Table 3.
Explanatory power of gene methylation on the length of long telomeres according to group.
Meditators | Non- Meditators | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Md | SD | r | R2 | Beta | R2y.12 | Md | SD | r | R2 | Beta | R2y.12 | |
0.15 | 0.91*** | |||||||||||
Age | −0.39 | −0.93*** | ||||||||||
UNCX | 0.592 | 0.135 | −0.03 | <0.01 | 0.03 | 0.706 | 0.050 | −0.28 | 0.08 | −0.11 | ||
0.41* | 0.90*** | |||||||||||
Age | −0.38 | −0.95*** | ||||||||||
NA | 0.537 | 0.067 | −0.51* | 0.26* | −0.51* | 0.623 | 0.076 | 0.14 | 0.02 | 0.01 | ||
0.17 | 0.90*** | |||||||||||
Age | −0.46 | −0.94*** | ||||||||||
MADCAM1 | 0.414 | 0.064 | 0.03 | <0.01 | −0.18 | 0.496 | 0.060 | 0.37 | 0.14 | 0.04 | ||
0.45* | 0.92*** | |||||||||||
Age | −0.33 | −0.94*** | ||||||||||
GPR31 | 0.480 | 0.061 | 0.58* | 0.34* | 0.55* | 0.551 | 0.072 | 0.19 | 0.04 | 0.14 | ||
0.15 | 0.90*** | |||||||||||
Age | −0.39 | −0.95*** | ||||||||||
RPS6KA2 | 0.801 | 0.066 | 0.03 | <0.01 | 0.05 | 0.720 | 0.053 | −0.02 | <0.01 | −0.05 | ||
0.24 | 0.90*** | |||||||||||
Age | −0.40 | −0.95*** | ||||||||||
SFXN1 | 0.536 | 0.050 | 0.29 | 0.08 | 0.30 | 0.596 | 0.060 | 0.25 | 0.06 | 0.01 | ||
0.19 | 0.90*** | |||||||||||
Age | −0.28 | −0.94*** | ||||||||||
SRXN1 | 0.571 | 0.048 | 0.36 | 0.13 | 0.23 | 0.633 | 0.038 | −0.15 | 0.02 | −0.03 | ||
0.23 | 0.92*** | |||||||||||
Age | −0.42 | −0.96*** | ||||||||||
ERICH1_AS1 | 0.668 | 0.065 | 0.25 | 0.06 | 0.29 | 0.727 | 0.040 | 0.04 | <0.01 | 0.13 | ||
0.15 | 0.90*** | |||||||||||
Age | −0.39 | −0.95*** | ||||||||||
C8orf73 | 0.252 | 0.043 | −0.06 | <0.01 | −0.06 | 0.310 | 0.070 | 0.08 | 0.01 | −0.01 | ||
0.16 | 0.90*** | |||||||||||
Age | −0.34 | −0.95*** | ||||||||||
MLPH | 0.725 | 0.043 | 0.25 | 0.06 | 0.11 | 0.782 | 0.028 | −0.29 | 0.08 | 0.01 | ||
0.20 | 0.90*** | |||||||||||
Age | −0.43 | −0.95*** | ||||||||||
KBTBD11 | 0.306 | 0.064 | 0.14 | 0.02 | 0.23 | 0.340 | 0.055 | 0.29 | 0.08 | −0.01 | ||
0.40* | 0.90*** | |||||||||||
Age | <0.01 | −0.95*** | ||||||||||
SERPINB9 | 0.790 | 0.042 | −0.64** | 0.40** | −0.64* | 0.728 | 0.038 | −0.07 | 0.01 | −0.02 | ||
0.27 | 0.90*** | |||||||||||
Age | −0.31 | −0.95*** | ||||||||||
SSTR5 | 0.577 | 0.057 | −0.43 | 0.18 | −0.36 | 0.525 | 0.027 | 0.01 | <0.01 | 0.03 | ||
0.16 | 0.91*** | |||||||||||
Age | −0.32 | −0.96*** | ||||||||||
MYL5 | 0.295 | 0.174 | −0.29 | 0.08 | −0.13 | 0.169 | 0.105 | 0.06 | <0.01 | −0.10 |
Md = mean. SD = standard deviation. r = Pearson’s raw correlation between telomere length and gene methylation. R2 = bivariate determination coefficient (dependent variable: telomere length; independent variable: genes methylation). R2y.12 = multiple determination coefficient (dependent variable: telomere length; independent variables: age and gene methylation). Beta = standardized slope when using multiple regression models. *p < 0.05. **p < 0.01. ***p < 0.001.