Total costs
Study	Study design	Outcomes	Results
Corney 2003	Randomized controlled trial	Primary care total costs	Primary care costs 6 months Pre treatment Int 101 (87) (n=90) Con 113 (104) (n=89) Post treatment Int 321 (191) (n=82) Con 149 (194) (n=79) Absolute change Post treatment 172 Relative % change 115.4 Absolute change from baseline Int 220, Con 36 Difference in absolute change from baseline 184 Primary care costs 12 months Pre treatment Int 101 (87) (n=90) Con 113 (104) (n=89) Post treatment Int 157 (186) (n=75) Con 174 (215) (n=68) Absolute change Post treatment ‐17 Relative % change ‐9.8 Absolute change from baseline Int 56, Con 61 Difference in absolute change from baseline ‐5
King 2000a	Randomized controlled trial	Primary care total costs	Primary care costs 12 months Post treatment Int 86.6 (59.7) (n=63) Con 118.5 (93.7) (n=67) Absolute change post ‐31.9 Relative % change ‐26.9
King 2000b	Randomized controlled trial	Primary care total costs	Primary care costs 12 months Post treatment Int 98.4 (84.5) (n=67) Con 118.5 (93.7) (n=67) Absolute change post ‐20.1 Relative % change ‐17.0