Table 1.
The findings and results of the studies that entered the study
| Result of study | Apparent survival benefit | Irrespective of the adjuvant treatment | Complication risks after immediate BR | Mastectomy and BR for cancer | Implant-based reconstruction compared to mastectomy | |
|---|---|---|---|---|---|---|
| Outcomes | Overall survival | Overall survival | Overall survival | Overall survival | Disease-free survival, overall survival | |
| Follow up median | Mastectomy alone | 23.4 | 8.6 | Not available | Not available | Not available |
| IBR | 23.4 | 8.6 | Not available | Not available | Not available | |
| Lymph-node | Mastectomy alone | 324/267/167 | 41/16/48 | Not available | Not available | 11, 5, 27 |
| IBR | 384/236/138 | 137/102/100 | Not available | 21/37/22 | 5, 10,4 | |
| stage (I/II/III/I V) | Mastectomy alone | Not available | Not available | Not available | Not available | 38, 19,28 |
| IBR | Not available | Not available | Not available | Not available | 41,31,15 | |
| Age median | Mastectomy alone | 45 | Not available | Not available | Not available | 58 |
| IBR | 45 | Not available | Not available | 46 | 48 | |
| Patients (n) | Mastectomy alone | 758 | 105 | 9250 | 210 | |
| IBR | 758 | 339 | 5644 | 400 | 681 | |
| Study design | RCS | CC | RCS | CC | PCR | |
| Author | Platt et al., 2015 | Aurilio et al., 2015 | Jagsi et al., 2016 | Howes et al., 2019 | Miller et al., 2016 | |