Figure 3.

Results of taurine supplementation therapy for 24-months. (A) Taurine levels in the blood of both affected individuals (IV:1 and IV:3) before and after 6-months, 1-year and 2-years of taurine supplementation. (B) Results of the echocardiography show that the cardiomyopathy of both affected individuals (IV:1 and IV:3) has been corrected after 2-years of taurine supplementation. LVESD: left ventricular end-systolic diameter, LVEDD: left ventricular end diastolic diameter, EF: ejection fraction, FS: fractional shortening. Green and red numbers represent normal and abnormal values respectively. (C, D) Fundus photographs and macular OCT of the right eye (C) and left eye (D) of the patient IV:3 at baseline and after 24 months of taurine supplementation; anatomical stability with preservation of foveal photoreceptors can be noted.