Table II.

Gene mutation rates in a total of 81 patients with hepatocellular carcinoma, including 26 samples with tTMB-H and 55 samples with tTMB-L.

Gene	tTMB-H, %	tTMB-L, %	P-value
TP53	65.38	50.91	0.2419
TERT	42.31	29.09	0.3135
ARID1A	34.62	5.45	0.0013b
CTNNB1	34.62	10.91	0.0152a
AXIN1	11.54	12.73	1
MLL2	11.54	9.09	0.7071
LRP1B	11.54	7.27	0.6749
RB1	7.69	10.91	1
ARID2	15.38	5.45	0.2031
APC	11.54	5.45	0.3798
MLL	15.38	3.64	0.0803
ATRX	7.69	5.45	0.6539
PTEN	7.69	5.45	0.6539
PBRM1	11.54	3.64	0.3211
KRAS	3.85	7.27	1
ATM	3.85	7.27	1
NCOR1	15.38	1.82	0.0347a

^aP<0.05

^bP<0.01. tTMB-L, low tumor tissue mutation burden; tTMB-H, high tumor tissue mutation burden.