Table I.
Locus specific probes used for FISH.
| Probe | Cytoband | Position [NCBI36/hg18] | Genes/locus | Result (signals on…) |
|---|---|---|---|---|
| RP11-434D11 | 5q23.2 | chr5:126,045,879-126,232,850 | n.d. | der(5) |
| RP11-114H7 | 5q23.3 | chr5:130,306,745-130,460,728 | n.d. | der(5) |
| LSI EGR1/D5S721, D5S23 (Vysis) | 5q31.2 | chr5:137,829,080-137,832,903 | EGR1 | der(5) |
| LSI PDGFRB DCBAP (Vysis) | 5q33.1 | chr5:149,473,595-149,515,615 | PDGFRB | der(9) |
| 5qTEL (Vysis) | 5q35.3 | chr5:180,510,748-180,711,420 | D5S2907 | der(9) |
| 9pTEL (Vysis) | 9p24.3 | chr9:131,486-331,767 | 305J7-T7 | der(5) |
| POSEIDON™ MLL/MLLT3 DCDFP (Kreatech) | 9p21.3 | chr9:20,331,667-20,612,514 | MLLT3 | der(5) |
| SPEC CDKN2A/CEN9 DCP (Zytovision) | 9p21.3 | chr9:21,957,751-21,965,038 | CDKN2A/B | biallelic deletion (9)(p21.3p21.3) |
| LSI BCR/ABL1 DCDFP (Vysis) | 9q34.12 | chr9:132,579,089-132,752,883 | ABL1 | der(9) |
| 9qTEL (Vysis) | 9q34.3 | chr9:140,000,171-140,200,260 | D9S325 | der(9) |
| SPEC BIRC3/MALT1 DCDFP (Zytovision) | 11q22.3 | chr11:101,693,404-101,713,675 | BIRC3 | #11 |
| RP11-142A12 | 16p12.1 | chr16:26,595,070-26,757,869 | n.d | der(16) |
| RP11-147I4 | 16p12.1 | chr16:27,071,343-27,211,332 | KDM8, NSMCE1 | der(16) |
| RP11-159J3 | 16p11.2 | chr16:28,012,684-28,171,002 | XPO6 | der(16) |
| SPEC FUS DCBAP (Zytovision) | 16p11.2 | chr16:31,098,954-31,110,600 | FUS | signal split on der(16) and der(19) |
| SPEC TP53/ATM DCP (Zytovision) | 17p13.1 | chr17:7,512,445-7,531,588 | TP53 | #17 |
| RP11-21J15 | 19q13.31 | chr19:49,726,602-49,900,222 | CEACAM22P, IGSF23, PVR, CEACAM19 | der(19) |
| RP11-84C16 | 19q13.31 | chr19:49,089,546-50,686,777 | BCL3 | der(19) |
| RP11-492P7 | 19q13.32 | chr19:51,987,986-52,169,539 | AP2S, ARHGAP35 | der(19) |
| SPEC 19q13/19p13 DCP (Zytovision) | 19q13.32 | chr19:52,477,388-53,038,398 | GLTSCR1, GLTSCR2, CRX | der(19) |
| RP11-3N16 | 19q13.32 | chr19:53,269,619-53,431,708 | PLA2G4C, LIG1, CARD8 | der(19) |
| RP11-264M8 | 19q13.33 | chr19:54,767,615-54,925,355 | PRRG2, PRRG2, IRF3, BCL2L12, PRMT1, CPTC1 | der(16) |
Locus specific probes used for FISH together with their location according to genome browser version NCBI36/hg18. This version was used as some applied FISH-probes are no longer available in newer genome browser versions. Results obtained are presented using standard gene abbreviations and such used according to the international system of cytogenomic nomenclature. der, derivative; FISH, fluorescence in situ hybridization.