Figure 8.

CNT-GelMA guiding maturation of cardiac tissues through mechanotransduction signaling. (A) Heat map comparing a panel of transcripts linked to cytoplasmic structure, Rho family, mechanotransduction, and growth across cardiac tissues cultured for 3 and 5 days on CNT- and rGO-GelMA (N =3). (B) Results of qRT-PCR to measure the expression of genes employed in (A) for cardiac tissues matured for 5 days on CNT-GelMA compared to in vivo cardiac tissues (N = 3).(C) Summary of the effects of multimodal cues on cardiomyocyte maturation and functionality (*P < 0.05, **P < 0.005, ***P < 0.005). Error bars represent standard deviation.