941 | 0,081025691 | Body |
RUFY1 | chr5 | 178986131 | 178986728 | 7 | 0,029542821 | −0,063294921 | TSS1500,Body,TSS200 |
SERPINB9 | chr6 | 2891973 | 2892050 | 2 | 0,00012719 | 0,061725435 | Body |
SRXN1 | chr20 | 633418 | 634604 | 4 | 0,004924204 | −0,062058469 | Body,TSS1500 |
UNCX | chr7 | 1266180 | 1267228 | 4 | 0,000393945 | −0,114311707 | |
Intergenic | chr4 | 1514317 | 1514621 | 2 | 0,008962804 | −0,086216947 |
NA = not applicable, Chr = Chromosome, DMR = differentially methylated region, DMR-start = coordinates of the beginning of each DMR annotated by UCSC hg19 build, DMR-end = coordinates of the end of each DMR annotated by UCSC hg19 build, no.probes = total number of differentially methylated probes within each DMR, beta.diff = difference in average methylation between mindfulness-practitioners and controls for each DMR, UTR = untranslated region, TSS = transcription start site.