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Effect of 8-OH-DPAT on precontracted tissue with 100 µM ACh after a 10-min (black column) incubation period (white column = at baseline). a FA group. b HDMA group. c O3 group. d HDMA+O3 group. * Tension is significantly lower than control. Values are means ±SE, n = 6 (p = 0.05).