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. 2014 Dec 13;2014(12):CD001941. doi: 10.1002/14651858.CD001941.pub3

Laserna 2003.

Methods Single‐centre, open, cross‐over study
Participants 10 participants with kyphoscoliosis and chronic hypercapnic respiratory failure
Interventions Control: spontaneous ventilation
 Experimental 1: nocturnal ventilation with bilevel airway pressure
 Experimental 2: nocturnal volume‐cycle ventilation
Outcomes 1‐month improvement in sleep parameters, clinical symptoms and arterial blood gas
Notes
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Information was not provided
Allocation concealment (selection bias) Unclear risk Information was not provided
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No party was blinded to the intervention
Blinding of outcome assessment (detection bias) 
 All outcomes High risk The outcome assessor was not blinded to the intervention
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No loss to follow‐up
Selective reporting (reporting bias) Low risk Outcomes presented in the results section matched those reported in the methods