Figure 5.
Muscle Patterning Defects in Tbx5lx/lx;Osr2Cre Mutants Are Detected at E12.0
Dorsal view of control (A, C, E, G, and I) and mutant (B, D, F, H, and J) forelimbs at E10.5 (A and B), E11.5 (C–F), E12.0 (G and H), and E12.5 (I and J). Muscle cells are detected by in situ hybridization against Pax3 (A and B), MyoD (C and D), or Myogenin (E, F, G, H, I, and J). Arrowheads and asterisks point to clustering defects in the mutant forelimbs (J) compared to the controls (I).