Figure 1.

A) Liver core biopsy shows a poorly differentiated carcinoma with granular to clear cytoplasm, increased N/C ratio, and arranged in solid and thickened trabecular growth pattern. Abundant apoptosis and brisk mitosis were seen. The sinusoid is congested. The tumor cell is immunoreactive to Glypican 3 and Arginase 1 (not shown), supporting poorly differentiated hepatocellular carcinoma. (B) Pleural fluid showed atypical cells, morphologically identical to that is seen in liver core biopsy, consistent with hepatocellular carcinoma.