. 2020 Feb 13;142(10):4648–4662. doi: 10.1021/jacs.9b11351

Table 1. Kinetic Parameters for Covalent Inhibition of AnAbfA and AkAbfB by α-l-Arabinofuranosidase Compounds 1, 2, 3, and 6^a.

compd	K_I (μM)	k_inact (min^–1)	k_inact/K_I (s^–1 M^–1)
AnAbfA (GH51)
1	nd	nd	<0.1
2	140 ± 20	0.33 ± 0.02	39
3	210 ± 30	0.09 ± 0.01	7.1
6	nd	nd	160 ± 20
AkAbfB (GH54)
1	nd	nd	<0.1
2	320 ± 50	0.54 ± 0.07	28
3	320 ± 40	0.12 ± 0.01	6.2
6	nd	nd	240 ± 30

For reactions with compound 6, it was not possible to obtain distinct k_inact and K_I parameters; only the combined k_inact/K_I parameter determined from the slope of the k_app vs [I] curve is shown for these cases. nd: not determined.

Table 1. Kinetic Parameters for Covalent Inhibition of AnAbfA and AkAbfB by α-l-Arabinofuranosidase Compounds 1, 2, 3, and 6a.

Table 1. Kinetic Parameters for Covalent Inhibition of AnAbfA and AkAbfB by α-l-Arabinofuranosidase Compounds 1, 2, 3, and 6^a.