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. 2015 Jun 23;2015(6):CD001730. doi: 10.1002/14651858.CD001730.pub3

Burch 1999.

Methods Randomised controlled trial
Method of randomisation: computer generated
Concealment of allocation: sealed envelopes
Outcome assessor blinding: blinded research sociologist
Participants Country: UK
Patients referred to day hospital
 Exclusion criteria: dysphasic, required nursing or occupational therapy > twice per week
163 patients eligible (28 needed day hospital treatment, 21 refused consent, 9 operational problems at day centre)
 Participants randomised = 105
 Baseline function: Median (IQR) Barthel Index 15 (12‐17) and 15 (11‐17)
 Male: 36%
Age: mean (SD) 80.4 (7.6) years
Interventions Day hospital: care by multidisciplinary rehabilitation team, principally nursing assessment, occupational therapy and physiotherapy. Median number of treatments (interquartile range) 11.5 (5–20.5).
Day centre: rehabilitation provided by a physiotherapist and two support workers. Median number of treatments (interquartile range) 10 (5–14).
Outcomes 12 month follow up
 Death
 Institutional care
 Barthel Index
 Caregiver Strain Index
 Philadelphia Geriatric Morale scale
 Costs
Notes Total of 105 patients of whom 23 had a stroke diagnosis, 14 osteoarthritis, 13 fracture, 9 Parkinsonism
 Of the 55 patients randomised to day centre attendance, 10 transferred to day hospital
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Computer generated
Allocation concealment (selection bias) Low risk Quote: "Immediately after consent, subjects were randomly allocated to day hospital or day centre by a sequence of labelled tickets in sealed, opaque envelopes securely kept and opened by a senior ward clerk unattached to the trial team....computer generated blocks of 20."
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Reported as single blind which appears to have been the assessor, not participants or personnel
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Outcome assessments were undertaken by a blinded research sociologist
Quote: "The interviewer correctly identified 38/55 as day hospital and 20/38 as day centre, yielding kappa = 0.22 indicating poor agreement/successful blinding."
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Similar losses per group (˜30%), moderately high but similar reasons reported for both groups
Selective reporting (reporting bias) Unclear risk We were unable to obtain the pre‐study protocol so cannot determine risk of reporting bias
Other bias High risk 18% of participants randomised to day centre attendance transferred to the day hospital leading to possibility of contamination (the experiment and control groups becoming mixed)