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. 2020 Feb 15;16:289–301. doi: 10.1016/j.omto.2020.02.001

Figure 5.

Figure 5

NK Ligand Expression following Ad5 Adenovirus Infection

(A) TOV21G were infected with dl922-947 in triplicate (MOI 10, 48 h). Expression of evaluation of MHC class I (HLA-A, B, C; n = 4), CD112 (n = 4), and CD155 (n = 3) expression was assessed by flow cytometry (paired t test). Evaluation of NK ligand expression on TOV21G and OVCAR4 cells after dl922-947 infection (MOI 10, 48 h) using recombinant human Fc chimera proteins DNAM-1, NKG2D, NKp30, NKp44, and NKp46. (B) A schematic representation of the antigen-antibody complex. The recombinant human Fc chimera protein can bind to multiple ligands of the corresponding NK receptor. Summary data of independent experiments (n = 5 for each line) of (C) NKG2D, NKp30, NKp44, and NKp46 ligand expression, and (D) DNAM-1 ligand expression (paired t test).