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A Schematic to Illustrate the Mathematical Computation of Markov Trace in Excel.
| Sorafenib (Intervention) arm – How to implement in excel | ||||||
|---|---|---|---|---|---|---|
| A | B | C | D | E | F | |
| 1 | Cycle | PFS | PD | Death from disease | All-cause mortality | Check |
| 2 | 1 | 1000 | 0 | 0 | 0 | =Sum (B2:E2) |
| 3 | 2 | =B2*(1-sPFSPD-sPFSD) | =(B2*sPFSPD) +(C2*(1-sPDD)) | =C2*sPDD | =B2*sPFSD | = Sum (B3:E3) |
| 4 | 3 | =B3*(1-sPFSPD-sPFSD) | =(B3*sPFSPD) +(C3*(1-sPDD)) | =C3*sPDD | =B3*sPFSD | =Sum (B4:E4) |
PFS, progression-free state; PD, progressive disease.
