Table 2.

Associations of HRV indexes with high altitude pulmonary hypertension (HAPH)

Parameters	B	95%CI	P value
Heart rate variability indexes of time domain of Holter
PNN50
SaO2	0.569	(0.247, 0.892)	.001
HAPH
Severe	−28.863	(−36.233, −21.493)	<.001
Moderate	−21.584	(−26.074, −17.095)	<.001
Mild	−12.561	(−15.43, −9.691)	<.001
Control	ref
SDNN
SaO2	0.947	(0.539, 1.355)	<.001
HAPH
Severe	−38.214	(−47.546, −28.882)	<.001
Moderate	−28.080	(−33.765, −22.396)	<.001
Mild	−13.884	(−17.517, −10.25)	<.001
Control	ref
SDANN
SaO2	0.882	(0.509, 1.254)	<.001
HAPH
Severe	−28.496	(−37.007, −19.986)	<.001
Moderate	−18.536	(−23.72, −13.352)	<.001
Mild	−11.547	(−14.861, −8.234)	<.001
Control	ref
RMSSD
SaO2	0.884	(0.477, 1.291)	<.001
HAPH
Severe	−23.976	(−33.278, −14.673)	<.001
Moderate	−20.709	(−26.375, −15.043)	<.001
Mild	−12.606	(−16.227, −8.984)	<.001
Control	ref
HRVTI
SaO2	0.902	(0.387, 1.417)	.001
HAPH
Severe	−40.649	(−52.414, −28.883)	<.001
Moderate	−31.003	(−38.169, −23.836)	<.001
Mild	−18.335	(−22.915, −13.754)	<.001
Control	ref
Heart rate variability indexes of frequency domain of Holter
TP
SaO2	10.991	(5.587, 16.395)	<.001
HAPH
Severe	−514.518	(−638.074, −390.962)	<.001
Moderate	−352.784	(−428.046, −277.523)	<.001
Mild	−194.383	(−242.489, −146.276)	<.001
Control	ref
VLF
SaO2	0.697	(0.28, 1.114)	.001
HAPH
Severe	−40.479	(−50.013, −30.945)	<.001
Moderate	−30.693	(−36.5, −24.885)	<.001
Mild	−15.864	(−19.576, −12.152)	<.001
Control	ref
LF
SaO2	0.811	(0.414, 1.208)	<.001
HAPH
Severe	−36.343	(−45.422, −27.265)	<.001
Moderate	−26.074	(−31.604, −20.544)	<.001
Mild	−13.047	(−16.582, −9.513)	<.001
Control	ref
HF
SaO2	0.593	(0.308, 0.878)	<.001
HAPH
Severe	−24.859	(−31.374, −18.345)	<.001
Moderate	−17.098	(−21.066, −13.129)	<.001
Mild	−9.935	(−12.472, −7.398)	<.001
Control	ref
LF/HF ratio
SaO2	<0.001	(0, 0)	.955
HAPH
Severe	−0.009	(−0.013, −0.005)	<.001
Moderate	−0.010	(−0.012, −0.007)	<.001
Mild	0.002	(0.001, 0.004)	.003
Control	ref