Methods |
Single‐centre, open, cross‐over study |
Participants |
10 participants with kyphoscoliosis and chronic hypercapnic respiratory failure |
Interventions |
Control: spontaneous ventilation
Experimental 1: nocturnal ventilation with bilevel airway pressure
Experimental 2: nocturnal volume‐cycle ventilation |
Outcomes |
1‐month improvement in sleep parameters, clinical symptoms and arterial blood gas |
Notes |
— |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Random sequence generation (selection bias) |
Unclear risk |
Information was not provided |
Allocation concealment (selection bias) |
Unclear risk |
Information was not provided |
Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
No party was blinded to the intervention |
Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
The outcome assessor was not blinded to the intervention |
Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No loss to follow‐up |
Selective reporting (reporting bias) |
Low risk |
Outcomes presented in the results section matched those reported in the methods |