Downregulation of TMOD1 enhances cell motility. The stably transfected CaSki cells were seeded in 6-well plates and scratched the next day. (A) The images were captured at 0 and 24 h, respectively, and (B) the corresponding quantitative results are demonstrated. The data are presented as the mean ± standard deviation (n=3). Scale bar, 150 µm. **P<0.001 vs. control shRNA group; #P<0.01 vs. TMOD1 shRNA-1 group. Scale bar, 100 µm. TMOD1, tropomodulin-1; Con, control; sh, short hairpin.