Table 7.
Effect of 0.8 ppm/2 h/2times/5days on C57BL/6 J mice.
Mice No./genotype | Plasma 4HNE level(A.U) |
OB 4HNE level(A.U) |
OB CYP1A1 level(A.U) |
OB proteins level(A.U) |
Decrease in B.W % * | ||||
---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||
Control 8 (WT) | 100 | 18.1 | 100 | 32.1 | 100 | 48.4 | 100 | 42.0 | – |
7 (GFP) | 112.3 | 22.4 | 105.1 | 38.6 | Abs. | Abs. | 108.3 | 32.8 | Yes (24.1) |
*: Indicates P< 0.05.
SD: Standard deviation.
B.W: body weight.
OB: olfactory bulb.
CYP1A1: Cytochrome P450, family 1, subfamily A, polypeptide 1.
WT: Wild Type.
No.: Number.
GFP: Green Florescent Protein.
Abs.: Absent.
ppm: parts per million.
h: hour.
min: minute.
O3: ozone.
4HNE: 4-hydroxynonenal.
%: percentage.
Control: non-O3 exposed.