Table 1.
Prevalence of Pathogenic Organisms in the Lower Airways of Preschool Children with Cystic Fibrosis in Irish Cystic Fibrosis Centers, 2010–2018
| 2010–2012 (n = 87) | 2013–2015 (n = 149) | 2016–2018 (n = 99) | 2012–2018 (n = 285) | Breuer et al. (1) 2012–2018 (n = 866) | P Value | |
|---|---|---|---|---|---|---|
| P. aeruginosa | 3 (3.4) | 8 (5.4) | 1 (1) | 10 (3.5) | 51 (5.9) | 0.11 |
| P. aeruginosa PCR | 4/65 (6.2) | 16/101 (15.8) | 2/80 (2.5) | 19 (8.9) | NA | NA |
| S. aureus | 14 (16.1) | 35 (23.5) | 24 (24.2) | 66 (23.2) | 78 (9.1) | <0.001 |
| H. influenzae | 30 (34.5) | 40 (26.8) | 25 (25.3) | 74 (26) | 72 (8.3) | <0.001 |
| Aspergillus sp. | 5 (5.7) | 4 (2.7) | 4 (4) | 9 (3.2) | 97 (11.2) | <0.001 |
Definition of abbreviations: H. influenzae = Haemophilus influenzae; NA = not available; P. aeruginosa = Pseudomonas aeruginosa; S. aureus = Staphylococcus aureus.
Comparison is made with data from Breuer and colleagues (1). Data are shown as n (%).