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. 2020 Feb 17;19(4):2861–2869. doi: 10.3892/ol.2020.11404

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Copyright: © Ling et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — HBx induces the expression of pro-inflammatory cytokines IL-6, IL-1β and IL-18. (A) HBx promoted a significant increase in IL-6 levels in the sera of mice (n=10). ***P<0.001 vs. Control and Mock. (B) HBx increased the levels of IL-1β in the sera of mice. n=10. ***P<0.001 vs. Control and Mock. (C) HBx increased IL-18 levels in the sera of mice. n=10. ***P<0.001 vs. Control and Mock. Control, blank control group treated with plasmid solvent; Mock, null plasmid control group; HBx, experimental group; IL, interleukin.