Table 1.
Clinical characteristics of the patients
| Index | Control N = 50 | Mild HAPH N = 40 | Moderate HAPH N = 40 | Severe HAPH N = 40 | Total N = 170 |
|---|---|---|---|---|---|
| Male:female | 21:28 | 23:17 | 19:21 | 22:18 | 86:84 |
| Age (years) | 59.44 ± 0.73 | 59.95 ± 2. 10 | 61.05 ± 1.44 | 62.73 ± 1.56 | 62.36 ± 10.08 |
| Current residence | |||||
| 4500 (Ngari) | 10 | 2 | 7 | 1 | 20 |
| 3500 (Changdu) | 5 | 2 | 6 | 6 | 21 |
| 3658 (Lhasa) | 11 | 12 | 10 | 6 | 39 |
| 3000 (Lin Zhi) | 4 | 5 | 6 | 5 | 20 |
| 4507 (Nagqu) | 8 | 1 | 4 | 14 | 27 |
| 3836 (Shigatse) | 5 | 10 | 2 | 5 | 22 |
| 3700 (Shannan) | 7 | 6 | 5 | 3 | 21 |
| Living altitude (meters) | 3917.48 ± 68.56 | 3674.08 ± 55.01 | 3782.00 ± 80.27 | 3895.65 ± 84.05 | 3823.19 ± 36.81 |
| Education | |||||
| Primary | 1 | 9 | 7 | 3 | 20 |
| Junior High | 37 | 25 | 18 | 25 | 105 |
| Senior High | 11 | 5 | 14 | 9 | 39 |
| University | 1 | 2 | 1 | 3 | 6 |
| Smoking status | |||||
| Nonsmoker | 16 | 8 | 8 | 9 | 41 |
| Current smoker | 31 | 30 | 28 | 29 | 118 |
| Former smoker | 3 | 2 | 4 | 2 | 11 |
| Duration of diagnosis (years) | non | 4.30 ± 0.63 | 3.65 ± 1.78 | 8.78 ± 2.61** | 5.00 ± 0.65 |
| Average heart rate (prm) | 67.70 ± 8.13 | 65.4 ± 8.17* | 61.33 ± 4.49* | 60.05 ± 5.92* | 63.86 ± 7.86 |
| PAP， mm Hg | 24.96 ± 0.28 | 43.05 ± 0.77** | 59.10 ± 0.74** | 78.1 ± 0.98** | 49.76 ± 1.58 |
| SaO2 (%) | 93.94 ± 0.17 | 86.95 ± 0.26** | 81.15 ± 0.26** | 71.75 ± 0.51** | 84.06 ± 0.65** |
|
Hemoglobin (g/dL) |
179.20 ± 1.93 | 186.58 ± 4.02** | 197.35 ± 2.47** | 200.40 ± 1.88** | 190.19 ± 1.47 |
| Ejection fraction (%) | 76.24 ± 1.06 | 56.03 ± 1.63* | 53.00 ± 1.68* | 47.67 ± 17.40* | 59.29 ± 16.30 |
| New York Heart Association Heart Function Rating | |||||
| I | 50 | 1 | 50 | ||
| II | 1 | 4 | 7 | 12 | |
| III | 18 | 31 | 28 | 78 | |
| IV | 20 | 5 | 5 | 30 |
*
P < .05
**
P < .01, compared between groups.