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. 2020 Mar 6;11:173. doi: 10.3389/fphar.2020.00173

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Copyright © 2020 Bai, Bao, Jiang, Ge, He, Zhao, Zhang, Dong, Hua, Yang, Mo and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bar chart (A) and Hierarchical clustering (B) of DEMs in Model group and JTXK-treated group. (A) The abscissa of bar chart is log2(fold change) of DEMs. Red bars represent miRNAs significantly increased in JTXK-treated group, while the green bars represent the downregulated miRNAs (only the top 20 was illustrated). (B) Hierarchical clustering was generated according to the expression levels of miRNA, and a total of six samples were taken from either J group (JTXK-treated group) or M group (Model group). Green, significantly decreased; Red significantly increased.