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. 2020 Mar 12;21:11. doi: 10.1186/s12865-020-0339-3

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© The Author(s). 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Correlation between Inflammatory biomarkers and symptom severity in male and female athletes following a sport-related concussion. Eotaxin, interferon (IFN)-γ, interleukin (IL)-8, interferon gamma-induced protein (IP)-10, monocyte chemoattractant protein (MCP)-1, − 4, macrophage inflammatory protein (MIP)-1β, Myeloperoxidase (MPO), thymus and activation-regulated chemokine (TARC), and tumor necrosis factor (TNF)-α. Plots show the contributions of biomarkers measured in the subacute period following injury towards symptom severity in male (n = 20) and female (n = 20) athletes. Bars represent variable loadings and the standard error derived from bootstrapped resampling (5000 iterations, male = red, female = green). Significance is displayed at p < 0.05 *, p < 0.01** and p < 0.001***