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Relationship between macrophage polarity and tumor cell proliferation. Tissue microarrays (TMAs) were immunostained with antibodies for Ki67, CD163, and CD68 followed by automated quantification of the stained cells in stromal (A), parenchymal (B), and luminal (C) areas. The gray triangles above the figures indicate results of tests for trend across ordered categories; only stromal macrophages are related to tumor cell proliferation.
