Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 5;19(4):2832–2838. doi: 10.3892/ol.2020.11367

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Kong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 5. — LINK-A lncRNA knockdown mediates the inhibition of migration, invasion and stemness of MG-63 and U2OS osteosarcoma cell lines through TGF-β1. (A-C) LINK-A lncRNA knockdown significantly inhibited, whereas treatment with TGF-β1 (10 ng/ml) significantly promoted the (A) migration, (B) invasion and (C) stemness of cells of MG-63 and U2OS osteosarcoma cell lines. In addition, exogenous TGF-β1 co-treatment significantly attenuated these effects of LINK-A lncRNA knockdown. For invasion and migration data, C group was set to ‘100’ and all other groups were normalized to C. *P<0.05. C, control; LINK-A, long intergenic non-coding RNA for kinase activation; lncRNA, long non-coding RNA; NC, negative control; TGF-β1, transforming growth factor β1.