Table 1. Clinical Information on All Patients and Subgroups.
| Characteristic | Reperfusion statusa | ||||
|---|---|---|---|---|---|
| All (N = 182) | Minimal (n = 32) | Major (n = 67) | Partial (n = 41) | Unknown (n = 42) | |
| Male | 85 (46.7) | 19 (59.4) | 34 (50.7) | 17 (41.5) | 15 (35.7) |
| Age, mean (SD), y | 65 (15) | 62 (15) | 64 (16) | 67 (14) | 64 (17) |
| Hypertension | 126 (69.2) | 26 (81) | 41 (61.2) | 31 (75.6) | 28 (66.7) |
| Diabetes | 44 (24.2) | 8 (25.0) | 13 (19.4) | 12 (29.3) | 11 (26.2) |
| Dyslipidemia | 83 (45.6) | 18 (56.3) | 28 (41.8) | 25 (61.0) | 12 (28.6) |
| Atrial fibrillation | 58 (31.9) | 8 (25.0) | 23 (34.3) | 16 (39.0) | 11 (26.2) |
| Site of occlusionb | |||||
| MCA M1 | 86 (59.3) | 10 (43.5) | 38 (62.3) | 21 (60.0) | 17 (63.0) |
| MCA M2 | 21 (14.5) | 8 (34.8) | 4 (6.6) | 4 (11.4) | 5 (18.5) |
| MCA M3 | 4 (2.8) | 0 | 2 (3.3) | 2 (5.7) | 1 (3.7) |
| ICA | 34 (23.4) | 5 (21.7) | 17 (27.9) | 8 (22.9) | 4 (14.8) |
| Treatment methods | |||||
| IV tPA | 101 (55.5) | 17 (53.1) | 36 (53.7) | 22 (53.7) | 26 (61.9) |
| Thrombectomy | 139 (76.4) | 22 (68.8) | 60 (89.6) | 31 (75.6) | 26 (61.9) |
| No treatment | 19 (10.4) | 6 (18.8) | 2 (3.0) | 4 (9.8) | 7 (16.7) |
| Onset to treatment time, median (IQR), h | 6.0 (4.6-8.3) | 7.1 (4.7-8.4) | 6.0 (4.6-9.2) | 5.6 (3.8-7.1) | 6.6 (4.9-8.8) |
| Baseline DWI lesion volume, median (IQR), mL | 28 (11-60) | 42 (16-131) | 19 (9-47) | 37 (16-83) | 30 (14-61) |
| Baseline Tmax lesion volume, median (IQR), mL | 116 (67-168) | 105 (56-153) | 111 (69-153) | 156 (80-210) | 123 (82-171) |
| PWI:DWI mismatch ratio, median (IQR)c | 3.9 (2.2-9.7) | 2.6 (1.4-4.8) | 5.2 (2.7-12.6) | 3.8 (2.5-7.0) | 3.6 (2.1-8.9) |
| Baseline NIHSS score, median (IQR)d | 15.0 (10.0-19.0) | 13.0 (8.5-21.0) | 15.0 (10.0-19.0) | 17.0 (12.0-20.0) | 14.0 (11.0-19.0) |
| Symptomatic hemorrhage | 13 (7.1) | 4 (12.5) | 4 (6.0) | 2 (4.9) | 3 (7.1) |
| Reperfusion rate, median (IQR), % | 74 (29-100) | 0 (0-11) | 100 (96-100) | 56 (43-68) | NA |
| Final infarct volume, median (IQR), mL | 54 (16-117) | 86 (35-257) | 23 (9-64) | 82 (27-163) | 52 (21-109) |
| mRS score at 90 d, median (IQR)e | 3 (1-4) | 3 (1-4) | 2 (1-3) | 4 (3-5) | 3 (1-4) |
Abbreviations: DWI, diffusion-weighted imaging; ICA, internal carotid artery; IQR, interquartile range; IV tPA, intravenous tissue plasminogen activator; MCA, middle cerebral artery; mRS, modified Rankin scale; NA, not applicable; NIHSS, National Institutes of Health Stroke Scale; PWI, perfusion-weighted imaging; Tmax, time to maximum of the residue function.
Unless otherwise indicated, data are expressed as number (percentage) of patients.
Identified on initial digital subtraction angiography. Only 80% of patients received initial digital subtraction angiography.
The upper limit of mismatch ratio was set to 20 if a small or no ischemic core lesion presented on baseline.
Scores range from 0 to 42, with higher scores indicating more severe stroke symptoms.
Scores range from 0 to 6, with higher scores indicating worse functional outcome.