ACR50 (Analysis 1): Odds Ratios, Risk Ratios and Risk Difference for all treatment comparisons ‐ random‐effects model
Treatment	Reference	OR (95% CrI)	RR (95% CrI)	RD % (95% Crl)
PL + MTX/MTX	PL	3.66 (1.69,6.81)	3.15 (1.62,5.14)	0.13 (0.04,0.24)
DMARD/DMARD + PL		0.98 (0.37,2.38)	0.98 (0.38,2.20)	0.00 (‐0.04,0.07)
MTX + DMARD		5.57 (2.31,13.66)	4.36 (2.11,8.02)	0.20 (0.07,0.39)
SD ETN SC		6.94 (3.38,13.10)	5.09 (2.90,7.94)	0.25 (0.13,0.38)
SD ADA SC		3.69 (2.13,6.72)	3.16 (1.98,5.13)	0.13 (0.07,0.23)
SD TOFA PO		6.44 (3.31,13.07)	4.82 (2.87,7.77)	0.23 (0.12,0.39)
SD GOLI SC		8.10 (3.04,22.03)	5.65 (2.70,10.08)	0.28 (0.11,0.52)
SD GOLI IV		6.49 (2.15,18.77)	4.85 (2.00,9.34)	0.23 (0.06,0.48)
SD TOCI IV		5.43 (2.12,13.52)	4.26 (1.97,8.06)	0.20 (0.06,0.39)
SD RITUX IV		2.52 (0.29,13.36)	2.30 (0.30,7.87)	0.08 (‐0.04,0.39)
SD ABA SC		9.95 (2.69,46.12)	6.40 (2.43,13.14)	0.33 (0.09,0.68)
SD CERTO SC		9.56 (3.04,34.80)	6.26 (2.70,11.93)	0.32 (0.10,0.63)
SD ETN SC + MTX		14.81 (6.84,31.08)	8.01 (4.78,12.05)	0.43 (0.26,0.59)
SD INF IV + MTX		11.26 (4.80,24.64)	6.94 (3.82,10.64)	0.36 (0.19,0.54)
SD ABA IV + MTX		14.62 (6.12,33.05)	7.97 (4.48,12.16)	0.43 (0.23,0.61)
SD ADA SC + MTX		23.24 (9.03,57.59)	9.75 (5.74,14.38)	0.54 (0.32,0.72)
SD CERTO SC + MTX/CERTO+ MTX		21.19 (8.18,46.26)	9.46 (5.51,13.45)	0.52 (0.30,0.69)
SD RITUX IV + MTX		9.14 (3.91,21.04)	6.08 (3.26,9.92)	0.31 (0.14,0.51)
SD TOFA PO + MTX		23.26 (9.75,57.30)	9.82 (6.11,14.14)	0.54 (0.34,0.72)
SD GOLI SC + MTX		23.12 (8.75,58.38)	9.79 (5.68,14.19)	0.54 (0.32,0.72)
SD ABA SC + MTX		18.02 (6.44,49.02)	8.78 (4.70,13.72)	0.48 (0.25,0.68)
SD GOLI IV + MTX		8.64 (3.20,22.14)	5.88 (2.79,10.06)	0.30 (0.12,0.52)
SD ANA SC + MTX		10.68 (3.49,30.43)	6.67 (3.01,11.55)	0.35 (0.13,0.59)
SD TOCI IV + MTX		7.50 (2.32,22.43)	5.36 (2.13,10.30)	0.27 (0.08,0.52)
SD CERTO SC + DMARD		5.17 (1.87,14.27)	4.12 (1.77,8.03)	0.19 (0.05,0.41)
SD ADA SC + DMARD		3.09 (0.76,11.16)	2.74 (0.78,6.94)	0.11 (‐0.01,0.35)
SD ETN SC + DMARD		12.68 (4.15,38.46)	7.36 (3.45,12.62)	0.39 (0.16,0.65)
SD TOCI SC + DMARD		4.91 (1.24,18.43)	3.95 (1.22,9.00)	0.18 (0.01,0.48)
LD ADA SC		3.33 (1.59,7.53)	2.92 (1.53,5.52)	0.12 (0.03,0.26)
LD ETN SC		3.51 (1.56,7.76)	3.04 (1.50,5.60)	0.12 (0.03,0.27)
LD GOLI IV		3.85 (1.15,12.60)	3.27 (1.14,7.53)	0.14 (0.01,0.38)
LD TOCI IV		0.65 (0.11,2.67)	0.67 (0.12,2.43)	‐0.02 (‐0.06,0.08)
LD ADA SC + MTX		16.49 (6.28,46.62)	8.42 (4.58,13.41)	0.46 (0.24,0.68)
LD RITUX IV + MTX		8.07 (3.19,18.75)	5.62 (2.79,9.50)	0.28 (0.12,0.48)
LD ADA IV + MTX		14.69 (2.25,82.04)	7.93 (2.08,15.00)	0.43 (0.07,0.78)
LD ABA IV + MTX		7.85 (2.93,21.08)	5.52 (2.62,9.82)	0.28 (0.10,0.50)
LD ANA SC + MTX		7.33 (1.54,32.97)	5.26 (1.49,11.70)	0.26 (0.03,0.61)
LD CERTO SC + MTX		14.70 (4.41,47.72)	7.99 (3.58,13.38)	0.43 (0.17,0.69)
LD ETN SC + MTX		12.99 (4.49,37.72)	7.49 (3.65,12.44)	0.40 (0.18,0.64)
LD GOLI IV + MTX		7.58 (2.45,24.09)	5.38 (2.22,10.42)	0.27 (0.08,0.54)
LD TOCI IV + MTX		6.08 (1.95,18.19)	4.64 (1.83,9.22)	0.22 (0.05,0.46)
LD TOFA PO + MTX		12.84 (2.98,48.04)	7.40 (2.66,13.00)	0.39 (0.11,0.70)
HD TOCI IV		9.85 (4.54,19.49)	6.40 (3.64,9.73)	0.33 (0.18,0.48)
HD TOFA PO		10.26 (5.02,20.82)	6.53 (3.97,9.90)	0.34 (0.19,0.50)
HD ADA SC		4.69 (2.28,10.74)	3.82 (2.09,7.00)	0.17 (0.07,0.34)
HD ETN SC		7.12 (2.81,17.55)	5.19 (data points,9.25)	0.25 (0.10,0.47)
HD GOLI SC		9.57 (3.90,21.77)	6.26 (3.25,10.12)	0.32 (0.15,0.52)
HD ABA SC		14.48 (3.81,62.31)	7.86 (3.20,14.09)	0.42 (0.14,0.74)
HD INF IV + MTX		18.36 (7.49,43.86)	8.92 (5.14,13.22)	0.48 (0.28,0.67)
HD TOCI IV + MTX		17.54 (7.25,37.88)	8.70 (5.10,12.70)	0.47 (0.27,0.64)
HD TOFA PO + MTX		18.47 (7.83,45.79)	8.90 (5.26,13.32)	0.49 (0.29,0.68)
HD GOLI SC + MTX		17.77 (6.82,47.15)	8.77 (4.86,13.44)	0.48 (0.26,0.68)
HD CERTO SC + MTX		24.79 (10.00,59.86)	10.08 (6.17,14.60)	0.56 (0.35,0.73)
HD ADA SC + MTX		20.68 (6.34,70.20)	9.33 (4.67,14.68)	0.51 (0.24,0.75)
HD TOCI IV + DMARD		3.61 (1.09,11.27)	3.11 (1.08,7.06)	0.13 (0.01,0.35)
SD ANA SC + SD ETN SC + MTX		9.29 (2.84,33.61)	6.10 (2.51,11.95)	0.32 (0.10,0.62)
SD ANA SC + LD ETN SC + MTX		14.26 (4.13,48.43)	7.82 (3.39,13.56)	0.42 (0.16,0.69)
DMARD/DMARD + PL	PL + MTX/MTX	0.27 (0.12,0.63)	0.31 (0.15,0.68)	‐0.13 (‐0.23,‐0.05)
MTX + DMARD		1.57 (0.88,2.82)	1.41 (0.90,2.15)	0.08 (‐0.02,0.21)
SD ETN SC		1.91 (1.28,2.89)	1.63 (1.19,2.29)	0.12 (0.04,0.20)
SD ADA SC		1.03 (0.50,2.31)	1.03 (0.58,2.00)	0.00 (‐0.11,0.13)
SD TOFA PO		1.80 (0.72,4.69)	1.56 (0.78,3.18)	0.11 (‐0.06,0.29)
SD GOLI SC		2.27 (0.89,6.00)	1.82 (0.91,3.47)	0.15 (‐0.02,0.37)
SD GOLI IV		1.81 (0.74,4.28)	1.57 (0.78,2.76)	0.10 (‐0.05,0.31)
SD TOCI IV		1.52 (0.69,3.30)	1.38 (0.74,2.45)	0.07 (‐0.06,0.23)
SD RITUX IV		0.71 (0.10,3.42)	0.75 (0.12,2.35)	‐0.05 (‐0.19,0.24)
SD ABA SC		2.80 (0.61,14.74)	2.05 (0.67,5.45)	0.20 (‐0.08,0.57)
SD CERTO SC		2.61 (0.70,13.42)	1.99 (0.75,5.34)	0.19 (‐0.06,0.53)
SD ETN SC + MTX		4.16 (2.76,6.35)	2.56 (1.93,3.64)	0.30 (0.19,0.40)
SD INF IV + MTX		3.11 (2.05,4.77)	2.19 (1.68,2.99)	0.23 (0.12,0.34)
SD ABA IV + MTX		4.07 (2.66,6.22)	2.53 (1.93,3.43)	0.29 (0.17,0.41)
SD ADA SC + MTX		6.35 (3.76,11.26)	3.10 (2.31,4.37)	0.40 (0.26,0.54)
SD CERTO SC + MTX/CERTO+ MTX		5.80 (3.65,9.41)	2.99 (2.25,4.21)	0.38 (0.24,0.50)
SD RITUX IV + MTX		2.54 (1.53,4.27)	1.95 (1.37,2.78)	0.18 (0.07,0.31)
SD TOFA PO + MTX		6.49 (3.80,11.61)	3.11 (2.28,4.56)	0.41 (0.26,0.54)
SD GOLI SC + MTX		6.39 (3.32,12.48)	3.10 (2.14,4.71)	0.40 (0.24,0.54)
SD ABA SC + MTX		5.06 (2.49,10.03)	2.81 (1.88,4.20)	0.35 (0.17,0.51)
SD GOLI IV + MTX		2.37 (1.22,4.82)	1.87 (1.16,2.88)	0.17 (0.03,0.34)
SD ANA SC + MTX		2.99 (1.27,6.77)	2.14 (1.21,3.49)	0.22 (0.04,0.42)
SD TOCI IV + MTX		2.10 (0.78,5.43)	1.74 (0.81,3.13)	0.14 (‐0.04,0.36)
SD CERTO SC + DMARD		1.45 (0.47,4.57)	1.34 (0.55,3.01)	0.06 (‐0.12,0.30)
SD ADA SC + DMARD		0.87 (0.26,3.00)	0.89 (0.30,2.27)	‐0.02 (‐0.16,0.21)
SD ETN SC + DMARD		3.56 (1.36,9.54)	2.37 (1.25,4.09)	0.26 (0.05,0.49)
SD TOCI SC + DMARD		1.37 (0.41,4.84)	1.28 (0.47,2.92)	0.05 (‐0.12,0.33)
LD ADA SC		0.95 (0.37,2.61)	0.96 (0.44,2.15)	‐0.01 (‐0.14,0.15)
LD ETN SC		0.98 (0.50,1.88)	0.98 (0.57,1.64)	0.00 (‐0.10,0.11)
LD GOLI IV		1.08 (0.37,2.92)	1.06 (0.43,2.13)	0.01 (‐0.12,0.21)
LD TOCI IV		0.18 (0.03,0.66)	0.22 (0.04,0.71)	‐0.14 (‐0.25,‐0.04)
LD ADA SC + MTX		4.55 (2.36,9.09)	2.67 (1.83,3.95)	0.32 (0.16,0.49)
LD RITUX IV + MTX		2.22 (1.29,3.78)	1.78 (1.22,2.57)	0.15 (0.04,0.29)
LD ADA IV + MTX		4.07 (0.70,20.43)	2.52 (0.75,4.91)	0.29 (‐0.05,0.63)
LD ABA IV + MTX		2.19 (1.15,4.20)	1.78 (1.11,2.65)	0.15 (0.02,0.31)
LD ANA SC + MTX		2.01 (0.54,8.21)	1.67 (0.59,3.74)	0.13 (‐0.07,0.46)
LD CERTO SC + MTX		4.12 (1.67,10.42)	2.54 (1.49,4.24)	0.30 (0.08,0.52)
LD ETN SC + MTX		3.66 (1.61,8.16)	2.40 (1.43,3.82)	0.27 (0.08,0.47)
LD GOLI IV + MTX		2.13 (0.83,5.69)	1.75 (0.85,3.06)	0.14 (‐0.03,0.38)
LD TOCI IV + MTX		1.71 (0.63,4.45)	1.50 (0.68,2.88)	0.09 (‐0.07,0.30)
LD TOFA PO + MTX		3.54 (1.05,10.97)	2.35 (1.05,4.11)	0.26 (0.01,0.53)
HD TOCI IV		2.69 (1.64,4.53)	2.02 (1.42,3.00)	0.19 (0.09,0.30)
HD TOFA PO		2.91 (1.13,6.96)	2.11 (1.09,3.99)	0.21 (0.02,0.39)
HD ADA SC		1.31 (0.53,3.66)	1.23 (0.61,2.74)	0.04 (‐0.10,0.23)
HD ETN SC		2.00 (0.98,4.13)	1.68 (0.98,2.69)	0.13 (0.00,0.30)
HD GOLI SC		2.66 (1.32,5.56)	2.01 (1.22,3.29)	0.19 (0.05,0.36)
HD ABA SC		3.98 (0.87,21.43)	2.48 (0.90,6.26)	0.29 (‐0.02,0.63)
HD INF IV + MTX		5.06 (2.95,8.88)	2.80 (2.04,4.07)	0.35 (0.20,0.48)
HD TOCI IV + MTX		4.85 (2.84,8.32)	2.77 (1.98,4.06)	0.34 (0.20,0.46)
HD TOFA PO + MTX		5.23 (2.96,9.43)	2.84 (2.08,4.16)	0.35 (0.20,0.50)
HD GOLI SC + MTX		4.96 (2.55,10.15)	2.78 (1.90,4.24)	0.34 (0.17,0.51)
HD CERTO SC + MTX		6.96 (4.03,12.34)	3.21 (2.38,4.77)	0.42 (0.28,0.55)
HD ADA SC + MTX		5.77 (2.26,15.13)	2.96 (1.80,4.72)	0.38 (0.15,0.58)
HD TOCI IV + DMARD		0.99 (0.37,2.99)	1.00 (0.43,2.21)	0.00 (‐0.13,0.21)
SD ANA SC + SD ETN SC + MTX		2.65 (0.91,7.95)	1.99 (0.92,3.62)	0.19 (‐0.01,0.45)
SD ANA SC + LD ETN SC + MTX		3.92 (1.35,11.55)	2.48 (1.27,4.39)	0.28 (0.05,0.53)
MTX + DMARD	DMARD/DMARD + PL	5.73 (2.15,15.44)	4.44 (1.92,10.18)	0.20 (0.08,0.38)
SD ETN SC		7.00 (3.18,16.12)	5.12 (2.54,10.99)	0.24 (0.15,0.37)
SD ADA SC		3.82 (1.49,10.43)	3.24 (1.41,8.32)	0.13 (0.04,0.23)
SD TOFA PO		6.69 (2.23,20.71)	4.95 (1.94,13.32)	0.23 (0.10,0.39)
SD GOLI SC		8.45 (2.52,28.38)	5.74 (2.18,14.79)	0.28 (0.11,0.51)
SD GOLI IV		6.69 (2.03,21.73)	4.90 (1.84,12.38)	0.23 (0.07,0.47)
SD TOCI IV		5.54 (1.99,15.19)	4.30 (1.81,10.25)	0.20 (0.07,0.38)
SD RITUX IV		2.62 (0.35,14.24)	2.37 (0.36,9.12)	0.08 (‐0.04,0.38)
SD ABA SC		10.22 (1.96,67.26)	6.42 (1.78,21.42)	0.33 (0.07,0.68)
SD CERTO SC		9.52 (2.41,55.12)	6.21 (2.11,20.67)	0.32 (0.09,0.64)
SD ETN SC + MTX		15.43 (6.09,36.84)	8.16 (3.82,17.50)	0.43 (0.27,0.58)
SD INF IV + MTX		11.55 (4.44,28.43)	6.97 (3.19,15.12)	0.36 (0.20,0.53)
SD ABA IV + MTX		14.98 (5.67,38.74)	8.01 (3.80,17.66)	0.42 (0.25,0.60)
SD ADA SC + MTX		23.75 (8.83,64.04)	9.87 (4.67,22.02)	0.54 (0.33,0.71)
SD CERTO SC + MTX/CERTO+ MTX		21.40 (8.90,54.77)	9.45 (4.58,21.00)	0.51 (0.32,0.67)
SD RITUX IV + MTX		9.36 (3.71,24.79)	6.17 (2.85,13.68)	0.31 (0.16,0.49)
SD TOFA PO + MTX		24.16 (8.45,63.98)	9.85 (4.53,22.14)	0.54 (0.35,0.71)
SD GOLI SC + MTX		23.37 (8.62,68.20)	9.78 (4.66,22.22)	0.53 (0.34,0.72)
SD ABA SC + MTX		18.79 (6.14,55.73)	8.88 (3.96,20.29)	0.48 (0.26,0.68)
SD GOLI IV + MTX		8.82 (3.13,25.00)	5.96 (2.52,13.35)	0.29 (0.13,0.51)
SD ANA SC + MTX		10.76 (3.51,34.96)	6.68 (2.78,15.97)	0.35 (0.14,0.58)
SD TOCI IV + MTX		7.72 (2.37,24.38)	5.42 (2.08,13.15)	0.26 (0.09,0.50)
SD CERTO SC + DMARD		5.29 (2.04,14.40)	4.16 (1.83,9.28)	0.19 (0.06,0.40)
SD ADA SC + DMARD		3.17 (1.27,7.97)	2.78 (1.24,5.67)	0.11 (0.01,0.32)
SD ETN SC + DMARD		13.15 (4.43,40.09)	7.44 (3.25,16.84)	0.39 (0.18,0.63)
SD TOCI SC + DMARD		5.09 (2.05,12.60)	3.99 (1.93,7.58)	0.18 (0.04,0.43)
LD ADA SC		3.51 (1.11,11.39)	3.02 (1.10,8.87)	0.12 (0.01,0.26)
LD ETN SC		3.57 (1.35,9.68)	3.07 (1.30,7.43)	0.12 (0.03,0.26)
LD GOLI IV		3.95 (1.07,14.06)	3.33 (1.06,9.32)	0.14 (0.01,0.36)
LD TOCI IV		0.66 (0.12,3.03)	0.67 (0.13,2.77)	‐0.02 (‐0.09,0.08)
LD ADA SC + MTX		17.11 (5.62,50.08)	8.52 (3.75,19.41)	0.45 (0.25,0.66)
LD RITUX IV + MTX		8.19 (3.22,20.68)	5.65 (2.63,12.55)	0.28 (0.13,0.47)
LD ADA IV + MTX		14.37 (2.12,93.58)	7.65 (1.97,22.26)	0.42 (0.06,0.78)
LD ABA IV + MTX		8.07 (2.70,22.51)	5.62 (2.32,12.95)	0.27 (0.11,0.48)
LD ANA SC + MTX		7.55 (1.67,34.99)	5.28 (1.59,14.89)	0.26 (0.04,0.60)
LD CERTO SC + MTX		15.23 (4.36,51.01)	8.03 (3.36,18.78)	0.43 (0.18,0.68)
LD ETN SC + MTX		13.60 (4.08,41.18)	7.57 (3.08,17.26)	0.40 (0.18,0.63)
LD GOLI IV + MTX		7.88 (2.31,27.60)	5.58 (2.03,13.62)	0.27 (0.09,0.53)
LD TOCI IV + MTX		6.21 (2.01,20.21)	4.64 (1.83,11.75)	0.22 (0.06,0.46)
LD TOFA PO + MTX		13.09 (3.10,53.35)	7.35 (2.61,18.10)	0.39 (0.11,0.68)
HD TOCI IV		10.02 (4.58,21.22)	6.44 (3.23,13.55)	0.32 (0.20,0.45)
HD TOFA PO		10.64 (3.51,31.38)	6.67 (2.69,17.25)	0.34 (0.17,0.50)
HD ADA SC		4.92 (1.56,16.41)	3.95 (1.46,11.38)	0.17 (0.05,0.34)
HD ETN SC		7.30 (2.73,21.44)	5.23 (2.30,12.42)	0.25 (0.10,0.47)
HD GOLI SC		9.78 (3.41,28.72)	6.38 (2.68,15.33)	0.32 (0.16,0.52)
HD ABA SC		14.60 (3.02,89.72)	7.82 (2.52,24.97)	0.42 (0.13,0.74)
HD INF IV + MTX		18.86 (7.03,48.19)	8.96 (4.12,19.83)	0.48 (0.29,0.65)
HD TOCI IV + MTX		17.95 (7.14,42.71)	8.77 (4.14,18.85)	0.47 (0.30,0.63)
HD TOFA PO + MTX		19.49 (6.68,52.18)	9.08 (4.03,20.32)	0.48 (0.29,0.67)
HD GOLI SC + MTX		18.31 (6.35,54.48)	8.80 (3.96,20.53)	0.47 (0.27,0.67)
HD CERTO SC + MTX		25.75 (9.86,68.31)	10.24 (4.85,22.45)	0.56 (0.37,0.72)
HD ADA SC + MTX		21.47 (6.23,78.69)	9.39 (4.00,22.26)	0.51 (0.25,0.75)
HD TOCI IV + DMARD		3.74 (1.94,6.85)	3.16 (1.83,5.11)	0.13 (0.04,0.30)
SD ANA SC + SD ETN SC + MTX		9.84 (2.56,36.96)	6.33 (2.21,15.71)	0.32 (0.10,0.60)
SD ANA SC + LD ETN SC + MTX		14.70 (3.90,54.42)	7.81 (2.97,19.10)	0.42 (0.16,0.68)
SD ETN SC	MTX + DMARD	1.23 (0.66,2.37)	1.16 (0.76,1.91)	0.04 (‐0.09,0.16)
SD ADA SC		0.67 (0.28,1.68)	0.74 (0.39,1.50)	‐0.07 (‐0.26,0.08)
SD TOFA PO		1.16 (0.39,3.34)	1.11 (0.52,2.43)	0.03 (‐0.19,0.23)
SD GOLI SC		1.46 (0.48,4.22)	1.29 (0.59,2.64)	0.08 (‐0.15,0.32)
SD GOLI IV		1.15 (0.38,3.37)	1.10 (0.48,2.27)	0.03 (‐0.19,0.26)
SD TOCI IV		0.97 (0.38,2.54)	0.98 (0.47,1.95)	‐0.01 (‐0.19,0.18)
SD RITUX IV		0.45 (0.06,2.33)	0.54 (0.08,1.75)	‐0.12 (‐0.33,0.17)
SD ABA SC		1.81 (0.36,10.65)	1.48 (0.47,4.03)	0.13 (‐0.19,0.51)
SD CERTO SC		1.71 (0.39,8.34)	1.43 (0.51,3.69)	0.11 (‐0.18,0.46)
SD ETN SC + MTX		2.67 (1.63,4.24)	1.83 (1.30,2.72)	0.22 (0.11,0.32)
SD INF IV + MTX		2.00 (1.05,3.70)	1.56 (1.03,2.49)	0.15 (0.01,0.28)
SD ABA IV + MTX		2.61 (1.28,5.27)	1.80 (1.15,2.99)	0.21 (0.06,0.37)
SD ADA SC + MTX		4.11 (1.87,9.46)	2.22 (1.38,3.82)	0.32 (0.14,0.50)
SD CERTO SC + MTX/CERTO+ MTX		3.71 (1.76,7.84)	2.13 (1.36,3.57)	0.30 (0.13,0.46)
SD RITUX IV + MTX		1.62 (0.75,3.65)	1.39 (0.81,2.43)	0.10 (‐0.06,0.28)
SD TOFA PO + MTX		4.17 (1.85,9.68)	2.22 (1.39,3.87)	0.33 (0.14,0.50)
SD GOLI SC + MTX		4.13 (1.65,9.80)	2.22 (1.31,3.91)	0.32 (0.12,0.50)
SD ABA SC + MTX		3.24 (1.27,8.10)	2.00 (1.16,3.54)	0.26 (0.05,0.46)
SD GOLI IV + MTX		1.51 (0.63,3.81)	1.32 (0.73,2.48)	0.08 (‐0.09,0.29)
SD ANA SC + MTX		1.92 (0.67,5.09)	1.53 (0.75,2.85)	0.14 (‐0.08,0.36)
SD TOCI IV + MTX		1.35 (0.45,4.09)	1.23 (0.55,2.57)	0.06 (‐0.15,0.30)
SD CERTO SC + DMARD		0.94 (0.27,3.22)	0.96 (0.37,2.30)	‐0.01 (‐0.25,0.24)
SD ADA SC + DMARD		0.56 (0.15,2.14)	0.63 (0.20,1.73)	‐0.09 (‐0.30,0.14)
SD ETN SC + DMARD		2.27 (0.78,6.68)	1.67 (0.85,3.24)	0.18 (‐0.05,0.43)
SD TOCI SC + DMARD		0.88 (0.23,3.44)	0.91 (0.31,2.25)	‐0.02 (‐0.25,0.27)
LD ADA SC		0.61 (0.21,1.83)	0.68 (0.30,1.61)	‐0.08 (‐0.29,0.11)
LD ETN SC		0.62 (0.28,1.46)	0.70 (0.37,1.36)	‐0.08 (‐0.24,0.06)
LD GOLI IV		0.69 (0.21,2.31)	0.75 (0.28,1.80)	‐0.06 (‐0.26,0.17)
LD TOCI IV		0.12 (0.02,0.51)	0.15 (0.03,0.56)	‐0.22 (‐0.40,‐0.08)
LD ADA SC + MTX		2.88 (1.20,7.42)	1.90 (1.13,3.38)	0.24 (0.04,0.45)
LD RITUX IV + MTX		1.42 (0.65,3.15)	1.27 (0.74,2.21)	0.07 (‐0.09,0.24)
LD ADA IV + MTX		2.62 (0.40,15.12)	1.79 (0.48,4.13)	0.21 (‐0.15,0.58)
LD ABA IV + MTX		1.40 (0.56,3.39)	1.26 (0.67,2.30)	0.07 (‐0.12,0.26)
LD ANA SC + MTX		1.30 (0.30,5.78)	1.20 (0.38,2.85)	0.05 (‐0.19,0.39)
LD CERTO SC + MTX		2.63 (0.91,8.27)	1.80 (0.94,3.44)	0.22 (‐0.02,0.47)
LD ETN SC + MTX		2.36 (0.92,5.64)	1.70 (0.95,2.92)	0.19 (‐0.02,0.39)
LD GOLI IV + MTX		1.37 (0.45,4.14)	1.24 (0.54,2.52)	0.06 (‐0.15,0.30)
LD TOCI IV + MTX		1.09 (0.34,3.27)	1.06 (0.45,2.25)	0.02 (‐0.20,0.25)
LD TOFA PO + MTX		2.25 (0.57,8.33)	1.66 (0.67,3.40)	0.18 (‐0.10,0.47)
HD TOCI IV		1.74 (0.81,3.70)	1.45 (0.88,2.56)	0.12 (‐0.05,0.27)
HD TOFA PO		1.85 (0.61,5.04)	1.51 (0.73,3.04)	0.13 (‐0.11,0.34)
HD ADA SC		0.85 (0.28,2.57)	0.89 (0.40,2.03)	‐0.03 (‐0.24,0.18)
HD ETN SC		1.27 (0.53,3.13)	1.18 (0.65,2.24)	0.05 (‐0.13,0.24)
HD GOLI SC		1.70 (0.67,4.28)	1.42 (0.77,2.71)	0.11 (‐0.09,0.31)
HD ABA SC		2.57 (0.53,14.69)	1.79 (0.65,4.51)	0.21 (‐0.13,0.57)
HD INF IV + MTX		3.24 (1.55,7.05)	2.01 (1.28,3.40)	0.27 (0.10,0.43)
HD TOCI IV + MTX		3.12 (1.42,6.58)	1.97 (1.22,3.35)	0.26 (0.08,0.42)
HD TOFA PO + MTX		3.35 (1.44,7.78)	2.04 (1.23,3.57)	0.27 (0.09,0.46)
HD GOLI SC + MTX		3.20 (1.30,7.77)	1.99 (1.17,3.54)	0.26 (0.06,0.45)
HD CERTO SC + MTX		4.47 (1.96,10.26)	2.28 (1.43,4.03)	0.34 (0.15,0.51)
HD ADA SC + MTX		3.73 (1.27,11.82)	2.11 (1.15,3.91)	0.30 (0.05,0.54)
HD TOCI IV + DMARD		0.65 (0.20,2.05)	0.72 (0.28,1.69)	‐0.07 (‐0.26,0.15)
SD ANA SC + SD ETN SC + MTX		1.69 (0.56,5.21)	1.41 (0.65,2.74)	0.11 (‐0.11,0.38)
SD ANA SC + LD ETN SC + MTX		2.53 (0.87,7.62)	1.76 (0.91,3.26)	0.20 (‐0.03,0.45)
SD ADA SC	SD ETN SC	0.54 (0.26,1.21)	0.63 (0.37,1.15)	‐0.11 (‐0.26,0.03)
SD TOFA PO		0.94 (0.39,2.37)	0.96 (0.51,1.81)	‐0.01 (‐0.20,0.18)
SD GOLI SC		1.19 (0.45,3.22)	1.13 (0.57,2.06)	0.04 (‐0.16,0.27)
SD GOLI IV		0.94 (0.35,2.46)	0.96 (0.44,1.73)	‐0.01 (‐0.19,0.21)
SD TOCI IV		0.80 (0.33,1.87)	0.85 (0.42,1.50)	‐0.04 (‐0.21,0.14)
SD RITUX IV		0.37 (0.05,1.82)	0.46 (0.07,1.45)	‐0.16 (‐0.33,0.14)
SD ABA SC		1.47 (0.32,7.50)	1.28 (0.44,3.01)	0.09 (‐0.21,0.46)
SD CERTO SC		1.39 (0.37,6.41)	1.24 (0.48,2.90)	0.07 (‐0.20,0.42)
SD ETN SC + MTX		2.17 (1.40,3.36)	1.58 (1.23,2.08)	0.18 (0.08,0.29)
SD INF IV + MTX		1.64 (0.92,2.82)	1.36 (0.95,1.89)	0.11 (‐0.02,0.24)
SD ABA IV + MTX		2.12 (1.15,3.75)	1.56 (1.10,2.16)	0.17 (0.03,0.31)
SD ADA SC + MTX		3.31 (1.70,6.75)	1.91 (1.35,2.69)	0.28 (0.12,0.44)
SD CERTO SC + MTX/CERTO+ MTX		3.04 (1.63,5.70)	1.84 (1.34,2.61)	0.26 (0.11,0.41)
SD RITUX IV + MTX		1.32 (0.71,2.58)	1.20 (0.78,1.80)	0.06 (‐0.07,0.22)
SD TOFA PO + MTX		3.40 (1.68,7.11)	1.93 (1.35,2.80)	0.29 (0.12,0.45)
SD GOLI SC + MTX		3.32 (1.58,7.24)	1.91 (1.31,2.84)	0.28 (0.10,0.45)
SD ABA SC + MTX		2.64 (1.14,5.82)	1.73 (1.08,2.55)	0.23 (0.03,0.41)
SD GOLI IV + MTX		1.25 (0.57,2.80)	1.15 (0.67,1.88)	0.05 (‐0.11,0.24)
SD ANA SC + MTX		1.57 (0.61,3.87)	1.34 (0.69,2.14)	0.10 (‐0.10,0.31)
SD TOCI IV + MTX		1.11 (0.38,2.98)	1.07 (0.48,1.95)	0.02 (‐0.18,0.25)
SD CERTO SC + DMARD		0.76 (0.25,2.22)	0.82 (0.35,1.67)	‐0.05 (‐0.25,0.18)
SD ADA SC + DMARD		0.45 (0.13,1.55)	0.54 (0.19,1.34)	‐0.14 (‐0.30,0.09)
SD ETN SC + DMARD		1.85 (0.75,4.62)	1.45 (0.83,2.34)	0.14 (‐0.06,0.36)
SD TOCI SC + DMARD		0.72 (0.21,2.47)	0.79 (0.29,1.73)	‐0.06 (‐0.25,0.21)
LD ADA SC		0.49 (0.19,1.33)	0.59 (0.28,1.23)	‐0.13 (‐0.29,0.05)
LD ETN SC		0.51 (0.27,0.93)	0.61 (0.37,0.95)	‐0.12 (‐0.23,‐0.01)
LD GOLI IV		0.57 (0.18,1.64)	0.66 (0.26,1.38)	‐0.10 (‐0.26,0.10)
LD TOCI IV		0.09 (0.02,0.36)	0.13 (0.03,0.45)	‐0.26 (‐0.39,‐0.14)
LD ADA SC + MTX		2.39 (1.11,5.53)	1.65 (1.07,2.47)	0.20 (0.02,0.40)
LD RITUX IV + MTX		1.17 (0.58,2.22)	1.11 (0.68,1.66)	0.03 (‐0.11,0.18)
LD ADA IV + MTX		2.15 (0.35,11.91)	1.57 (0.44,3.05)	0.18 (‐0.17,0.53)
LD ABA IV + MTX		1.13 (0.52,2.52)	1.09 (0.62,1.74)	0.03 (‐0.12,0.21)
LD ANA SC + MTX		1.07 (0.27,4.40)	1.05 (0.34,2.22)	0.01 (‐0.22,0.35)
LD CERTO SC + MTX		2.15 (0.78,5.93)	1.57 (0.84,2.51)	0.18 (‐0.05,0.41)
LD ETN SC + MTX		1.92 (0.79,4.40)	1.48 (0.85,2.26)	0.15 (‐0.05,0.35)
LD GOLI IV + MTX		1.11 (0.40,3.11)	1.07 (0.50,1.95)	0.02 (‐0.17,0.27)
LD TOCI IV + MTX		0.88 (0.31,2.38)	0.92 (0.40,1.72)	‐0.03 (‐0.21,0.20)
LD TOFA PO + MTX		1.87 (0.52,6.29)	1.46 (0.61,2.61)	0.14 (‐0.12,0.42)
HD TOCI IV		1.41 (0.79,2.48)	1.25 (0.86,1.82)	0.08 (‐0.05,0.21)
HD TOFA PO		1.52 (0.60,3.60)	1.31 (0.71,2.27)	0.09 (‐0.11,0.29)
HD ADA SC		0.69 (0.28,1.87)	0.76 (0.40,1.56)	‐0.07 (‐0.25,0.13)
HD ETN SC		1.04 (0.53,2.06)	1.03 (0.63,1.57)	0.01 (‐0.12,0.17)
HD GOLI SC		1.38 (0.63,3.12)	1.23 (0.72,2.01)	0.07 (‐0.10,0.26)
HD ABA SC		2.11 (0.46,10.73)	1.56 (0.58,3.37)	0.17 (‐0.16,0.52)
HD INF IV + MTX		2.66 (1.38,5.23)	1.74 (1.21,2.50)	0.23 (0.07,0.38)
HD TOCI IV + MTX		2.51 (1.36,4.86)	1.70 (1.20,2.49)	0.22 (0.07,0.36)
HD TOFA PO + MTX		2.73 (1.35,5.74)	1.76 (1.21,2.59)	0.23 (0.07,0.40)
HD GOLI SC + MTX		2.60 (1.22,5.76)	1.72 (1.14,2.58)	0.22 (0.04,0.41)
HD CERTO SC + MTX		3.63 (1.87,7.36)	1.98 (1.42,2.86)	0.31 (0.14,0.45)
HD ADA SC + MTX		3.03 (1.06,8.85)	1.84 (1.03,2.87)	0.26 (0.01,0.48)
HD TOCI IV + DMARD		0.52 (0.19,1.50)	0.62 (0.26,1.31)	‐0.11 (‐0.27,0.09)
SD ANA SC + SD ETN SC + MTX		1.36 (0.47,4.22)	1.22 (0.57,2.16)	0.07 (‐0.14,0.34)
SD ANA SC + LD ETN SC + MTX		2.05 (0.69,5.80)	1.53 (0.77,2.52)	0.17 (‐0.07,0.40)
SD TOFA PO	SD ADA SC	1.73 (0.80,3.81)	1.51 (0.85,2.66)	0.10 (‐0.04,0.26)
SD GOLI SC		2.16 (0.74,6.48)	1.75 (0.78,3.50)	0.15 (‐0.05,0.39)
SD GOLI IV		1.73 (0.54,5.57)	1.51 (0.61,3.22)	0.10 (‐0.09,0.35)
SD TOCI IV		1.46 (0.57,3.69)	1.34 (0.63,2.60)	0.07 (‐0.09,0.26)
SD RITUX IV		0.67 (0.08,3.59)	0.72 (0.09,2.47)	‐0.05 (‐0.20,0.26)
SD ABA SC		2.74 (0.62,13.53)	2.03 (0.68,4.74)	0.20 (‐0.07,0.55)
SD CERTO SC		2.59 (0.71,10.10)	1.98 (0.76,4.10)	0.19 (‐0.06,0.50)
SD ETN SC + MTX		3.97 (1.77,8.94)	2.49 (1.47,4.16)	0.29 (0.12,0.47)
SD INF IV + MTX		3.00 (1.21,7.15)	2.13 (1.16,3.72)	0.22 (0.04,0.42)
SD ABA IV + MTX		3.88 (1.60,9.17)	2.46 (1.40,4.19)	0.29 (0.09,0.47)
SD ADA SC + MTX		6.24 (2.30,15.44)	3.04 (1.70,4.99)	0.41 (0.17,0.58)
SD CERTO SC + MTX/CERTO+ MTX		5.69 (2.20,14.03)	2.92 (1.70,4.87)	0.38 (0.16,0.56)
SD RITUX IV + MTX		2.46 (0.94,5.83)	1.91 (0.95,3.29)	0.18 (‐0.01,0.37)
SD TOFA PO + MTX		6.34 (2.41,15.58)	3.06 (1.76,4.98)	0.41 (0.19,0.59)
SD GOLI SC + MTX		6.17 (2.25,17.16)	3.03 (1.73,5.10)	0.40 (0.17,0.60)
SD ABA SC + MTX		4.84 (1.63,13.02)	2.74 (1.41,4.62)	0.34 (0.10,0.55)
SD GOLI IV + MTX		2.29 (0.81,6.37)	1.82 (0.85,3.44)	0.16 (‐0.03,0.39)
SD ANA SC + MTX		2.90 (0.91,8.36)	2.10 (0.93,3.88)	0.22 (‐0.02,0.46)
SD TOCI IV + MTX		2.01 (0.67,6.11)	1.67 (0.72,3.44)	0.13 (‐0.06,0.39)
SD CERTO SC + DMARD		1.37 (0.47,4.26)	1.27 (0.53,2.75)	0.05 (‐0.11,0.29)
SD ADA SC + DMARD		0.83 (0.20,3.18)	0.86 (0.24,2.33)	‐0.03 (‐0.18,0.22)
SD ETN SC + DMARD		3.42 (1.09,10.90)	2.31 (1.06,4.23)	0.26 (0.01,0.51)
SD TOCI SC + DMARD		1.32 (0.33,5.23)	1.25 (0.39,3.03)	0.05 (‐0.14,0.35)
LD ADA SC		0.91 (0.44,1.87)	0.92 (0.50,1.63)	‐0.01 (‐0.11,0.11)
LD ETN SC		0.94 (0.37,2.19)	0.95 (0.44,1.85)	‐0.01 (‐0.14,0.14)
LD GOLI IV		1.03 (0.29,3.53)	1.03 (0.35,2.47)	0.01 (‐0.15,0.25)
LD TOCI IV		0.18 (0.03,0.73)	0.21 (0.04,0.76)	‐0.15 (‐0.25,‐0.04)
LD ADA SC + MTX		4.38 (1.60,12.11)	2.63 (1.40,4.53)	0.32 (0.10,0.54)
LD RITUX IV + MTX		2.15 (0.81,5.17)	1.74 (0.85,3.15)	0.15 (‐0.04,0.34)
LD ADA IV + MTX		3.98 (0.57,20.80)	2.50 (0.63,4.94)	0.29 (‐0.08,0.63)
LD ABA IV + MTX		2.09 (0.73,5.57)	1.72 (0.78,3.24)	0.14 (‐0.05,0.36)
LD ANA SC + MTX		1.93 (0.41,8.78)	1.63 (0.47,3.77)	0.12 (‐0.11,0.47)
LD CERTO SC + MTX		3.97 (1.19,13.41)	2.50 (1.13,4.56)	0.29 (0.03,0.56)
LD ETN SC + MTX		3.49 (1.19,10.53)	2.34 (1.14,4.20)	0.26 (0.03,0.52)
LD GOLI IV + MTX		2.02 (0.65,6.88)	1.67 (0.71,3.59)	0.13 (‐0.06,0.41)
LD TOCI IV + MTX		1.63 (0.51,4.73)	1.45 (0.57,3.02)	0.09 (‐0.10,0.32)
LD TOFA PO + MTX		3.39 (0.77,13.20)	2.30 (0.81,4.47)	0.26 (‐0.04,0.56)
HD TOCI IV		2.61 (1.25,5.23)	1.98 (1.18,3.19)	0.19 (0.04,0.34)
HD TOFA PO		2.75 (1.23,5.94)	2.05 (1.17,3.40)	0.20 (0.04,0.37)
HD ADA SC		1.28 (0.63,2.69)	1.21 (0.69,2.09)	0.04 (‐0.07,0.19)
HD ETN SC		1.93 (0.72,5.18)	1.63 (0.77,3.17)	0.12 (‐0.05,0.34)
HD GOLI SC		2.56 (0.98,6.77)	1.94 (0.98,3.62)	0.19 (0.00,0.40)
HD ABA SC		3.84 (0.91,19.43)	2.44 (0.94,5.29)	0.28 (‐0.02,0.62)
HD INF IV + MTX		4.86 (1.92,12.96)	2.74 (1.57,4.72)	0.34 (0.13,0.55)
HD TOCI IV + MTX		4.65 (1.91,10.77)	2.70 (1.56,4.51)	0.33 (0.13,0.51)
HD TOFA PO + MTX		5.09 (1.99,12.40)	2.81 (1.58,4.58)	0.35 (0.14,0.54)
HD GOLI SC + MTX		4.81 (1.72,13.21)	2.73 (1.46,4.72)	0.34 (0.11,0.55)
HD CERTO SC + MTX		6.80 (2.61,16.93)	3.14 (1.85,5.20)	0.42 (0.20,0.60)
HD ADA SC + MTX		5.60 (1.70,19.32)	2.92 (1.47,5.02)	0.38 (0.10,0.62)
HD TOCI IV + DMARD		0.97 (0.30,3.08)	0.98 (0.36,2.26)	0.00 (‐0.15,0.22)
SD ANA SC + SD ETN SC + MTX		2.57 (0.75,9.10)	1.94 (0.80,3.91)	0.19 (‐0.05,0.47)
SD ANA SC + LD ETN SC + MTX		3.84 (1.10,12.87)	2.46 (1.08,4.53)	0.28 (0.02,0.55)
SD GOLI SC	SD TOFA PO	1.28 (0.39,3.96)	1.18 (0.51,2.41)	0.05 (‐0.19,0.31)
SD GOLI IV		1.00 (0.28,3.34)	1.00 (0.38,2.20)	0.00 (‐0.23,0.27)
SD TOCI IV		0.83 (0.26,2.48)	0.88 (0.37,1.86)	‐0.04 (‐0.25,0.19)
SD RITUX IV		0.39 (0.04,2.29)	0.48 (0.06,1.74)	‐0.15 (‐0.36,0.17)
SD ABA SC		1.58 (0.33,8.35)	1.34 (0.44,3.11)	0.10 (‐0.21,0.48)
SD CERTO SC		1.51 (0.38,6.32)	1.31 (0.50,2.84)	0.09 (‐0.19,0.42)
SD ETN SC + MTX		2.31 (0.88,6.26)	1.66 (0.93,3.01)	0.19 (‐0.03,0.41)
SD INF IV + MTX		1.72 (0.62,4.76)	1.41 (0.73,2.69)	0.12 (‐0.11,0.35)
SD ABA IV + MTX		2.24 (0.80,6.24)	1.63 (0.86,3.03)	0.19 (‐0.05,0.41)
SD ADA SC + MTX		3.55 (1.17,10.48)	2.01 (1.10,3.61)	0.30 (0.04,0.52)
SD CERTO SC + MTX/CERTO+ MTX		3.21 (1.12,9.16)	1.92 (1.07,3.46)	0.28 (0.03,0.50)
SD RITUX IV + MTX		1.42 (0.46,3.90)	1.26 (0.59,2.42)	0.08 (‐0.16,0.30)
SD TOFA PO + MTX		3.60 (1.19,10.34)	2.02 (1.11,3.62)	0.30 (0.04,0.52)
SD GOLI SC + MTX		3.58 (1.17,10.70)	2.01 (1.09,3.64)	0.30 (0.04,0.52)
SD ABA SC + MTX		2.78 (0.88,8.76)	1.81 (0.92,3.33)	0.24 (‐0.03,0.49)
SD GOLI IV + MTX		1.31 (0.42,4.18)	1.19 (0.54,2.50)	0.06 (‐0.18,0.32)
SD ANA SC + MTX		1.64 (0.51,5.60)	1.36 (0.62,2.80)	0.11 (‐0.14,0.39)
SD TOCI IV + MTX		1.17 (0.33,4.14)	1.11 (0.44,2.43)	0.03 (‐0.21,0.32)
SD CERTO SC + DMARD		0.79 (0.24,2.75)	0.85 (0.35,1.98)	‐0.04 (‐0.26,0.22)
SD ADA SC + DMARD		0.47 (0.11,2.03)	0.56 (0.16,1.63)	‐0.13 (‐0.33,0.15)
SD ETN SC + DMARD		1.95 (0.56,7.17)	1.52 (0.68,3.07)	0.15 (‐0.13,0.44)
SD TOCI SC + DMARD		0.77 (0.18,3.11)	0.83 (0.25,2.09)	‐0.05 (‐0.28,0.25)
LD ADA SC		0.52 (0.20,1.40)	0.61 (0.29,1.29)	‐0.11 (‐0.29,0.06)
LD ETN SC		0.54 (0.19,1.54)	0.63 (0.28,1.37)	‐0.11 (‐0.29,0.08)
LD GOLI IV		0.59 (0.15,2.28)	0.68 (0.22,1.74)	‐0.09 (‐0.31,0.17)
LD TOCI IV		0.10 (0.01,0.46)	0.14 (0.02,0.53)	‐0.25 (‐0.41,‐0.10)
LD ADA SC + MTX		2.57 (0.85,8.46)	1.74 (0.90,3.31)	0.22 (‐0.04,0.48)
LD RITUX IV + MTX		1.24 (0.40,3.55)	1.16 (0.52,2.31)	0.05 (‐0.18,0.28)
LD ADA IV + MTX		2.27 (0.32,14.64)	1.64 (0.43,3.55)	0.19 (‐0.20,0.57)
LD ABA IV + MTX		1.21 (0.37,3.79)	1.14 (0.50,2.34)	0.04 (‐0.19,0.30)
LD ANA SC + MTX		1.12 (0.22,5.62)	1.08 (0.31,2.73)	0.02 (‐0.25,0.40)
LD CERTO SC + MTX		2.25 (0.63,9.29)	1.62 (0.73,3.32)	0.19 (‐0.10,0.50)
LD ETN SC + MTX		2.03 (0.62,7.04)	1.55 (0.72,3.06)	0.16 (‐0.10,0.44)
LD GOLI IV + MTX		1.17 (0.32,4.45)	1.11 (0.43,2.48)	0.03 (‐0.21,0.33)
LD TOCI IV + MTX		0.94 (0.26,3.11)	0.96 (0.36,2.11)	‐0.01 (‐0.24,0.25)
LD TOFA PO + MTX		1.95 (0.43,8.36)	1.52 (0.52,3.23)	0.15 (‐0.16,0.48)
HD TOCI IV		1.49 (0.60,3.77)	1.30 (0.71,2.41)	0.09 (‐0.12,0.29)
HD TOFA PO		1.59 (0.88,2.79)	1.35 (0.92,1.97)	0.10 (‐0.03,0.23)
HD ADA SC		0.74 (0.27,2.01)	0.80 (0.38,1.65)	‐0.06 (‐0.25,0.14)
HD ETN SC		1.09 (0.37,3.48)	1.06 (0.49,2.27)	0.02 (‐0.19,0.27)
HD GOLI SC		1.49 (0.49,4.16)	1.30 (0.61,2.50)	0.09 (‐0.15,0.32)
HD ABA SC		2.25 (0.47,11.73)	1.63 (0.60,3.46)	0.19 (‐0.15,0.54)
HD INF IV + MTX		2.79 (0.94,8.38)	1.80 (0.96,3.31)	0.24 (‐0.01,0.48)
HD TOCI IV + MTX		2.70 (1.00,7.10)	1.77 (1.00,3.19)	0.23 (0.00,0.44)
HD TOFA PO + MTX		2.92 (1.00,8.04)	1.84 (1.00,3.29)	0.25 (0.00,0.47)
HD GOLI SC + MTX		2.76 (0.89,8.24)	1.80 (0.93,3.29)	0.24 (‐0.03,0.47)
HD CERTO SC + MTX		3.88 (1.33,11.44)	2.07 (1.18,3.68)	0.32 (0.07,0.54)
HD ADA SC + MTX		3.20 (0.82,13.02)	1.91 (0.88,3.63)	0.27 (‐0.05,0.56)
HD TOCI IV + DMARD		0.56 (0.15,2.04)	0.65 (0.22,1.67)	‐0.10 (‐0.31,0.15)
SD ANA SC + SD ETN SC + MTX		1.47 (0.37,6.12)	1.29 (0.49,2.85)	0.09 (‐0.19,0.41)
SD ANA SC + LD ETN SC + MTX		2.15 (0.57,8.30)	1.59 (0.67,3.30)	0.18 (‐0.12,0.48)
SD GOLI IV	SD GOLI SC	0.79 (0.27,2.32)	0.86 (0.40,1.74)	‐0.05 (‐0.27,0.18)
SD TOCI IV		0.66 (0.21,2.27)	0.75 (0.34,1.81)	‐0.09 (‐0.34,0.16)
SD RITUX IV		0.31 (0.04,1.82)	0.41 (0.06,1.50)	‐0.19 (‐0.45,0.12)
SD ABA SC		1.23 (0.23,7.46)	1.14 (0.37,3.15)	0.05 (‐0.31,0.46)
SD CERTO SC		1.17 (0.27,5.93)	1.11 (0.42,2.89)	0.04 (‐0.29,0.40)
SD ETN SC + MTX		1.83 (0.66,5.08)	1.42 (0.80,2.76)	0.14 (‐0.10,0.36)
SD INF IV + MTX		1.38 (0.48,3.74)	1.21 (0.65,2.39)	0.07 (‐0.17,0.29)
SD ABA IV + MTX		1.81 (0.63,4.85)	1.40 (0.78,2.69)	0.14 (‐0.11,0.36)
SD ADA SC + MTX		2.82 (0.93,8.79)	1.71 (0.96,3.35)	0.24 (‐0.02,0.49)
SD CERTO SC + MTX/CERTO+ MTX		2.60 (0.90,7.38)	1.65 (0.95,3.25)	0.22 (‐0.03,0.45)
SD RITUX IV + MTX		1.12 (0.38,3.30)	1.07 (0.55,2.20)	0.02 (‐0.22,0.26)
SD TOFA PO + MTX		2.85 (0.96,8.93)	1.72 (0.98,3.43)	0.25 (‐0.01,0.49)
SD GOLI SC + MTX		2.81 (1.00,8.35)	1.71 (1.00,3.33)	0.24 (0.00,0.48)
SD ABA SC + MTX		2.22 (0.68,7.31)	1.55 (0.81,3.11)	0.19 (‐0.09,0.45)
SD GOLI IV + MTX		1.05 (0.36,3.21)	1.03 (0.51,2.15)	0.01 (‐0.23,0.25)
SD ANA SC + MTX		1.31 (0.35,4.50)	1.18 (0.52,2.57)	0.06 (‐0.23,0.34)
SD TOCI IV + MTX		0.93 (0.24,3.45)	0.96 (0.37,2.25)	‐0.02 (‐0.31,0.28)
SD CERTO SC + DMARD		0.64 (0.17,2.49)	0.74 (0.29,1.85)	‐0.09 (‐0.37,0.19)
SD ADA SC + DMARD		0.37 (0.08,1.82)	0.48 (0.14,1.52)	‐0.17 (‐0.43,0.12)
SD ETN SC + DMARD		1.57 (0.42,6.01)	1.30 (0.58,2.82)	0.10 (‐0.20,0.41)
SD TOCI SC + DMARD		0.61 (0.13,2.73)	0.71 (0.22,1.87)	‐0.10 (‐0.37,0.21)
LD ADA SC		0.41 (0.13,1.46)	0.52 (0.23,1.33)	‐0.16 (‐0.42,0.06)
LD ETN SC		0.43 (0.14,1.26)	0.54 (0.26,1.19)	‐0.16 (‐0.39,0.04)
LD GOLI IV		0.48 (0.13,1.70)	0.59 (0.22,1.45)	‐0.14 (‐0.38,0.11)
LD TOCI IV		0.08 (0.01,0.41)	0.12 (0.02,0.49)	‐0.30 (‐0.53,‐0.11)
LD ADA SC + MTX		2.00 (0.62,6.80)	1.47 (0.77,3.04)	0.16 (‐0.11,0.43)
LD RITUX IV + MTX		0.99 (0.32,2.88)	0.99 (0.49,2.06)	0.00 (‐0.26,0.23)
LD ADA IV + MTX		1.79 (0.24,12.52)	1.39 (0.34,3.44)	0.13 (‐0.27,0.55)
LD ABA IV + MTX		0.97 (0.31,2.94)	0.98 (0.46,2.08)	‐0.01 (‐0.27,0.24)
LD ANA SC + MTX		0.91 (0.17,4.98)	0.94 (0.27,2.51)	‐0.02 (‐0.34,0.36)
LD CERTO SC + MTX		1.81 (0.47,7.41)	1.40 (0.63,3.14)	0.14 (‐0.17,0.45)
LD ETN SC + MTX		1.61 (0.48,5.33)	1.32 (0.64,2.73)	0.11 (‐0.17,0.38)
LD GOLI IV + MTX		0.94 (0.29,3.21)	0.96 (0.42,2.09)	‐0.01 (‐0.26,0.27)
LD TOCI IV + MTX		0.74 (0.20,2.81)	0.81 (0.32,2.03)	‐0.06 (‐0.33,0.22)
LD TOFA PO + MTX		1.58 (0.33,6.53)	1.30 (0.48,2.88)	0.10 (‐0.23,0.43)
HD TOCI IV		1.20 (0.41,3.21)	1.12 (0.60,2.24)	0.04 (‐0.21,0.25)
HD TOFA PO		1.26 (0.41,4.19)	1.15 (0.59,2.63)	0.05 (‐0.22,0.30)
HD ADA SC		0.58 (0.18,2.03)	0.69 (0.31,1.68)	‐0.11 (‐0.37,0.14)
HD ETN SC		0.87 (0.28,2.82)	0.91 (0.44,2.00)	‐0.03 (‐0.28,0.23)
HD GOLI SC		1.18 (0.48,2.78)	1.10 (0.64,1.98)	0.04 (‐0.17,0.22)
HD ABA SC		1.76 (0.34,10.96)	1.38 (0.50,3.52)	0.13 (‐0.25,0.52)
HD INF IV + MTX		2.25 (0.72,6.53)	1.56 (0.84,3.12)	0.19 (‐0.08,0.42)
HD TOCI IV + MTX		2.13 (0.73,6.30)	1.52 (0.85,3.04)	0.18 (‐0.08,0.41)
HD TOFA PO + MTX		2.28 (0.77,7.15)	1.57 (0.87,3.11)	0.20 (‐0.06,0.44)
HD GOLI SC + MTX		2.16 (0.72,6.83)	1.52 (0.84,3.02)	0.18 (‐0.08,0.44)
HD CERTO SC + MTX		3.09 (1.03,9.34)	1.78 (1.01,3.48)	0.27 (0.01,0.49)
HD ADA SC + MTX		2.52 (0.70,9.68)	1.63 (0.81,3.35)	0.22 (‐0.09,0.51)
HD TOCI IV + DMARD		0.44 (0.11,1.76)	0.55 (0.20,1.47)	‐0.15 (‐0.41,0.11)
SD ANA SC + SD ETN SC + MTX		1.16 (0.27,4.95)	1.10 (0.42,2.57)	0.03 (‐0.28,0.36)
SD ANA SC + LD ETN SC + MTX		1.79 (0.40,7.49)	1.38 (0.56,3.08)	0.13 (‐0.20,0.45)
SD TOCI IV	SD GOLI IV	0.83 (0.26,2.80)	0.87 (0.39,2.13)	‐0.04 (‐0.29,0.19)
SD RITUX IV		0.39 (0.05,2.29)	0.48 (0.07,1.73)	‐0.14 (‐0.40,0.16)
SD ABA SC		1.63 (0.26,9.41)	1.37 (0.40,3.98)	0.10 (‐0.27,0.49)
SD CERTO SC		1.48 (0.32,8.09)	1.29 (0.46,3.71)	0.09 (‐0.24,0.44)
SD ETN SC + MTX		2.28 (0.88,6.42)	1.64 (0.94,3.63)	0.19 (‐0.03,0.39)
SD INF IV + MTX		1.70 (0.67,4.67)	1.40 (0.79,2.89)	0.12 (‐0.10,0.33)
SD ABA IV + MTX		2.24 (0.87,6.17)	1.63 (0.93,3.39)	0.18 (‐0.03,0.39)
SD ADA SC + MTX		3.55 (1.26,10.41)	1.99 (1.12,4.15)	0.29 (0.06,0.51)
SD CERTO SC + MTX/CERTO+ MTX		3.21 (1.20,8.69)	1.92 (1.09,4.00)	0.27 (0.04,0.47)
SD RITUX IV + MTX		1.41 (0.50,4.00)	1.26 (0.65,2.66)	0.07 (‐0.16,0.28)
SD TOFA PO + MTX		3.55 (1.29,10.77)	2.00 (1.12,4.38)	0.29 (0.06,0.51)
SD GOLI SC + MTX		3.56 (1.23,10.36)	1.99 (1.11,4.27)	0.29 (0.05,0.51)
SD ABA SC + MTX		2.72 (0.91,9.50)	1.79 (0.94,3.99)	0.23 (‐0.02,0.49)
SD GOLI IV + MTX		1.31 (0.54,3.34)	1.19 (0.68,2.33)	0.06 (‐0.13,0.25)
SD ANA SC + MTX		1.67 (0.49,5.35)	1.37 (0.64,3.00)	0.11 (‐0.16,0.36)
SD TOCI IV + MTX		1.19 (0.31,4.64)	1.12 (0.44,2.77)	0.03 (‐0.24,0.32)
SD CERTO SC + DMARD		0.79 (0.20,3.39)	0.85 (0.32,2.40)	‐0.04 (‐0.33,0.24)
SD ADA SC + DMARD		0.48 (0.11,2.21)	0.58 (0.17,1.78)	‐0.12 (‐0.39,0.15)
SD ETN SC + DMARD		1.96 (0.55,7.94)	1.51 (0.68,3.70)	0.15 (‐0.13,0.44)
SD TOCI SC + DMARD		0.79 (0.17,3.47)	0.84 (0.25,2.36)	‐0.04 (‐0.33,0.26)
LD ADA SC		0.52 (0.14,1.85)	0.61 (0.25,1.66)	‐0.11 (‐0.38,0.10)
LD ETN SC		0.54 (0.19,1.60)	0.63 (0.30,1.47)	‐0.11 (‐0.33,0.07)
LD GOLI IV		0.59 (0.21,1.72)	0.68 (0.29,1.48)	‐0.09 (‐0.29,0.10)
LD TOCI IV		0.10 (0.02,0.49)	0.14 (0.03,0.56)	‐0.25 (‐0.49,‐0.07)
LD ADA SC + MTX		2.49 (0.83,7.83)	1.72 (0.90,3.79)	0.21 (‐0.04,0.45)
LD RITUX IV + MTX		1.24 (0.43,3.66)	1.16 (0.59,2.45)	0.04 (‐0.19,0.26)
LD ADA IV + MTX		2.30 (0.30,14.83)	1.62 (0.41,4.17)	0.18 (‐0.23,0.57)
LD ABA IV + MTX		1.21 (0.41,3.57)	1.13 (0.56,2.47)	0.04 (‐0.19,0.26)
LD ANA SC + MTX		1.12 (0.23,5.89)	1.07 (0.34,2.99)	0.02 (‐0.27,0.39)
LD CERTO SC + MTX		2.26 (0.63,8.62)	1.62 (0.75,3.71)	0.18 (‐0.10,0.47)
LD ETN SC + MTX		2.03 (0.63,7.01)	1.53 (0.76,3.42)	0.16 (‐0.10,0.41)
LD GOLI IV + MTX		1.18 (0.46,3.15)	1.12 (0.57,2.25)	0.03 (‐0.16,0.25)
LD TOCI IV + MTX		0.94 (0.26,3.34)	0.96 (0.38,2.39)	‐0.01 (‐0.27,0.25)
LD TOFA PO + MTX		2.02 (0.44,8.07)	1.51 (0.56,3.52)	0.15 (‐0.17,0.46)
HD TOCI IV		1.50 (0.54,4.28)	1.30 (0.71,2.87)	0.09 (‐0.14,0.29)
HD TOFA PO		1.60 (0.48,5.54)	1.36 (0.65,3.33)	0.10 (‐0.17,0.34)
HD ADA SC		0.73 (0.21,2.66)	0.80 (0.34,2.12)	‐0.06 (‐0.33,0.17)
HD ETN SC		1.09 (0.37,3.65)	1.06 (0.52,2.44)	0.02 (‐0.22,0.26)
HD GOLI SC		1.47 (0.51,4.28)	1.29 (0.67,2.79)	0.08 (‐0.15,0.30)
HD ABA SC		2.28 (0.36,13.60)	1.62 (0.52,4.64)	0.18 (‐0.22,0.56)
HD INF IV + MTX		2.77 (1.02,8.60)	1.80 (1.01,3.88)	0.23 (0.01,0.46)
HD TOCI IV + MTX		2.69 (0.97,7.55)	1.78 (0.99,3.80)	0.23 (‐0.01,0.44)
HD TOFA PO + MTX		2.88 (1.00,8.48)	1.83 (1.00,3.88)	0.24 (0.00,0.47)
HD GOLI SC + MTX		2.74 (0.95,8.32)	1.78 (0.97,3.84)	0.23 (‐0.01,0.47)
HD CERTO SC + MTX		3.91 (1.39,11.12)	2.06 (1.18,4.46)	0.31 (0.08,0.52)
HD ADA SC + MTX		3.20 (0.89,12.30)	1.90 (0.93,4.33)	0.26 (‐0.03,0.54)
HD TOCI IV + DMARD		0.55 (0.14,2.36)	0.64 (0.23,1.86)	‐0.10 (‐0.36,0.15)
SD ANA SC + SD ETN SC + MTX		1.46 (0.38,6.28)	1.28 (0.50,3.21)	0.08 (‐0.21,0.40)
SD ANA SC + LD ETN SC + MTX		2.17 (0.55,8.79)	1.59 (0.66,3.83)	0.18 (‐0.13,0.47)
SD RITUX IV	SD TOCI IV	0.45 (0.06,2.62)	0.54 (0.08,1.98)	‐0.12 (‐0.33,0.20)
SD ABA SC		1.83 (0.36,11.86)	1.48 (0.46,4.33)	0.13 (‐0.20,0.53)
SD CERTO SC		1.75 (0.41,9.08)	1.45 (0.52,3.98)	0.12 (‐0.18,0.47)
SD ETN SC + MTX		2.71 (1.13,6.78)	1.86 (1.08,3.65)	0.22 (0.03,0.40)
SD INF IV + MTX		2.07 (0.83,5.17)	1.60 (0.89,3.10)	0.16 (‐0.04,0.34)
SD ABA IV + MTX		2.66 (1.08,6.74)	1.83 (1.05,3.55)	0.22 (0.02,0.41)
SD ADA SC + MTX		4.19 (1.58,11.07)	2.25 (1.29,4.30)	0.32 (0.11,0.53)
SD CERTO SC + MTX/CERTO+ MTX		3.84 (1.57,9.46)	2.17 (1.27,4.19)	0.31 (0.10,0.49)
SD RITUX IV + MTX		1.67 (0.63,4.23)	1.42 (0.73,2.79)	0.11 (‐0.09,0.30)
SD TOFA PO + MTX		4.31 (1.65,11.31)	2.27 (1.30,4.39)	0.33 (0.12,0.52)
SD GOLI SC + MTX		4.24 (1.56,11.54)	2.27 (1.29,4.37)	0.33 (0.10,0.53)
SD ABA SC + MTX		3.33 (1.10,9.34)	2.05 (1.06,3.99)	0.27 (0.02,0.49)
SD GOLI IV + MTX		1.58 (0.54,4.50)	1.36 (0.65,2.81)	0.09 (‐0.13,0.32)
SD ANA SC + MTX		1.98 (0.63,5.86)	1.56 (0.72,3.19)	0.14 (‐0.10,0.39)
SD TOCI IV + MTX		1.40 (0.50,3.81)	1.25 (0.60,2.54)	0.07 (‐0.14,0.29)
SD CERTO SC + DMARD		0.95 (0.28,3.40)	0.96 (0.39,2.42)	‐0.01 (‐0.24,0.24)
SD ADA SC + DMARD		0.56 (0.14,2.34)	0.64 (0.20,1.82)	‐0.09 (‐0.30,0.16)
SD ETN SC + DMARD		2.36 (0.67,8.14)	1.72 (0.76,3.69)	0.19 (‐0.08,0.46)
SD TOCI SC + DMARD		0.90 (0.23,3.50)	0.92 (0.31,2.34)	‐0.02 (‐0.24,0.26)
LD ADA SC		0.62 (0.21,2.00)	0.69 (0.30,1.73)	‐0.08 (‐0.28,0.11)
LD ETN SC		0.65 (0.24,1.74)	0.71 (0.35,1.55)	‐0.07 (‐0.26,0.09)
LD GOLI IV		0.71 (0.18,2.55)	0.77 (0.25,1.98)	‐0.06 (‐0.27,0.18)
LD TOCI IV		0.12 (0.02,0.49)	0.16 (0.03,0.56)	‐0.21 (‐0.39,‐0.08)
LD ADA SC + MTX		3.01 (1.09,8.51)	1.94 (1.06,3.83)	0.25 (0.02,0.46)
LD RITUX IV + MTX		1.46 (0.56,3.80)	1.29 (0.67,2.59)	0.08 (‐0.12,0.27)
LD ADA IV + MTX		2.72 (0.38,15.97)	1.84 (0.47,4.52)	0.22 (‐0.16,0.59)
LD ABA IV + MTX		1.44 (0.51,3.84)	1.28 (0.61,2.59)	0.07 (‐0.14,0.29)
LD ANA SC + MTX		1.33 (0.29,6.67)	1.21 (0.39,3.19)	0.06 (‐0.21,0.42)
LD CERTO SC + MTX		2.71 (0.81,8.99)	1.85 (0.86,3.92)	0.22 (‐0.05,0.48)
LD ETN SC + MTX		2.42 (0.75,7.25)	1.74 (0.82,3.62)	0.19 (‐0.06,0.43)
LD GOLI IV + MTX		1.40 (0.40,4.77)	1.27 (0.52,2.90)	0.07 (‐0.18,0.34)
LD TOCI IV + MTX		1.12 (0.39,3.10)	1.08 (0.49,2.23)	0.02 (‐0.17,0.24)
LD TOFA PO + MTX		2.34 (0.53,9.11)	1.71 (0.64,3.72)	0.19 (‐0.12,0.49)
HD TOCI IV		1.79 (0.85,3.71)	1.48 (0.91,2.63)	0.12 (‐0.04,0.26)
HD TOFA PO		1.91 (0.63,5.76)	1.53 (0.75,3.39)	0.14 (‐0.10,0.35)
HD ADA SC		0.88 (0.29,2.73)	0.91 (0.40,2.16)	‐0.02 (‐0.24,0.18)
HD ETN SC		1.29 (0.46,4.11)	1.20 (0.57,2.74)	0.05 (‐0.16,0.29)
HD GOLI SC		1.75 (0.59,4.93)	1.46 (0.71,3.02)	0.12 (‐0.11,0.33)
HD ABA SC		2.61 (0.48,16.78)	1.80 (0.61,5.00)	0.21 (‐0.15,0.59)
HD INF IV + MTX		3.35 (1.30,8.69)	2.04 (1.17,3.95)	0.27 (0.06,0.47)
HD TOCI IV + MTX		3.21 (1.43,7.28)	2.00 (1.23,3.67)	0.26 (0.09,0.43)
HD TOFA PO + MTX		3.44 (1.27,9.02)	2.07 (1.15,4.09)	0.28 (0.06,0.48)
HD GOLI SC + MTX		3.33 (1.18,9.47)	2.03 (1.10,4.00)	0.27 (0.04,0.49)
HD CERTO SC + MTX		4.62 (1.78,11.81)	2.33 (1.35,4.50)	0.35 (0.14,0.54)
HD ADA SC + MTX		3.85 (1.10,12.74)	2.16 (1.06,4.37)	0.30 (0.02,0.55)
HD TOCI IV + DMARD		0.66 (0.21,2.26)	0.72 (0.28,1.82)	‐0.07 (‐0.27,0.16)
SD ANA SC + SD ETN SC + MTX		1.74 (0.48,6.36)	1.46 (0.59,3.25)	0.12 (‐0.14,0.41)
SD ANA SC + LD ETN SC + MTX		2.63 (0.69,9.59)	1.82 (0.77,3.86)	0.21 (‐0.08,0.48)
SD ABA SC	SD RITUX IV	4.21 (0.44,42.54)	2.76 (0.56,19.85)	0.25 (‐0.16,0.61)
SD CERTO SC		3.74 (0.53,50.05)	2.65 (0.64,23.72)	0.23 (‐0.13,0.57)
SD ETN SC + MTX		5.89 (1.18,42.29)	3.44 (1.09,22.67)	0.34 (0.04,0.53)
SD INF IV + MTX		4.43 (0.91,31.70)	2.94 (0.95,18.79)	0.26 (‐0.02,0.47)
SD ABA IV + MTX		5.80 (1.18,40.44)	3.41 (1.10,21.64)	0.33 (0.04,0.55)
SD ADA SC + MTX		8.90 (1.82,65.79)	4.09 (1.35,26.12)	0.43 (0.14,0.66)
SD CERTO SC + MTX/CERTO+ MTX		8.30 (1.68,59.65)	4.00 (1.29,26.59)	0.42 (0.12,0.62)
SD RITUX IV + MTX		3.56 (0.84,23.14)	2.57 (0.90,15.84)	0.22 (‐0.04,0.42)
SD TOFA PO + MTX		9.40 (1.74,68.15)	4.19 (1.31,28.09)	0.44 (0.13,0.65)
SD GOLI SC + MTX		9.13 (1.73,70.86)	4.15 (1.30,28.21)	0.44 (0.13,0.66)
SD ABA SC + MTX		7.12 (1.31,53.91)	3.73 (1.18,24.59)	0.37 (0.06,0.62)
SD GOLI IV + MTX		3.47 (0.62,25.53)	2.49 (0.73,16.35)	0.21 (‐0.10,0.45)
SD ANA SC + MTX		4.30 (0.69,35.24)	2.88 (0.81,19.26)	0.26 (‐0.08,0.51)
SD TOCI IV + MTX		3.03 (0.48,24.29)	2.31 (0.60,15.65)	0.18 (‐0.15,0.46)
SD CERTO SC + DMARD		2.06 (0.34,19.39)	1.77 (0.45,13.85)	0.11 (‐0.22,0.35)
SD ADA SC + DMARD		1.26 (0.18,10.65)	1.21 (0.25,8.40)	0.03 (‐0.28,0.27)
SD ETN SC + DMARD		5.13 (0.82,40.39)	3.16 (0.90,22.15)	0.29 (‐0.04,0.58)
SD TOCI SC + DMARD		1.96 (0.28,17.69)	1.69 (0.38,11.57)	0.09 (‐0.22,0.40)
LD ADA SC		1.34 (0.23,11.47)	1.27 (0.33,9.14)	0.04 (‐0.28,0.22)
LD ETN SC		1.39 (0.26,10.49)	1.31 (0.38,8.58)	0.04 (‐0.26,0.21)
LD GOLI IV		1.55 (0.24,12.86)	1.43 (0.34,9.67)	0.06 (‐0.25,0.30)
LD TOCI IV		0.26 (0.03,2.85)	0.30 (0.04,2.65)	‐0.09 (‐0.40,0.05)
LD ADA SC + MTX		6.43 (1.26,49.13)	3.54 (1.14,24.27)	0.36 (0.05,0.61)
LD RITUX IV + MTX		3.16 (0.66,21.59)	2.40 (0.77,15.27)	0.19 (‐0.09,0.39)
LD ADA IV + MTX		5.98 (0.47,90.52)	3.31 (0.58,25.83)	0.33 (‐0.13,0.73)
LD ABA IV + MTX		3.14 (0.60,22.91)	2.37 (0.71,15.40)	0.19 (‐0.11,0.42)
LD ANA SC + MTX		2.97 (0.35,27.99)	2.24 (0.47,15.55)	0.17 (‐0.18,0.53)
LD CERTO SC + MTX		6.02 (0.94,48.13)	3.42 (0.97,23.32)	0.33 (‐0.01,0.61)
LD ETN SC + MTX		5.25 (0.87,42.64)	3.19 (0.92,22.59)	0.30 (‐0.03,0.56)
LD GOLI IV + MTX		3.07 (0.50,25.30)	2.31 (0.62,16.01)	0.18 (‐0.14,0.46)
LD TOCI IV + MTX		2.37 (0.42,19.76)	1.96 (0.53,13.70)	0.13 (‐0.17,0.41)
LD TOFA PO + MTX		5.16 (0.70,44.64)	3.14 (0.79,21.06)	0.29 (‐0.07,0.61)
HD TOCI IV		3.77 (0.81,28.69)	2.71 (0.88,17.89)	0.23 (‐0.05,0.42)
HD TOFA PO		4.12 (0.70,39.19)	2.85 (0.81,21.72)	0.25 (‐0.08,0.47)
HD ADA SC		1.90 (0.32,18.13)	1.67 (0.46,13.74)	0.09 (‐0.22,0.30)
HD ETN SC		2.85 (0.49,21.62)	2.25 (0.63,14.83)	0.17 (‐0.15,0.39)
HD GOLI SC		3.77 (0.70,28.57)	2.68 (0.81,18.53)	0.23 (‐0.08,0.45)
HD ABA SC		6.03 (0.63,63.43)	3.37 (0.73,24.85)	0.33 (‐0.10,0.67)
HD INF IV + MTX		7.28 (1.39,51.14)	3.77 (1.19,23.86)	0.39 (0.07,0.60)
HD TOCI IV + MTX		6.83 (1.35,52.63)	3.68 (1.17,25.31)	0.37 (0.07,0.58)
HD TOFA PO + MTX		7.46 (1.37,56.14)	3.85 (1.18,26.06)	0.39 (0.07,0.61)
HD GOLI SC + MTX		7.03 (1.24,55.18)	3.72 (1.12,25.45)	0.38 (0.05,0.62)
HD CERTO SC + MTX		10.00 (1.95,75.46)	4.32 (1.39,30.12)	0.46 (0.16,0.67)
HD ADA SC + MTX		8.21 (1.51,71.89)	3.95 (1.21,26.17)	0.41 (0.09,0.69)
HD TOCI IV + DMARD		1.42 (0.23,11.64)	1.33 (0.32,9.34)	0.05 (‐0.27,0.27)
SD ANA SC + SD ETN SC + MTX		3.78 (0.55,31.04)	2.64 (0.68,18.20)	0.22 (‐0.11,0.54)
SD ANA SC + LD ETN SC + MTX		5.70 (0.81,44.18)	3.32 (0.88,21.37)	0.32 (‐0.05,0.62)
SD CERTO SC	SD ABA SC	0.95 (0.15,6.00)	0.97 (0.34,3.23)	‐0.01 (‐0.43,0.39)
SD ETN SC + MTX		1.47 (0.27,6.88)	1.23 (0.55,3.54)	0.09 (‐0.31,0.42)
SD INF IV + MTX		1.12 (0.19,5.26)	1.07 (0.45,3.10)	0.03 (‐0.38,0.35)
SD ABA IV + MTX		1.44 (0.26,7.18)	1.22 (0.52,3.63)	0.09 (‐0.32,0.42)
SD ADA SC + MTX		2.31 (0.39,11.64)	1.50 (0.68,4.33)	0.20 (‐0.22,0.54)
SD CERTO SC + MTX/CERTO+ MTX		2.07 (0.36,10.29)	1.45 (0.64,4.08)	0.18 (‐0.24,0.51)
SD RITUX IV + MTX		0.90 (0.16,4.50)	0.94 (0.37,2.87)	‐0.02 (‐0.42,0.31)
SD TOFA PO + MTX		2.36 (0.39,12.22)	1.52 (0.68,4.38)	0.20 (‐0.21,0.54)
SD GOLI SC + MTX		2.32 (0.39,11.59)	1.49 (0.67,4.31)	0.20 (‐0.22,0.53)
SD ABA SC + MTX		1.80 (0.30,9.81)	1.35 (0.58,3.94)	0.14 (‐0.29,0.50)
SD GOLI IV + MTX		0.86 (0.14,4.71)	0.91 (0.33,2.85)	‐0.03 (‐0.44,0.32)
SD ANA SC + MTX		1.05 (0.16,6.47)	1.03 (0.37,3.30)	0.01 (‐0.42,0.39)
SD TOCI IV + MTX		0.75 (0.11,4.27)	0.83 (0.28,2.71)	‐0.06 (‐0.48,0.31)
SD CERTO SC + DMARD		0.52 (0.08,2.85)	0.64 (0.22,2.10)	‐0.14 (‐0.53,0.20)
SD ADA SC + DMARD		0.30 (0.04,2.06)	0.43 (0.09,1.69)	‐0.22 (‐0.59,0.14)
SD ETN SC + DMARD		1.27 (0.19,7.51)	1.14 (0.42,3.60)	0.06 (‐0.37,0.44)
SD TOCI SC + DMARD		0.49 (0.06,3.27)	0.62 (0.16,2.25)	‐0.14 (‐0.56,0.25)
LD ADA SC		0.34 (0.06,1.56)	0.46 (0.18,1.42)	‐0.21 (‐0.57,0.07)
LD ETN SC		0.35 (0.06,1.72)	0.48 (0.18,1.52)	‐0.20 (‐0.57,0.09)
LD GOLI IV		0.38 (0.05,2.21)	0.51 (0.14,1.80)	‐0.19 (‐0.59,0.15)
LD TOCI IV		0.06 (0.01,0.47)	0.10 (0.02,0.54)	‐0.35 (‐0.69,‐0.08)
LD ADA SC + MTX		1.60 (0.27,8.88)	1.29 (0.55,3.76)	0.11 (‐0.31,0.47)
LD RITUX IV + MTX		0.81 (0.14,4.00)	0.87 (0.33,2.63)	‐0.05 (‐0.44,0.28)
LD ADA IV + MTX		1.49 (0.12,14.01)	1.23 (0.26,4.12)	0.09 (‐0.45,0.56)
LD ABA IV + MTX		0.79 (0.12,4.23)	0.86 (0.30,2.68)	‐0.05 (‐0.46,0.31)
LD ANA SC + MTX		0.72 (0.09,6.25)	0.82 (0.19,3.03)	‐0.07 (‐0.52,0.40)
LD CERTO SC + MTX		1.44 (0.22,9.13)	1.21 (0.44,3.75)	0.09 (‐0.35,0.48)
LD ETN SC + MTX		1.30 (0.21,7.28)	1.15 (0.45,3.50)	0.06 (‐0.36,0.42)
LD GOLI IV + MTX		0.75 (0.11,4.54)	0.84 (0.28,2.79)	‐0.06 (‐0.47,0.32)
LD TOCI IV + MTX		0.60 (0.09,3.57)	0.72 (0.23,2.38)	‐0.11 (‐0.52,0.26)
LD TOFA PO + MTX		1.25 (0.16,9.65)	1.13 (0.34,3.72)	0.05 (‐0.42,0.48)
HD TOCI IV		0.96 (0.17,4.48)	0.98 (0.41,2.89)	‐0.01 (‐0.41,0.30)
HD TOFA PO		1.02 (0.20,4.82)	1.01 (0.45,2.95)	0.00 (‐0.37,0.32)
HD ADA SC		0.47 (0.09,2.27)	0.59 (0.24,1.83)	‐0.16 (‐0.53,0.15)
HD ETN SC		0.69 (0.12,3.76)	0.79 (0.30,2.55)	‐0.08 (‐0.46,0.27)
HD GOLI SC		0.96 (0.16,4.86)	0.97 (0.38,2.96)	‐0.01 (‐0.42,0.33)
HD ABA SC		1.41 (0.50,4.38)	1.19 (0.67,2.49)	0.08 (‐0.16,0.33)
HD INF IV + MTX		1.83 (0.31,9.05)	1.36 (0.59,3.92)	0.14 (‐0.28,0.48)
HD TOCI IV + MTX		1.75 (0.29,8.75)	1.34 (0.57,3.87)	0.13 (‐0.29,0.46)
HD TOFA PO + MTX		1.86 (0.31,9.51)	1.38 (0.60,3.99)	0.15 (‐0.28,0.49)
HD GOLI SC + MTX		1.78 (0.29,9.95)	1.35 (0.57,4.08)	0.14 (‐0.29,0.48)
HD CERTO SC + MTX		2.46 (0.44,13.05)	1.55 (0.72,4.43)	0.22 (‐0.19,0.55)
HD ADA SC + MTX		2.07 (0.31,11.93)	1.43 (0.57,4.07)	0.17 (‐0.27,0.54)
HD TOCI IV + DMARD		0.36 (0.05,2.15)	0.49 (0.13,1.73)	‐0.19 (‐0.59,0.15)
SD ANA SC + SD ETN SC + MTX		0.95 (0.14,5.66)	0.97 (0.32,2.91)	‐0.01 (‐0.43,0.38)
SD ANA SC + LD ETN SC + MTX		1.40 (0.21,8.53)	1.20 (0.43,3.59)	0.08 (‐0.36,0.47)
SD ETN SC + MTX	SD CERTO SC	1.55 (0.35,6.31)	1.28 (0.58,3.21)	0.10 (‐0.26,0.41)
SD INF IV + MTX		1.18 (0.23,4.70)	1.10 (0.45,2.78)	0.04 (‐0.35,0.33)
SD ABA IV + MTX		1.55 (0.28,6.56)	1.28 (0.53,3.25)	0.10 (‐0.30,0.41)
SD ADA SC + MTX		2.43 (0.44,10.13)	1.55 (0.69,3.86)	0.21 (‐0.20,0.51)
SD CERTO SC + MTX/CERTO+ MTX		2.25 (0.41,9.25)	1.51 (0.67,3.78)	0.19 (‐0.21,0.49)
SD RITUX IV + MTX		0.95 (0.19,3.97)	0.97 (0.39,2.56)	‐0.01 (‐0.38,0.29)
SD TOFA PO + MTX		2.46 (0.45,10.50)	1.56 (0.71,3.83)	0.22 (‐0.19,0.52)
SD GOLI SC + MTX		2.43 (0.47,10.61)	1.56 (0.72,3.91)	0.21 (‐0.18,0.51)
SD ABA SC + MTX		1.90 (0.35,8.57)	1.40 (0.59,3.58)	0.15 (‐0.25,0.47)
SD GOLI IV + MTX		0.91 (0.17,3.93)	0.94 (0.35,2.50)	‐0.02 (‐0.41,0.29)
SD ANA SC + MTX		1.13 (0.19,5.17)	1.07 (0.38,2.87)	0.03 (‐0.38,0.36)
SD TOCI IV + MTX		0.79 (0.14,4.01)	0.86 (0.29,2.49)	‐0.05 (‐0.44,0.31)
SD CERTO SC + DMARD		0.54 (0.11,2.40)	0.66 (0.24,1.83)	‐0.13 (‐0.48,0.18)
SD ADA SC + DMARD		0.33 (0.04,1.71)	0.45 (0.10,1.48)	‐0.20 (‐0.56,0.10)
SD ETN SC + DMARD		1.34 (0.22,6.51)	1.18 (0.45,3.07)	0.07 (‐0.34,0.41)
SD TOCI SC + DMARD		0.54 (0.07,2.78)	0.65 (0.17,1.93)	‐0.13 (‐0.52,0.21)
LD ADA SC		0.35 (0.08,1.39)	0.47 (0.20,1.29)	‐0.20 (‐0.52,0.06)
LD ETN SC		0.37 (0.08,1.51)	0.49 (0.18,1.36)	‐0.19 (‐0.52,0.07)
LD GOLI IV		0.40 (0.07,2.05)	0.54 (0.16,1.66)	‐0.18 (‐0.52,0.15)
LD TOCI IV		0.07 (0.01,0.43)	0.11 (0.02,0.51)	‐0.34 (‐0.64,‐0.10)
LD ADA SC + MTX		1.71 (0.30,7.31)	1.34 (0.56,3.27)	0.13 (‐0.28,0.44)
LD RITUX IV + MTX		0.85 (0.15,3.42)	0.90 (0.34,2.34)	‐0.04 (‐0.42,0.26)
LD ADA IV + MTX		1.55 (0.14,13.76)	1.26 (0.27,3.74)	0.10 (‐0.42,0.56)
LD ABA IV + MTX		0.83 (0.15,3.60)	0.89 (0.31,2.39)	‐0.04 (‐0.43,0.27)
LD ANA SC + MTX		0.79 (0.09,5.35)	0.86 (0.20,2.60)	‐0.05 (‐0.47,0.37)
LD CERTO SC + MTX		1.57 (0.25,7.88)	1.28 (0.47,3.40)	0.11 (‐0.32,0.46)
LD ETN SC + MTX		1.37 (0.24,6.67)	1.20 (0.45,3.19)	0.07 (‐0.33,0.42)
LD GOLI IV + MTX		0.79 (0.13,3.92)	0.87 (0.29,2.49)	‐0.05 (‐0.44,0.30)
LD TOCI IV + MTX		0.65 (0.11,3.09)	0.75 (0.24,2.14)	‐0.09 (‐0.47,0.24)
LD TOFA PO + MTX		1.38 (0.18,7.25)	1.19 (0.37,3.12)	0.07 (‐0.38,0.44)
HD TOCI IV		1.03 (0.22,3.76)	1.02 (0.45,2.52)	0.01 (‐0.36,0.27)
HD TOFA PO		1.06 (0.26,4.30)	1.04 (0.50,2.66)	0.01 (‐0.32,0.30)
HD ADA SC		0.49 (0.12,2.09)	0.62 (0.27,1.69)	‐0.15 (‐0.46,0.14)
HD ETN SC		0.75 (0.14,3.26)	0.83 (0.31,2.31)	‐0.06 (‐0.44,0.24)
HD GOLI SC		1.01 (0.20,4.04)	1.01 (0.41,2.60)	0.00 (‐0.37,0.30)
HD ABA SC		1.49 (0.25,9.40)	1.25 (0.44,3.33)	0.09 (‐0.31,0.50)
HD INF IV + MTX		1.89 (0.38,7.69)	1.40 (0.63,3.47)	0.15 (‐0.24,0.45)
HD TOCI IV + MTX		1.79 (0.38,7.48)	1.37 (0.63,3.45)	0.14 (‐0.23,0.44)
HD TOFA PO + MTX		1.95 (0.38,8.22)	1.42 (0.63,3.60)	0.16 (‐0.23,0.47)
HD GOLI SC + MTX		1.87 (0.33,8.17)	1.39 (0.58,3.65)	0.15 (‐0.26,0.46)
HD CERTO SC + MTX		2.68 (0.51,11.20)	1.61 (0.75,4.02)	0.24 (‐0.15,0.53)
HD ADA SC + MTX		2.17 (0.38,11.15)	1.48 (0.61,3.82)	0.18 (‐0.23,0.52)
HD TOCI IV + DMARD		0.38 (0.06,1.85)	0.51 (0.15,1.56)	‐0.18 (‐0.55,0.12)
SD ANA SC + SD ETN SC + MTX		1.01 (0.16,5.44)	1.01 (0.34,2.81)	0.00 (‐0.40,0.38)
SD ANA SC + LD ETN SC + MTX		1.49 (0.24,7.93)	1.25 (0.44,3.35)	0.09 (‐0.33,0.47)
SD INF IV + MTX	SD ETN SC + MTX	0.76 (0.43,1.28)	0.86 (0.60,1.14)	‐0.07 (‐0.20,0.06)
SD ABA IV + MTX		0.98 (0.54,1.79)	0.99 (0.71,1.33)	0.00 (‐0.15,0.14)
SD ADA SC + MTX		1.52 (0.78,3.23)	1.21 (0.88,1.65)	0.10 (‐0.06,0.27)
SD CERTO SC + MTX/CERTO+ MTX		1.39 (0.76,2.70)	1.16 (0.88,1.59)	0.08 (‐0.07,0.24)
SD RITUX IV + MTX		0.61 (0.31,1.21)	0.76 (0.49,1.11)	‐0.12 (‐0.27,0.05)
SD TOFA PO + MTX		1.57 (0.77,3.31)	1.22 (0.89,1.69)	0.11 (‐0.06,0.28)
SD GOLI SC + MTX		1.55 (0.70,3.44)	1.21 (0.83,1.73)	0.10 (‐0.09,0.28)
SD ABA SC + MTX		1.21 (0.53,2.65)	1.10 (0.70,1.54)	0.05 (‐0.15,0.23)
SD GOLI IV + MTX		0.57 (0.26,1.31)	0.73 (0.43,1.15)	‐0.13 (‐0.30,0.07)
SD ANA SC + MTX		0.72 (0.26,1.81)	0.84 (0.44,1.33)	‐0.08 (‐0.30,0.14)
SD TOCI IV + MTX		0.51 (0.18,1.39)	0.68 (0.32,1.19)	‐0.16 (‐0.38,0.08)
SD CERTO SC + DMARD		0.35 (0.11,1.14)	0.52 (0.22,1.08)	‐0.23 (‐0.47,0.03)
SD ADA SC + DMARD		0.21 (0.06,0.76)	0.34 (0.11,0.85)	‐0.31 (‐0.51,‐0.06)
SD ETN SC + DMARD		0.86 (0.33,2.27)	0.93 (0.50,1.47)	‐0.04 (‐0.26,0.20)
SD TOCI SC + DMARD		0.33 (0.10,1.24)	0.50 (0.18,1.12)	‐0.24 (‐0.45,0.05)
LD ADA SC		0.23 (0.08,0.64)	0.37 (0.18,0.74)	‐0.31 (‐0.50,‐0.10)
LD ETN SC		0.23 (0.12,0.48)	0.38 (0.23,0.63)	‐0.30 (‐0.45,‐0.15)
LD GOLI IV		0.26 (0.08,0.80)	0.41 (0.16,0.88)	‐0.28 (‐0.47,‐0.05)
LD TOCI IV		0.04 (0.01,0.17)	0.08 (0.02,0.28)	‐0.44 (‐0.60,‐0.28)
LD ADA SC + MTX		1.10 (0.50,2.53)	1.05 (0.68,1.51)	0.02 (‐0.16,0.22)
LD RITUX IV + MTX		0.54 (0.27,1.04)	0.70 (0.44,1.02)	‐0.14 (‐0.30,0.01)
LD ADA IV + MTX		0.98 (0.16,5.36)	0.99 (0.28,1.89)	0.00 (‐0.36,0.36)
LD ABA IV + MTX		0.52 (0.24,1.15)	0.69 (0.40,1.08)	‐0.15 (‐0.32,0.04)
LD ANA SC + MTX		0.49 (0.12,2.12)	0.66 (0.21,1.38)	‐0.16 (‐0.41,0.18)
LD CERTO SC + MTX		1.00 (0.36,2.80)	1.00 (0.53,1.57)	0.00 (‐0.23,0.24)
LD ETN SC + MTX		0.88 (0.40,1.93)	0.93 (0.57,1.33)	‐0.03 (‐0.22,0.15)
LD GOLI IV + MTX		0.52 (0.18,1.45)	0.68 (0.32,1.19)	‐0.15 (‐0.36,0.09)
LD TOCI IV + MTX		0.41 (0.14,1.14)	0.59 (0.25,1.08)	‐0.20 (‐0.42,0.03)
LD TOFA PO + MTX		0.85 (0.24,2.97)	0.92 (0.38,1.60)	‐0.04 (‐0.30,0.25)
HD TOCI IV		0.65 (0.36,1.23)	0.79 (0.56,1.12)	‐0.10 (‐0.25,0.05)
HD TOFA PO		0.70 (0.26,1.68)	0.82 (0.47,1.34)	‐0.09 (‐0.32,0.13)
HD ADA SC		0.32 (0.12,0.92)	0.48 (0.25,0.95)	‐0.25 (‐0.46,‐0.02)
HD ETN SC		0.48 (0.22,1.04)	0.65 (0.38,1.02)	‐0.17 (‐0.34,0.01)
HD GOLI SC		0.64 (0.28,1.48)	0.78 (0.47,1.24)	‐0.11 (‐0.29,0.09)
HD ABA SC		0.96 (0.21,5.15)	0.98 (0.37,2.00)	‐0.01 (‐0.35,0.37)
HD INF IV + MTX		1.23 (0.63,2.38)	1.10 (0.78,1.51)	0.05 (‐0.11,0.21)
HD TOCI IV + MTX		1.17 (0.59,2.28)	1.08 (0.76,1.49)	0.04 (‐0.13,0.20)
HD TOFA PO + MTX		1.26 (0.62,2.64)	1.11 (0.78,1.55)	0.06 (‐0.12,0.23)
HD GOLI SC + MTX		1.20 (0.54,2.74)	1.09 (0.71,1.57)	0.04 (‐0.15,0.23)
HD CERTO SC + MTX		1.69 (0.83,3.46)	1.25 (0.91,1.73)	0.12 (‐0.05,0.29)
HD ADA SC + MTX		1.39 (0.51,3.97)	1.16 (0.68,1.75)	0.08 (‐0.16,0.31)
HD TOCI IV + DMARD		0.24 (0.09,0.77)	0.39 (0.16,0.86)	‐0.29 (‐0.48,‐0.06)
SD ANA SC + SD ETN SC + MTX		0.63 (0.24,1.71)	0.78 (0.38,1.26)	‐0.11 (‐0.31,0.13)
SD ANA SC + LD ETN SC + MTX		0.95 (0.37,2.58)	0.97 (0.52,1.47)	‐0.01 (‐0.22,0.22)
SD ABA IV + MTX	SD INF IV + MTX	1.30 (0.75,2.23)	1.15 (0.85,1.58)	0.06 (‐0.07,0.19)
SD ADA SC + MTX		2.06 (1.02,4.14)	1.41 (1.01,2.07)	0.17 (0.00,0.33)
SD CERTO SC + MTX/CERTO+ MTX		1.85 (1.00,3.55)	1.35 (1.00,1.92)	0.15 (0.00,0.30)
SD RITUX IV + MTX		0.82 (0.42,1.59)	0.89 (0.58,1.31)	‐0.04 (‐0.20,0.11)
SD TOFA PO + MTX		2.08 (1.04,4.31)	1.42 (1.02,2.10)	0.18 (0.01,0.34)
SD GOLI SC + MTX		2.04 (0.93,4.39)	1.42 (0.96,2.10)	0.17 (‐0.02,0.35)
SD ABA SC + MTX		1.63 (0.72,3.47)	1.28 (0.83,1.89)	0.12 (‐0.08,0.29)
SD GOLI IV + MTX		0.77 (0.34,1.71)	0.86 (0.50,1.36)	‐0.06 (‐0.24,0.13)
SD ANA SC + MTX		0.96 (0.36,2.42)	0.97 (0.52,1.62)	‐0.01 (‐0.22,0.21)
SD TOCI IV + MTX		0.68 (0.23,1.82)	0.79 (0.37,1.41)	‐0.09 (‐0.30,0.15)
SD CERTO SC + DMARD		0.46 (0.14,1.58)	0.60 (0.26,1.34)	‐0.16 (‐0.40,0.10)
SD ADA SC + DMARD		0.28 (0.08,1.04)	0.40 (0.14,1.02)	‐0.24 (‐0.44,0.01)
SD ETN SC + DMARD		1.14 (0.39,3.45)	1.08 (0.56,1.87)	0.03 (‐0.21,0.29)
SD TOCI SC + DMARD		0.44 (0.12,1.72)	0.58 (0.20,1.34)	‐0.17 (‐0.40,0.13)
LD ADA SC		0.30 (0.11,0.91)	0.43 (0.21,0.94)	‐0.24 (‐0.44,‐0.02)
LD ETN SC		0.31 (0.15,0.68)	0.44 (0.25,0.76)	‐0.23 (‐0.39,‐0.08)
LD GOLI IV		0.35 (0.11,1.01)	0.48 (0.19,1.01)	‐0.21 (‐0.41,0.00)
LD TOCI IV		0.06 (0.01,0.23)	0.10 (0.02,0.33)	‐0.37 (‐0.56,‐0.21)
LD ADA SC + MTX		1.46 (0.70,3.34)	1.21 (0.81,1.83)	0.09 (‐0.09,0.28)
LD RITUX IV + MTX		0.71 (0.36,1.41)	0.82 (0.51,1.23)	‐0.08 (‐0.23,0.08)
LD ADA IV + MTX		1.30 (0.21,7.03)	1.15 (0.32,2.23)	0.06 (‐0.29,0.42)
LD ABA IV + MTX		0.70 (0.33,1.51)	0.81 (0.47,1.27)	‐0.08 (‐0.25,0.10)
LD ANA SC + MTX		0.65 (0.16,2.68)	0.77 (0.25,1.63)	‐0.09 (‐0.34,0.23)
LD CERTO SC + MTX		1.32 (0.49,3.72)	1.16 (0.64,1.91)	0.07 (‐0.16,0.31)
LD ETN SC + MTX		1.18 (0.48,2.76)	1.09 (0.64,1.72)	0.04 (‐0.17,0.24)
LD GOLI IV + MTX		0.68 (0.24,1.89)	0.80 (0.38,1.43)	‐0.08 (‐0.29,0.15)
LD TOCI IV + MTX		0.55 (0.18,1.51)	0.68 (0.30,1.28)	‐0.13 (‐0.35,0.10)
LD TOFA PO + MTX		1.14 (0.33,3.94)	1.07 (0.46,1.90)	0.03 (‐0.24,0.32)
HD TOCI IV		0.87 (0.46,1.66)	0.92 (0.65,1.38)	‐0.03 (‐0.19,0.12)
HD TOFA PO		0.94 (0.33,2.50)	0.96 (0.52,1.73)	‐0.02 (‐0.26,0.21)
HD ADA SC		0.43 (0.15,1.27)	0.56 (0.28,1.17)	‐0.18 (‐0.40,0.05)
HD ETN SC		0.65 (0.28,1.51)	0.76 (0.43,1.27)	‐0.10 (‐0.28,0.10)
HD GOLI SC		0.85 (0.38,2.01)	0.91 (0.54,1.52)	‐0.04 (‐0.23,0.17)
HD ABA SC		1.28 (0.27,7.19)	1.14 (0.44,2.59)	0.06 (‐0.29,0.45)
HD INF IV + MTX		1.63 (0.96,2.74)	1.28 (0.98,1.73)	0.12 (‐0.01,0.24)
HD TOCI IV + MTX		1.56 (0.79,3.03)	1.26 (0.88,1.85)	0.11 (‐0.05,0.26)
HD TOFA PO + MTX		1.67 (0.82,3.47)	1.29 (0.90,1.91)	0.12 (‐0.05,0.30)
HD GOLI SC + MTX		1.60 (0.73,3.62)	1.27 (0.84,1.94)	0.11 (‐0.08,0.31)
HD CERTO SC + MTX		2.24 (1.11,4.53)	1.46 (1.06,2.13)	0.19 (0.03,0.35)
HD ADA SC + MTX		1.85 (0.66,5.21)	1.35 (0.79,2.16)	0.15 (‐0.10,0.37)
HD TOCI IV + DMARD		0.32 (0.11,1.03)	0.45 (0.19,1.02)	‐0.22 (‐0.42,0.01)
SD ANA SC + SD ETN SC + MTX		0.84 (0.28,2.68)	0.91 (0.41,1.67)	‐0.04 (‐0.27,0.23)
SD ANA SC + LD ETN SC + MTX		1.28 (0.42,3.77)	1.14 (0.56,1.93)	0.06 (‐0.19,0.31)
SD ADA SC + MTX	SD ABA IV + MTX	1.57 (0.80,3.04)	1.22 (0.91,1.67)	0.11 (‐0.06,0.26)
SD CERTO SC + MTX/CERTO+ MTX		1.42 (0.77,2.72)	1.17 (0.88,1.65)	0.08 (‐0.06,0.24)
SD RITUX IV + MTX		0.63 (0.32,1.21)	0.77 (0.50,1.11)	‐0.11 (‐0.26,0.05)
SD TOFA PO + MTX		1.62 (0.79,3.31)	1.23 (0.89,1.78)	0.12 (‐0.06,0.28)
SD GOLI SC + MTX		1.58 (0.71,3.44)	1.22 (0.86,1.80)	0.11 (‐0.08,0.29)
SD ABA SC + MTX		1.25 (0.62,2.46)	1.11 (0.77,1.49)	0.05 (‐0.11,0.21)
SD GOLI IV + MTX		0.59 (0.27,1.35)	0.74 (0.43,1.17)	‐0.12 (‐0.30,0.07)
SD ANA SC + MTX		0.73 (0.28,1.97)	0.85 (0.45,1.40)	‐0.08 (‐0.29,0.16)
SD TOCI IV + MTX		0.52 (0.18,1.42)	0.68 (0.32,1.21)	‐0.15 (‐0.37,0.08)
SD CERTO SC + DMARD		0.36 (0.11,1.20)	0.52 (0.22,1.12)	‐0.22 (‐0.47,0.04)
SD ADA SC + DMARD		0.21 (0.06,0.81)	0.35 (0.12,0.88)	‐0.31 (‐0.52,‐0.05)
SD ETN SC + DMARD		0.88 (0.30,2.58)	0.93 (0.49,1.59)	‐0.03 (‐0.28,0.22)
SD TOCI SC + DMARD		0.34 (0.09,1.33)	0.51 (0.18,1.16)	‐0.24 (‐0.46,0.07)
LD ADA SC		0.23 (0.08,0.73)	0.38 (0.18,0.81)	‐0.30 (‐0.51,‐0.07)
LD ETN SC		0.24 (0.11,0.53)	0.39 (0.22,0.65)	‐0.30 (‐0.46,‐0.13)
LD GOLI IV		0.27 (0.09,0.77)	0.42 (0.16,0.86)	‐0.27 (‐0.47,‐0.06)
LD TOCI IV		0.05 (0.01,0.17)	0.09 (0.02,0.28)	‐0.44 (‐0.62,‐0.25)
LD ADA SC + MTX		1.13 (0.52,2.45)	1.06 (0.69,1.52)	0.03 (‐0.16,0.21)
LD RITUX IV + MTX		0.55 (0.27,1.09)	0.71 (0.45,1.05)	‐0.14 (‐0.30,0.02)
LD ADA IV + MTX		1.02 (0.16,5.57)	1.01 (0.27,1.87)	0.01 (‐0.36,0.36)
LD ABA IV + MTX		0.54 (0.28,1.03)	0.70 (0.44,1.01)	‐0.14 (‐0.28,0.01)
LD ANA SC + MTX		0.49 (0.12,2.19)	0.66 (0.21,1.45)	‐0.16 (‐0.40,0.19)
LD CERTO SC + MTX		1.01 (0.37,2.97)	1.01 (0.55,1.63)	0.00 (‐0.23,0.25)
LD ETN SC + MTX		0.92 (0.34,2.19)	0.95 (0.54,1.46)	‐0.02 (‐0.24,0.19)
LD GOLI IV + MTX		0.53 (0.19,1.50)	0.69 (0.33,1.22)	‐0.15 (‐0.36,0.09)
LD TOCI IV + MTX		0.41 (0.14,1.18)	0.59 (0.27,1.10)	‐0.20 (‐0.41,0.04)
LD TOFA PO + MTX		0.86 (0.25,3.13)	0.93 (0.40,1.64)	‐0.04 (‐0.29,0.26)
HD TOCI IV		0.67 (0.34,1.33)	0.80 (0.57,1.18)	‐0.10 (‐0.26,0.07)
HD TOFA PO		0.72 (0.25,1.95)	0.84 (0.46,1.49)	‐0.08 (‐0.32,0.16)
HD ADA SC		0.32 (0.12,0.96)	0.49 (0.25,0.97)	‐0.25 (‐0.46,‐0.01)
HD ETN SC		0.49 (0.22,1.16)	0.66 (0.38,1.08)	‐0.16 (‐0.34,0.03)
HD GOLI SC		0.65 (0.29,1.57)	0.78 (0.47,1.28)	‐0.10 (‐0.30,0.11)
HD ABA SC		0.98 (0.20,5.58)	0.99 (0.37,2.16)	‐0.01 (‐0.36,0.39)
HD INF IV + MTX		1.26 (0.64,2.52)	1.11 (0.80,1.58)	0.06 (‐0.11,0.22)
HD TOCI IV + MTX		1.20 (0.60,2.35)	1.09 (0.78,1.57)	0.04 (‐0.12,0.20)
HD TOFA PO + MTX		1.29 (0.63,2.67)	1.13 (0.79,1.61)	0.06 (‐0.11,0.23)
HD GOLI SC + MTX		1.23 (0.54,2.75)	1.10 (0.72,1.65)	0.05 (‐0.15,0.24)
HD CERTO SC + MTX		1.73 (0.85,3.54)	1.26 (0.93,1.85)	0.13 (‐0.04,0.30)
HD ADA SC + MTX		1.43 (0.51,3.93)	1.18 (0.69,1.77)	0.09 (‐0.16,0.31)
HD TOCI IV + DMARD		0.25 (0.08,0.80)	0.39 (0.16,0.88)	‐0.29 (‐0.49,‐0.05)
SD ANA SC + SD ETN SC + MTX		0.65 (0.20,2.08)	0.79 (0.36,1.45)	‐0.10 (‐0.34,0.18)
SD ANA SC + LD ETN SC + MTX		0.97 (0.31,3.09)	0.99 (0.49,1.63)	‐0.01 (‐0.26,0.26)
SD CERTO SC + MTX/CERTO+ MTX	SD ADA SC + MTX	0.91 (0.44,1.81)	0.96 (0.72,1.32)	‐0.02 (‐0.19,0.14)
SD RITUX IV + MTX		0.40 (0.19,0.83)	0.63 (0.41,0.91)	‐0.22 (‐0.39,‐0.05)
SD TOFA PO + MTX		1.03 (0.46,2.14)	1.01 (0.73,1.40)	0.01 (‐0.18,0.17)
SD GOLI SC + MTX		0.99 (0.43,2.34)	1.00 (0.71,1.43)	0.00 (‐0.19,0.20)
SD ABA SC + MTX		0.79 (0.39,1.57)	0.91 (0.63,1.20)	‐0.06 (‐0.22,0.10)
SD GOLI IV + MTX		0.38 (0.16,0.89)	0.61 (0.36,0.94)	‐0.23 (‐0.42,‐0.03)
SD ANA SC + MTX		0.47 (0.17,1.27)	0.70 (0.36,1.10)	‐0.18 (‐0.41,0.05)
SD TOCI IV + MTX		0.33 (0.11,1.02)	0.56 (0.26,1.01)	‐0.26 (‐0.49,0.00)
SD CERTO SC + DMARD		0.23 (0.06,0.84)	0.43 (0.19,0.91)	‐0.34 (‐0.59,‐0.04)
SD ADA SC + DMARD		0.13 (0.04,0.52)	0.29 (0.09,0.70)	‐0.42 (‐0.63,‐0.15)
SD ETN SC + DMARD		0.56 (0.19,1.62)	0.77 (0.41,1.24)	‐0.14 (‐0.38,0.11)
SD TOCI SC + DMARD		0.21 (0.05,0.85)	0.41 (0.15,0.92)	‐0.34 (‐0.58,‐0.04)
LD ADA SC		0.15 (0.05,0.48)	0.31 (0.15,0.62)	‐0.41 (‐0.62,‐0.16)
LD ETN SC		0.15 (0.06,0.36)	0.32 (0.18,0.54)	‐0.40 (‐0.58,‐0.22)
LD GOLI IV		0.17 (0.05,0.51)	0.34 (0.13,0.70)	‐0.38 (‐0.58,‐0.16)
LD TOCI IV		0.03 (0.00,0.13)	0.07 (0.01,0.24)	‐0.55 (‐0.73,‐0.34)
LD ADA SC + MTX		0.71 (0.38,1.36)	0.87 (0.62,1.14)	‐0.08 (‐0.22,0.07)
LD RITUX IV + MTX		0.35 (0.16,0.74)	0.58 (0.36,0.85)	‐0.25 (‐0.42,‐0.07)
LD ADA IV + MTX		0.65 (0.10,3.48)	0.82 (0.23,1.52)	‐0.10 (‐0.47,0.26)
LD ABA IV + MTX		0.34 (0.15,0.77)	0.58 (0.33,0.88)	‐0.25 (‐0.43,‐0.06)
LD ANA SC + MTX		0.32 (0.07,1.39)	0.54 (0.18,1.15)	‐0.26 (‐0.53,0.08)
LD CERTO SC + MTX		0.65 (0.22,1.91)	0.83 (0.44,1.29)	‐0.10 (‐0.35,0.14)
LD ETN SC + MTX		0.57 (0.21,1.54)	0.78 (0.44,1.20)	‐0.13 (‐0.36,0.10)
LD GOLI IV + MTX		0.34 (0.11,0.99)	0.56 (0.27,1.00)	‐0.26 (‐0.48,0.00)
LD TOCI IV + MTX		0.27 (0.08,0.78)	0.48 (0.22,0.88)	‐0.30 (‐0.53,‐0.06)
LD TOFA PO + MTX		0.56 (0.14,1.95)	0.77 (0.31,1.31)	‐0.14 (‐0.42,0.16)
HD TOCI IV		0.42 (0.20,0.90)	0.65 (0.46,0.94)	‐0.21 (‐0.37,‐0.03)
HD TOFA PO		0.45 (0.15,1.33)	0.68 (0.39,1.16)	‐0.19 (‐0.43,0.07)
HD ADA SC		0.21 (0.07,0.65)	0.40 (0.21,0.77)	‐0.36 (‐0.57,‐0.10)
HD ETN SC		0.32 (0.12,0.80)	0.54 (0.30,0.89)	‐0.27 (‐0.47,‐0.05)
HD GOLI SC		0.42 (0.16,1.06)	0.65 (0.38,1.04)	‐0.21 (‐0.42,0.01)
HD ABA SC		0.62 (0.12,3.54)	0.81 (0.32,1.66)	‐0.11 (‐0.47,0.28)
HD INF IV + MTX		0.80 (0.36,1.74)	0.91 (0.64,1.28)	‐0.05 (‐0.24,0.13)
HD TOCI IV + MTX		0.76 (0.36,1.61)	0.89 (0.63,1.25)	‐0.06 (‐0.24,0.11)
HD TOFA PO + MTX		0.83 (0.38,1.77)	0.92 (0.64,1.28)	‐0.04 (‐0.23,0.13)
HD GOLI SC + MTX		0.78 (0.33,1.82)	0.90 (0.60,1.31)	‐0.06 (‐0.25,0.14)
HD CERTO SC + MTX		1.11 (0.49,2.40)	1.04 (0.75,1.45)	0.02 (‐0.17,0.20)
HD ADA SC + MTX		0.92 (0.37,2.26)	0.96 (0.61,1.33)	‐0.02 (‐0.23,0.17)
HD TOCI IV + DMARD		0.16 (0.05,0.54)	0.32 (0.13,0.71)	‐0.39 (‐0.60,‐0.15)
SD ANA SC + SD ETN SC + MTX		0.42 (0.12,1.41)	0.65 (0.30,1.16)	‐0.21 (‐0.46,0.08)
SD ANA SC + LD ETN SC + MTX		0.62 (0.19,2.04)	0.81 (0.40,1.33)	‐0.11 (‐0.38,0.16)
SD RITUX IV + MTX	SD CERTO SC +	0.44 (0.21,0.90)	0.66 (0.42,0.94)	‐0.20 (‐0.36,‐0.03)
SD TOFA PO + MTX		1.12 (0.55,2.38)	1.05 (0.76,1.42)	0.03 (‐0.14,0.19)
SD GOLI SC + MTX		1.10 (0.50,2.45)	1.04 (0.74,1.45)	0.02 (‐0.16,0.20)
SD ABA SC + MTX		0.87 (0.37,1.95)	0.94 (0.60,1.33)	‐0.03 (‐0.24,0.15)
SD GOLI IV + MTX		0.42 (0.18,0.93)	0.63 (0.36,0.97)	‐0.21 (‐0.39,‐0.02)
SD ANA SC + MTX		0.51 (0.20,1.29)	0.72 (0.38,1.13)	‐0.16 (‐0.37,0.06)
SD TOCI IV + MTX		0.36 (0.12,1.04)	0.58 (0.27,1.02)	‐0.24 (‐0.46,0.01)
SD CERTO SC + DMARD		0.25 (0.07,0.83)	0.44 (0.19,0.90)	‐0.31 (‐0.55,‐0.05)
SD ADA SC + DMARD		0.15 (0.04,0.54)	0.29 (0.10,0.72)	‐0.39 (‐0.59,‐0.14)
SD ETN SC + DMARD		0.61 (0.21,1.83)	0.79 (0.42,1.29)	‐0.12 (‐0.37,0.14)
SD TOCI SC + DMARD		0.23 (0.07,0.87)	0.43 (0.15,0.93)	‐0.32 (‐0.55,‐0.03)
LD ADA SC		0.16 (0.06,0.51)	0.32 (0.16,0.65)	‐0.40 (‐0.59,‐0.15)
LD ETN SC		0.17 (0.08,0.37)	0.33 (0.19,0.55)	‐0.38 (‐0.54,‐0.21)
LD GOLI IV		0.19 (0.06,0.55)	0.35 (0.14,0.73)	‐0.36 (‐0.56,‐0.14)
LD TOCI IV		0.03 (0.01,0.13)	0.07 (0.01,0.24)	‐0.53 (‐0.69,‐0.33)
LD ADA SC + MTX		0.78 (0.37,1.77)	0.90 (0.59,1.28)	‐0.06 (‐0.24,0.13)
LD RITUX IV + MTX		0.39 (0.18,0.77)	0.60 (0.37,0.88)	‐0.23 (‐0.39,‐0.06)
LD ADA IV + MTX		0.69 (0.12,3.87)	0.85 (0.23,1.58)	‐0.09 (‐0.44,0.28)
LD ABA IV + MTX		0.37 (0.17,0.81)	0.59 (0.34,0.90)	‐0.23 (‐0.41,‐0.05)
LD ANA SC + MTX		0.35 (0.09,1.48)	0.56 (0.18,1.18)	‐0.24 (‐0.49,0.09)
LD CERTO SC + MTX		0.70 (0.29,1.84)	0.85 (0.49,1.27)	‐0.08 (‐0.28,0.14)
LD ETN SC + MTX		0.63 (0.24,1.55)	0.81 (0.46,1.21)	‐0.11 (‐0.33,0.10)
LD GOLI IV + MTX		0.37 (0.13,1.04)	0.58 (0.27,1.02)	‐0.23 (‐0.45,0.01)
LD TOCI IV + MTX		0.29 (0.10,0.83)	0.50 (0.22,0.91)	‐0.28 (‐0.50,‐0.04)
LD TOFA PO + MTX		0.60 (0.18,2.09)	0.79 (0.34,1.34)	‐0.12 (‐0.38,0.17)
HD TOCI IV		0.47 (0.24,0.90)	0.68 (0.48,0.94)	‐0.18 (‐0.34,‐0.03)
HD TOFA PO		0.50 (0.17,1.37)	0.71 (0.41,1.19)	‐0.17 (‐0.40,0.08)
HD ADA SC		0.22 (0.08,0.72)	0.41 (0.22,0.82)	‐0.34 (‐0.54,‐0.07)
HD ETN SC		0.34 (0.15,0.83)	0.56 (0.32,0.91)	‐0.25 (‐0.43,‐0.05)
HD GOLI SC		0.46 (0.19,1.06)	0.67 (0.41,1.03)	‐0.19 (‐0.38,0.01)
HD ABA SC		0.69 (0.14,4.04)	0.84 (0.33,1.75)	‐0.09 (‐0.45,0.31)
HD INF IV + MTX		0.88 (0.43,1.77)	0.94 (0.68,1.29)	‐0.03 (‐0.20,0.13)
HD TOCI IV + MTX		0.84 (0.41,1.64)	0.93 (0.67,1.25)	‐0.04 (‐0.21,0.12)
HD TOFA PO + MTX		0.89 (0.43,1.90)	0.95 (0.66,1.33)	‐0.03 (‐0.20,0.15)
HD GOLI SC + MTX		0.85 (0.38,1.96)	0.93 (0.62,1.32)	‐0.04 (‐0.23,0.16)
HD CERTO SC + MTX		1.20 (0.71,1.99)	1.07 (0.86,1.35)	0.04 (‐0.08,0.16)
HD ADA SC + MTX		1.00 (0.33,2.94)	1.00 (0.58,1.50)	0.00 (‐0.26,0.23)
HD TOCI IV + DMARD		0.17 (0.06,0.51)	0.34 (0.13,0.70)	‐0.37 (‐0.56,‐0.16)
SD ANA SC + SD ETN SC + MTX		0.46 (0.14,1.41)	0.67 (0.31,1.16)	‐0.19 (‐0.43,0.08)
SD ANA SC + LD ETN SC + MTX		0.68 (0.21,2.11)	0.84 (0.41,1.34)	‐0.09 (‐0.36,0.17)
SD TOFA PO + MTX	SD RITUX IV + MTX	2.55 (1.21,5.49)	1.60 (1.10,2.49)	0.22 (0.05,0.40)
SD GOLI SC + MTX		2.52 (1.10,5.87)	1.59 (1.05,2.58)	0.22 (0.02,0.41)
SD ABA SC + MTX		1.99 (0.85,4.70)	1.44 (0.91,2.34)	0.16 (‐0.04,0.36)
SD GOLI IV + MTX		0.93 (0.39,2.25)	0.96 (0.54,1.63)	‐0.01 (‐0.20,0.19)
SD ANA SC + MTX		1.18 (0.43,3.10)	1.10 (0.58,1.90)	0.04 (‐0.18,0.27)
SD TOCI IV + MTX		0.83 (0.27,2.38)	0.89 (0.41,1.67)	‐0.04 (‐0.27,0.20)
SD CERTO SC + DMARD		0.58 (0.17,1.88)	0.69 (0.28,1.51)	‐0.11 (‐0.36,0.14)
SD ADA SC + DMARD		0.34 (0.09,1.22)	0.46 (0.15,1.14)	‐0.19 (‐0.40,0.04)
SD ETN SC + DMARD		1.41 (0.45,4.13)	1.21 (0.61,2.20)	0.08 (‐0.18,0.33)
SD TOCI SC + DMARD		0.54 (0.14,2.01)	0.66 (0.23,1.53)	‐0.12 (‐0.36,0.16)
LD ADA SC		0.37 (0.13,1.14)	0.49 (0.23,1.10)	‐0.19 (‐0.41,0.03)
LD ETN SC		0.39 (0.17,0.86)	0.51 (0.27,0.90)	‐0.18 (‐0.36,‐0.02)
LD GOLI IV		0.42 (0.13,1.28)	0.55 (0.21,1.17)	‐0.16 (‐0.37,0.05)
LD TOCI IV		0.07 (0.01,0.29)	0.11 (0.02,0.39)	‐0.32 (‐0.52,‐0.16)
LD ADA SC + MTX		1.80 (0.79,4.27)	1.37 (0.86,2.21)	0.14 (‐0.06,0.34)
LD RITUX IV + MTX		0.88 (0.51,1.51)	0.92 (0.63,1.31)	‐0.03 (‐0.15,0.09)
LD ADA IV + MTX		1.62 (0.24,9.49)	1.30 (0.35,2.76)	0.11 (‐0.27,0.49)
LD ABA IV + MTX		0.85 (0.37,1.95)	0.90 (0.52,1.50)	‐0.04 (‐0.21,0.16)
LD ANA SC + MTX		0.80 (0.18,3.55)	0.87 (0.28,1.94)	‐0.05 (‐0.30,0.30)
LD CERTO SC + MTX		1.61 (0.57,4.78)	1.30 (0.70,2.29)	0.11 (‐0.12,0.36)
LD ETN SC + MTX		1.44 (0.56,3.77)	1.23 (0.70,2.10)	0.08 (‐0.13,0.31)
LD GOLI IV + MTX		0.84 (0.29,2.50)	0.89 (0.41,1.69)	‐0.04 (‐0.26,0.22)
LD TOCI IV + MTX		0.67 (0.22,1.89)	0.77 (0.33,1.52)	‐0.08 (‐0.30,0.15)
LD TOFA PO + MTX		1.39 (0.38,5.07)	1.20 (0.51,2.24)	0.08 (‐0.20,0.37)
HD TOCI IV		1.05 (0.53,2.18)	1.03 (0.69,1.66)	0.01 (‐0.15,0.17)
HD TOFA PO		1.13 (0.40,3.21)	1.07 (0.57,2.12)	0.03 (‐0.21,0.26)
HD ADA SC		0.53 (0.18,1.60)	0.64 (0.31,1.40)	‐0.13 (‐0.36,0.09)
HD ETN SC		0.79 (0.34,1.90)	0.86 (0.48,1.50)	‐0.05 (‐0.24,0.15)
HD GOLI SC		1.05 (0.42,2.59)	1.03 (0.59,1.82)	0.01 (‐0.20,0.21)
HD ABA SC		1.58 (0.32,8.91)	1.29 (0.47,3.02)	0.11 (‐0.25,0.49)
HD INF IV + MTX		2.00 (0.96,4.27)	1.45 (0.98,2.27)	0.16 (‐0.01,0.33)
HD TOCI IV + MTX		1.91 (0.92,3.98)	1.42 (0.96,2.24)	0.15 (‐0.02,0.32)
HD TOFA PO + MTX		2.08 (0.94,4.43)	1.47 (0.97,2.29)	0.17 (‐0.01,0.35)
HD GOLI SC + MTX		1.95 (0.83,4.69)	1.42 (0.90,2.35)	0.16 (‐0.04,0.36)
HD CERTO SC + MTX		2.74 (1.30,5.90)	1.64 (1.13,2.61)	0.24 (0.06,0.41)
HD ADA SC + MTX		2.29 (0.79,6.68)	1.52 (0.87,2.54)	0.20 (‐0.05,0.43)
HD TOCI IV + DMARD		0.39 (0.13,1.27)	0.51 (0.21,1.16)	‐0.18 (‐0.37,0.05)
SD ANA SC + SD ETN SC + MTX		1.03 (0.34,3.46)	1.02 (0.46,1.94)	0.01 (‐0.23,0.30)
SD ANA SC + LD ETN SC + MTX		1.55 (0.49,5.05)	1.27 (0.62,2.33)	0.10 (‐0.16,0.37)
SD GOLI SC + MTX	SD TOFA PO + MTX	0.97 (0.41,2.39)	0.99 (0.69,1.43)	‐0.01 (‐0.21,0.20)
SD ABA SC + MTX		0.78 (0.31,1.85)	0.90 (0.57,1.29)	‐0.06 (‐0.27,0.14)
SD GOLI IV + MTX		0.37 (0.14,0.93)	0.60 (0.34,0.96)	‐0.24 (‐0.44,‐0.02)
SD ANA SC + MTX		0.46 (0.16,1.29)	0.69 (0.35,1.12)	‐0.18 (‐0.42,0.06)
SD TOCI IV + MTX		0.32 (0.10,0.97)	0.55 (0.25,0.99)	‐0.27 (‐0.49,‐0.01)
SD CERTO SC + DMARD		0.22 (0.06,0.78)	0.42 (0.19,0.87)	‐0.34 (‐0.59,‐0.06)
SD ADA SC + DMARD		0.13 (0.03,0.53)	0.28 (0.09,0.70)	‐0.42 (‐0.63,‐0.15)
SD ETN SC + DMARD		0.55 (0.17,1.73)	0.76 (0.40,1.26)	‐0.14 (‐0.41,0.13)
SD TOCI SC + DMARD		0.21 (0.06,0.84)	0.41 (0.14,0.92)	‐0.35 (‐0.58,‐0.04)
LD ADA SC		0.14 (0.05,0.44)	0.30 (0.15,0.60)	‐0.42 (‐0.61,‐0.18)
LD ETN SC		0.15 (0.06,0.36)	0.31 (0.18,0.54)	‐0.41 (‐0.59,‐0.22)
LD GOLI IV		0.17 (0.05,0.53)	0.34 (0.13,0.73)	‐0.39 (‐0.60,‐0.15)
LD TOCI IV		0.03 (0.00,0.12)	0.07 (0.01,0.24)	‐0.55 (‐0.73,‐0.35)
LD ADA SC + MTX		0.70 (0.30,1.72)	0.86 (0.56,1.26)	‐0.08 (‐0.28,0.13)
LD RITUX IV + MTX		0.34 (0.16,0.74)	0.57 (0.35,0.86)	‐0.25 (‐0.42,‐0.07)
LD ADA IV + MTX		0.63 (0.10,3.41)	0.81 (0.22,1.47)	‐0.11 (‐0.47,0.25)
LD ABA IV + MTX		0.33 (0.14,0.79)	0.57 (0.33,0.90)	‐0.26 (‐0.44,‐0.06)
LD ANA SC + MTX		0.31 (0.07,1.42)	0.54 (0.17,1.16)	‐0.27 (‐0.53,0.08)
LD CERTO SC + MTX		0.63 (0.22,1.81)	0.82 (0.43,1.27)	‐0.11 (‐0.35,0.13)
LD ETN SC + MTX		0.56 (0.20,1.50)	0.77 (0.44,1.19)	‐0.14 (‐0.37,0.09)
LD GOLI IV + MTX		0.33 (0.10,1.07)	0.55 (0.26,1.03)	‐0.26 (‐0.49,0.02)
LD TOCI IV + MTX		0.26 (0.08,0.77)	0.48 (0.21,0.88)	‐0.31 (‐0.52,‐0.06)
LD TOFA PO + MTX		0.55 (0.17,1.67)	0.76 (0.34,1.20)	‐0.14 (‐0.39,0.11)
HD TOCI IV		0.41 (0.20,0.91)	0.65 (0.45,0.95)	‐0.21 (‐0.37,‐0.02)
HD TOFA PO		0.44 (0.15,1.23)	0.67 (0.39,1.12)	‐0.20 (‐0.43,0.05)
HD ADA SC		0.20 (0.07,0.63)	0.40 (0.21,0.76)	‐0.36 (‐0.57,‐0.10)
HD ETN SC		0.31 (0.12,0.76)	0.53 (0.30,0.87)	‐0.28 (‐0.47,‐0.06)
HD GOLI SC		0.41 (0.16,1.05)	0.64 (0.39,1.02)	‐0.21 (‐0.42,0.01)
HD ABA SC		0.61 (0.12,3.64)	0.81 (0.31,1.63)	‐0.12 (‐0.48,0.29)
HD INF IV + MTX		0.79 (0.36,1.73)	0.91 (0.63,1.26)	‐0.06 (‐0.24,0.13)
HD TOCI IV + MTX		0.74 (0.34,1.59)	0.88 (0.62,1.24)	‐0.07 (‐0.25,0.11)
HD TOFA PO + MTX		0.80 (0.48,1.30)	0.92 (0.72,1.12)	‐0.05 (‐0.17,0.06)
HD GOLI SC + MTX		0.76 (0.32,1.91)	0.90 (0.58,1.30)	‐0.06 (‐0.27,0.15)
HD CERTO SC + MTX		1.07 (0.50,2.42)	1.03 (0.75,1.45)	0.02 (‐0.16,0.20)
HD ADA SC + MTX		0.88 (0.32,2.70)	0.95 (0.55,1.43)	‐0.03 (‐0.27,0.22)
HD TOCI IV + DMARD		0.15 (0.05,0.52)	0.32 (0.13,0.71)	‐0.40 (‐0.60,‐0.15)
SD ANA SC + SD ETN SC + MTX		0.40 (0.12,1.45)	0.64 (0.28,1.17)	‐0.21 (‐0.48,0.09)
SD ANA SC + LD ETN SC + MTX		0.60 (0.18,2.12)	0.80 (0.38,1.33)	‐0.12 (‐0.39,0.17)
SD ABA SC + MTX	SD GOLI SC + MTX	0.79 (0.30,1.98)	0.91 (0.56,1.35)	‐0.06 (‐0.28,0.16)
SD GOLI IV + MTX		0.37 (0.14,0.96)	0.60 (0.34,0.98)	‐0.23 (‐0.44,‐0.01)
SD ANA SC + MTX		0.47 (0.16,1.31)	0.69 (0.36,1.12)	‐0.18 (‐0.42,0.06)
SD TOCI IV + MTX		0.33 (0.10,1.03)	0.56 (0.25,1.02)	‐0.26 (‐0.51,0.01)
SD CERTO SC + DMARD		0.23 (0.06,0.79)	0.43 (0.19,0.89)	‐0.33 (‐0.59,‐0.05)
SD ADA SC + DMARD		0.14 (0.03,0.53)	0.28 (0.09,0.71)	‐0.42 (‐0.64,‐0.14)
SD ETN SC + DMARD		0.56 (0.17,1.79)	0.77 (0.38,1.28)	‐0.14 (‐0.41,0.14)
SD TOCI SC + DMARD		0.21 (0.06,0.83)	0.41 (0.14,0.91)	‐0.34 (‐0.58,‐0.05)
LD ADA SC		0.15 (0.05,0.49)	0.30 (0.15,0.63)	‐0.41 (‐0.63,‐0.16)
LD ETN SC		0.15 (0.06,0.37)	0.32 (0.18,0.54)	‐0.40 (‐0.59,‐0.21)
LD GOLI IV		0.17 (0.05,0.55)	0.34 (0.13,0.73)	‐0.38 (‐0.59,‐0.14)
LD TOCI IV		0.03 (0.00,0.13)	0.07 (0.01,0.25)	‐0.55 (‐0.74,‐0.33)
LD ADA SC + MTX		0.73 (0.29,1.78)	0.87 (0.54,1.27)	‐0.08 (‐0.29,0.13)
LD RITUX IV + MTX		0.34 (0.15,0.82)	0.58 (0.35,0.91)	‐0.25 (‐0.43,‐0.05)
LD ADA IV + MTX		0.64 (0.10,3.52)	0.82 (0.22,1.51)	‐0.10 (‐0.48,0.26)
LD ABA IV + MTX		0.34 (0.14,0.86)	0.57 (0.32,0.93)	‐0.25 (‐0.44,‐0.04)
LD ANA SC + MTX		0.32 (0.07,1.48)	0.55 (0.17,1.17)	‐0.26 (‐0.55,0.09)
LD CERTO SC + MTX		0.65 (0.21,2.08)	0.83 (0.43,1.35)	‐0.10 (‐0.36,0.17)
LD ETN SC + MTX		0.57 (0.19,1.66)	0.78 (0.42,1.24)	‐0.13 (‐0.38,0.12)
LD GOLI IV + MTX		0.33 (0.11,1.06)	0.57 (0.25,1.03)	‐0.26 (‐0.49,0.01)
LD TOCI IV + MTX		0.27 (0.08,0.84)	0.48 (0.22,0.92)	‐0.30 (‐0.53,‐0.04)
LD TOFA PO + MTX		0.56 (0.14,2.01)	0.76 (0.31,1.35)	‐0.14 (‐0.43,0.16)
HD TOCI IV		0.43 (0.18,0.92)	0.66 (0.44,0.96)	‐0.20 (‐0.39,‐0.02)
HD TOFA PO		0.45 (0.15,1.37)	0.68 (0.39,1.18)	‐0.19 (‐0.43,0.08)
HD ADA SC		0.21 (0.06,0.69)	0.40 (0.21,0.80)	‐0.36 (‐0.59,‐0.08)
HD ETN SC		0.31 (0.12,0.81)	0.53 (0.30,0.90)	‐0.27 (‐0.48,‐0.05)
HD GOLI SC		0.42 (0.18,0.96)	0.65 (0.41,0.98)	‐0.21 (‐0.39,‐0.01)
HD ABA SC		0.63 (0.12,3.59)	0.81 (0.32,1.67)	‐0.11 (‐0.47,0.28)
HD INF IV + MTX		0.80 (0.34,1.90)	0.91 (0.62,1.34)	‐0.05 (‐0.25,0.15)
HD TOCI IV + MTX		0.76 (0.32,1.72)	0.89 (0.62,1.30)	‐0.07 (‐0.26,0.13)
HD TOFA PO + MTX		0.82 (0.34,1.98)	0.92 (0.62,1.35)	‐0.05 (‐0.25,0.16)
HD GOLI SC + MTX		0.78 (0.42,1.45)	0.90 (0.66,1.16)	‐0.06 (‐0.20,0.09)
HD CERTO SC + MTX		1.11 (0.45,2.57)	1.04 (0.74,1.48)	0.02 (‐0.18,0.22)
HD ADA SC + MTX		0.91 (0.28,2.80)	0.96 (0.53,1.48)	‐0.02 (‐0.30,0.23)
HD TOCI IV + DMARD		0.16 (0.05,0.53)	0.32 (0.13,0.70)	‐0.39 (‐0.61,‐0.15)
SD ANA SC + SD ETN SC + MTX		0.41 (0.12,1.56)	0.65 (0.28,1.23)	‐0.21 (‐0.48,0.10)
SD ANA SC + LD ETN SC + MTX		0.62 (0.17,2.19)	0.81 (0.38,1.38)	‐0.11 (‐0.41,0.18)
SD GOLI IV + MTX	SD ABA SC + MTX	0.47 (0.18,1.28)	0.67 (0.38,1.13)	‐0.18 (‐0.39,0.06)
SD ANA SC + MTX		0.58 (0.20,1.86)	0.76 (0.39,1.39)	‐0.13 (‐0.37,0.15)
SD TOCI IV + MTX		0.41 (0.13,1.36)	0.61 (0.28,1.18)	‐0.21 (‐0.45,0.07)
SD CERTO SC + DMARD		0.29 (0.08,1.13)	0.48 (0.20,1.07)	‐0.28 (‐0.55,0.03)
SD ADA SC + DMARD		0.17 (0.04,0.76)	0.32 (0.10,0.84)	‐0.36 (‐0.59,‐0.06)
SD ETN SC + DMARD		0.71 (0.21,2.38)	0.84 (0.43,1.51)	‐0.08 (‐0.37,0.21)
SD TOCI SC + DMARD		0.28 (0.07,1.15)	0.47 (0.16,1.08)	‐0.28 (‐0.54,0.03)
LD ADA SC		0.19 (0.06,0.64)	0.34 (0.17,0.75)	‐0.35 (‐0.58,‐0.09)
LD ETN SC		0.19 (0.07,0.49)	0.35 (0.19,0.63)	‐0.35 (‐0.55,‐0.14)
LD GOLI IV		0.21 (0.06,0.70)	0.38 (0.15,0.82)	‐0.33 (‐0.56,‐0.08)
LD TOCI IV		0.04 (0.01,0.17)	0.08 (0.01,0.27)	‐0.49 (‐0.69,‐0.26)
LD ADA SC + MTX		0.91 (0.39,2.24)	0.96 (0.63,1.44)	‐0.02 (‐0.22,0.19)
LD RITUX IV + MTX		0.44 (0.19,1.08)	0.64 (0.38,1.04)	‐0.19 (‐0.39,0.02)
LD ADA IV + MTX		0.82 (0.13,4.51)	0.92 (0.25,1.83)	‐0.05 (‐0.42,0.33)
LD ABA IV + MTX		0.43 (0.18,1.07)	0.63 (0.36,1.04)	‐0.20 (‐0.40,0.02)
LD ANA SC + MTX		0.40 (0.09,1.99)	0.60 (0.19,1.37)	‐0.21 (‐0.49,0.16)
LD CERTO SC + MTX		0.81 (0.27,2.63)	0.91 (0.48,1.61)	‐0.05 (‐0.30,0.23)
LD ETN SC + MTX		0.72 (0.25,2.12)	0.86 (0.47,1.45)	‐0.08 (‐0.32,0.18)
LD GOLI IV + MTX		0.42 (0.14,1.37)	0.62 (0.29,1.18)	‐0.20 (‐0.44,0.08)
LD TOCI IV + MTX		0.33 (0.10,1.12)	0.53 (0.24,1.06)	‐0.25 (‐0.49,0.03)
LD TOFA PO + MTX		0.70 (0.18,2.71)	0.84 (0.34,1.58)	‐0.09 (‐0.38,0.23)
HD TOCI IV		0.54 (0.23,1.29)	0.72 (0.48,1.16)	‐0.15 (‐0.35,0.06)
HD TOFA PO		0.58 (0.19,1.81)	0.75 (0.42,1.40)	‐0.13 (‐0.39,0.14)
HD ADA SC		0.26 (0.08,0.88)	0.44 (0.23,0.92)	‐0.30 (‐0.53,‐0.03)
HD ETN SC		0.39 (0.15,1.05)	0.60 (0.33,1.03)	‐0.22 (‐0.43,0.01)
HD GOLI SC		0.54 (0.19,1.44)	0.72 (0.41,1.23)	‐0.15 (‐0.39,0.08)
HD ABA SC		0.80 (0.15,4.83)	0.90 (0.34,2.00)	‐0.05 (‐0.43,0.35)
HD INF IV + MTX		1.01 (0.42,2.46)	1.01 (0.68,1.58)	0.00 (‐0.20,0.21)
HD TOCI IV + MTX		0.96 (0.41,2.31)	0.98 (0.67,1.56)	‐0.01 (‐0.21,0.20)
HD TOFA PO + MTX		1.02 (0.42,2.59)	1.01 (0.68,1.61)	0.01 (‐0.20,0.23)
HD GOLI SC + MTX		0.98 (0.38,2.69)	0.99 (0.64,1.61)	0.00 (‐0.23,0.23)
HD CERTO SC + MTX		1.37 (0.59,3.51)	1.14 (0.81,1.83)	0.07 (‐0.12,0.29)
HD ADA SC + MTX		1.15 (0.40,3.40)	1.07 (0.63,1.69)	0.03 (‐0.22,0.27)
HD TOCI IV + DMARD		0.20 (0.06,0.73)	0.36 (0.14,0.83)	‐0.34 (‐0.57,‐0.07)
SD ANA SC + SD ETN SC + MTX		0.52 (0.15,1.89)	0.71 (0.32,1.35)	‐0.15 (‐0.42,0.15)
SD ANA SC + LD ETN SC + MTX		0.78 (0.24,2.91)	0.89 (0.44,1.60)	‐0.06 (‐0.32,0.25)
SD ANA SC + MTX	SD GOLI IV + MTX	1.25 (0.43,3.50)	1.14 (0.58,2.11)	0.05 (‐0.19,0.29)
SD TOCI IV + MTX		0.88 (0.28,2.81)	0.92 (0.41,1.93)	‐0.03 (‐0.28,0.24)
SD CERTO SC + DMARD		0.60 (0.17,2.29)	0.71 (0.29,1.72)	‐0.10 (‐0.36,0.19)
SD ADA SC + DMARD		0.36 (0.09,1.41)	0.48 (0.15,1.26)	‐0.18 (‐0.43,0.07)
SD ETN SC + DMARD		1.48 (0.46,4.78)	1.26 (0.63,2.44)	0.09 (‐0.17,0.36)
SD TOCI SC + DMARD		0.58 (0.14,2.34)	0.68 (0.23,1.72)	‐0.11 (‐0.36,0.20)
LD ADA SC		0.39 (0.12,1.34)	0.51 (0.22,1.23)	‐0.18 (‐0.42,0.06)
LD ETN SC		0.41 (0.16,1.00)	0.52 (0.27,1.00)	‐0.17 (‐0.38,0.00)
LD GOLI IV		0.45 (0.17,1.17)	0.57 (0.24,1.11)	‐0.15 (‐0.34,0.03)
LD TOCI IV		0.08 (0.01,0.34)	0.12 (0.02,0.42)	‐0.31 (‐0.53,‐0.13)
LD ADA SC + MTX		1.90 (0.74,5.11)	1.43 (0.85,2.58)	0.15 (‐0.07,0.37)
LD RITUX IV + MTX		0.94 (0.39,2.24)	0.96 (0.55,1.70)	‐0.01 (‐0.22,0.17)
LD ADA IV + MTX		1.76 (0.23,10.18)	1.36 (0.35,3.06)	0.13 (‐0.27,0.50)
LD ABA IV + MTX		0.92 (0.35,2.27)	0.95 (0.52,1.66)	‐0.02 (‐0.23,0.18)
LD ANA SC + MTX		0.84 (0.19,4.05)	0.90 (0.30,2.20)	‐0.04 (‐0.31,0.32)
LD CERTO SC + MTX		1.73 (0.55,5.37)	1.35 (0.69,2.63)	0.13 (‐0.14,0.38)
LD ETN SC + MTX		1.52 (0.52,4.45)	1.27 (0.68,2.43)	0.10 (‐0.15,0.34)
LD GOLI IV + MTX		0.89 (0.36,2.24)	0.93 (0.49,1.66)	‐0.02 (‐0.22,0.19)
LD TOCI IV + MTX		0.72 (0.21,2.28)	0.80 (0.34,1.75)	‐0.07 (‐0.33,0.18)
LD TOFA PO + MTX		1.50 (0.37,5.83)	1.26 (0.51,2.57)	0.09 (‐0.21,0.40)
HD TOCI IV		1.13 (0.47,2.63)	1.08 (0.66,1.95)	0.03 (‐0.18,0.21)
HD TOFA PO		1.22 (0.38,3.66)	1.13 (0.56,2.37)	0.05 (‐0.23,0.28)
HD ADA SC		0.55 (0.18,1.87)	0.66 (0.31,1.57)	‐0.12 (‐0.36,0.12)
HD ETN SC		0.84 (0.31,2.23)	0.89 (0.46,1.71)	‐0.04 (‐0.26,0.18)
HD GOLI SC		1.12 (0.42,2.87)	1.07 (0.59,1.99)	0.02 (‐0.20,0.23)
HD ABA SC		1.69 (0.31,10.13)	1.34 (0.46,3.48)	0.12 (‐0.26,0.51)
HD INF IV + MTX		2.13 (0.87,5.23)	1.51 (0.92,2.69)	0.18 (‐0.03,0.37)
HD TOCI IV + MTX		2.05 (0.82,4.82)	1.48 (0.91,2.61)	0.17 (‐0.05,0.36)
HD TOFA PO + MTX		2.19 (0.87,5.57)	1.53 (0.93,2.69)	0.18 (‐0.03,0.39)
HD GOLI SC + MTX		2.07 (0.80,5.42)	1.48 (0.89,2.70)	0.17 (‐0.05,0.39)
HD CERTO SC + MTX		2.92 (1.21,7.21)	1.70 (1.08,3.06)	0.25 (0.05,0.45)
HD ADA SC + MTX		2.44 (0.73,7.73)	1.59 (0.85,3.00)	0.21 (‐0.07,0.46)
HD TOCI IV + DMARD		0.41 (0.12,1.43)	0.53 (0.21,1.28)	‐0.16 (‐0.41,0.07)
SD ANA SC + SD ETN SC + MTX		1.10 (0.30,3.93)	1.06 (0.45,2.20)	0.02 (‐0.25,0.31)
SD ANA SC + LD ETN SC + MTX		1.66 (0.45,5.64)	1.33 (0.61,2.64)	0.12 (‐0.17,0.40)
SD TOCI IV + MTX	SD ANA SC + MTX	0.70 (0.20,2.50)	0.80 (0.36,1.77)	‐0.08 (‐0.35,0.20)
SD CERTO SC + DMARD		0.50 (0.12,1.96)	0.63 (0.24,1.59)	‐0.15 (‐0.44,0.14)
SD ADA SC + DMARD		0.29 (0.07,1.32)	0.42 (0.13,1.20)	‐0.23 (‐0.49,0.06)
SD ETN SC + DMARD		1.19 (0.34,4.17)	1.10 (0.54,2.30)	0.04 (‐0.25,0.33)
SD TOCI SC + DMARD		0.46 (0.11,1.92)	0.60 (0.20,1.48)	‐0.16 (‐0.44,0.14)
LD ADA SC		0.31 (0.09,1.15)	0.44 (0.20,1.11)	‐0.23 (‐0.49,0.02)
LD ETN SC		0.33 (0.11,0.96)	0.46 (0.23,0.96)	‐0.22 (‐0.46,‐0.01)
LD GOLI IV		0.36 (0.10,1.24)	0.50 (0.19,1.16)	‐0.20 (‐0.45,0.04)
LD TOCI IV		0.06 (0.01,0.30)	0.10 (0.02,0.38)	‐0.36 (‐0.60,‐0.14)
LD ADA SC + MTX		1.53 (0.54,4.58)	1.25 (0.73,2.43)	0.10 (‐0.15,0.35)
LD RITUX IV + MTX		0.74 (0.28,2.00)	0.83 (0.47,1.62)	‐0.07 (‐0.29,0.15)
LD ADA IV + MTX		1.40 (0.18,9.16)	1.19 (0.30,2.80)	0.08 (‐0.33,0.48)
LD ABA IV + MTX		0.73 (0.24,2.19)	0.83 (0.41,1.67)	‐0.07 (‐0.32,0.17)
LD ANA SC + MTX		0.68 (0.18,2.54)	0.80 (0.29,1.65)	‐0.08 (‐0.33,0.22)
LD CERTO SC + MTX		1.38 (0.42,4.91)	1.19 (0.60,2.37)	0.08 (‐0.21,0.36)
LD ETN SC + MTX		1.23 (0.38,4.08)	1.12 (0.59,2.30)	0.05 (‐0.22,0.32)
LD GOLI IV + MTX		0.71 (0.22,2.47)	0.82 (0.37,1.72)	‐0.08 (‐0.34,0.21)
LD TOCI IV + MTX		0.57 (0.16,2.01)	0.70 (0.30,1.59)	‐0.12 (‐0.39,0.16)
LD TOFA PO + MTX		1.18 (0.26,4.90)	1.10 (0.42,2.37)	0.04 (‐0.29,0.36)
HD TOCI IV		0.90 (0.35,2.35)	0.94 (0.57,1.81)	‐0.02 (‐0.25,0.19)
HD TOFA PO		0.98 (0.29,3.14)	0.99 (0.50,2.13)	‐0.01 (‐0.29,0.25)
HD ADA SC		0.44 (0.13,1.65)	0.58 (0.27,1.45)	‐0.17 (‐0.44,0.10)
HD ETN SC		0.66 (0.22,2.12)	0.77 (0.40,1.62)	‐0.09 (‐0.34,0.16)
HD GOLI SC		0.89 (0.31,2.72)	0.94 (0.51,1.90)	‐0.03 (‐0.27,0.22)
HD ABA SC		1.34 (0.24,8.97)	1.17 (0.41,3.20)	0.07 (‐0.33,0.49)
HD INF IV + MTX		1.69 (0.62,4.76)	1.31 (0.80,2.53)	0.13 (‐0.11,0.36)
HD TOCI IV + MTX		1.61 (0.61,4.65)	1.28 (0.79,2.51)	0.11 (‐0.12,0.35)
HD TOFA PO + MTX		1.73 (0.63,5.21)	1.32 (0.79,2.67)	0.13 (‐0.11,0.38)
HD GOLI SC + MTX		1.65 (0.58,5.18)	1.28 (0.76,2.51)	0.12 (‐0.13,0.37)
HD CERTO SC + MTX		2.34 (0.90,6.51)	1.49 (0.96,2.81)	0.20 (‐0.02,0.42)
HD ADA SC + MTX		1.94 (0.57,7.07)	1.37 (0.74,2.82)	0.16 (‐0.13,0.44)
HD TOCI IV + DMARD		0.34 (0.10,1.28)	0.47 (0.18,1.18)	‐0.21 (‐0.47,0.05)
SD ANA SC + SD ETN SC + MTX		0.89 (0.25,3.60)	0.93 (0.40,2.08)	‐0.03 (‐0.32,0.30)
SD ANA SC + LD ETN SC + MTX		1.31 (0.35,5.32)	1.16 (0.53,2.44)	0.06 (‐0.24,0.38)
SD CERTO SC + DMARD	SD TOCI IV + MTX	0.69 (0.17,2.87)	0.77 (0.30,2.15)	‐0.07 (‐0.36,0.20)
SD ADA SC + DMARD		0.40 (0.09,1.87)	0.51 (0.15,1.58)	‐0.16 (‐0.42,0.12)
SD ETN SC + DMARD		1.72 (0.44,6.77)	1.38 (0.61,3.23)	0.12 (‐0.19,0.42)
SD TOCI SC + DMARD		0.65 (0.15,2.82)	0.74 (0.25,2.02)	‐0.08 (‐0.36,0.22)
LD ADA SC		0.45 (0.13,1.65)	0.56 (0.24,1.49)	‐0.14 (‐0.41,0.08)
LD ETN SC		0.46 (0.16,1.50)	0.57 (0.27,1.37)	‐0.14 (‐0.38,0.07)
LD GOLI IV		0.51 (0.13,2.07)	0.62 (0.21,1.70)	‐0.12 (‐0.39,0.14)
LD TOCI IV		0.09 (0.01,0.40)	0.13 (0.02,0.46)	‐0.28 (‐0.51,‐0.10)
LD ADA SC + MTX		2.17 (0.70,7.11)	1.55 (0.83,3.37)	0.18 (‐0.08,0.43)
LD RITUX IV + MTX		1.06 (0.37,3.23)	1.04 (0.53,2.28)	0.01 (‐0.22,0.24)
LD ADA IV + MTX		1.98 (0.23,13.19)	1.46 (0.34,3.71)	0.16 (‐0.26,0.54)
LD ABA IV + MTX		1.03 (0.33,3.27)	1.02 (0.48,2.30)	0.01 (‐0.25,0.25)
LD ANA SC + MTX		0.95 (0.19,5.03)	0.97 (0.29,2.74)	‐0.01 (‐0.31,0.36)
LD CERTO SC + MTX		1.96 (0.52,7.60)	1.47 (0.68,3.41)	0.15 (‐0.15,0.45)
LD ETN SC + MTX		1.74 (0.48,6.39)	1.39 (0.65,3.29)	0.13 (‐0.17,0.40)
LD GOLI IV + MTX		1.02 (0.25,3.92)	1.01 (0.39,2.49)	0.00 (‐0.29,0.29)
LD TOCI IV + MTX		0.81 (0.26,2.44)	0.86 (0.39,1.85)	‐0.04 (‐0.28,0.18)
LD TOFA PO + MTX		1.69 (0.34,7.74)	1.36 (0.50,3.23)	0.12 (‐0.23,0.45)
HD TOCI IV		1.29 (0.51,3.31)	1.17 (0.69,2.40)	0.06 (‐0.16,0.24)
HD TOFA PO		1.38 (0.37,4.61)	1.22 (0.56,2.95)	0.07 (‐0.23,0.32)
HD ADA SC		0.64 (0.18,2.34)	0.73 (0.33,1.88)	‐0.09 (‐0.36,0.15)
HD ETN SC		0.94 (0.29,3.21)	0.96 (0.46,2.27)	‐0.01 (‐0.27,0.24)
HD GOLI SC		1.26 (0.39,4.32)	1.16 (0.57,2.76)	0.05 (‐0.22,0.31)
HD ABA SC		1.90 (0.35,11.83)	1.45 (0.51,4.05)	0.14 (‐0.23,0.54)
HD INF IV + MTX		2.42 (0.81,7.42)	1.63 (0.90,3.53)	0.21 (‐0.05,0.44)
HD TOCI IV + MTX		2.33 (0.88,6.34)	1.61 (0.94,3.39)	0.20 (‐0.03,0.40)
HD TOFA PO + MTX		2.51 (0.77,8.00)	1.65 (0.88,3.62)	0.21 (‐0.06,0.45)
HD GOLI SC + MTX		2.34 (0.71,8.13)	1.60 (0.83,3.76)	0.20 (‐0.08,0.46)
HD CERTO SC + MTX		3.34 (1.08,10.66)	1.87 (1.03,4.06)	0.28 (0.02,0.51)
HD ADA SC + MTX		2.76 (0.73,10.83)	1.71 (0.84,3.87)	0.24 (‐0.07,0.52)
HD TOCI IV + DMARD		0.48 (0.13,1.88)	0.58 (0.22,1.57)	‐0.13 (‐0.39,0.12)
SD ANA SC + SD ETN SC + MTX		1.27 (0.32,5.18)	1.16 (0.47,2.80)	0.05 (‐0.25,0.36)
SD ANA SC + LD ETN SC + MTX		1.89 (0.47,7.69)	1.44 (0.63,3.35)	0.14 (‐0.17,0.45)
SD ADA SC + DMARD	SD CERTO SC + DMARD	0.60 (0.16,2.21)	0.67 (0.22,1.78)	‐0.08 (‐0.30,0.15)
SD ETN SC + DMARD		2.43 (0.66,9.99)	1.75 (0.76,4.25)	0.19 (‐0.09,0.50)
SD TOCI SC + DMARD		0.96 (0.24,3.63)	0.97 (0.33,2.46)	‐0.01 (‐0.25,0.27)
LD ADA SC		0.65 (0.18,2.32)	0.72 (0.28,1.93)	‐0.07 (‐0.32,0.13)
LD ETN SC		0.68 (0.21,2.24)	0.74 (0.32,1.86)	‐0.06 (‐0.30,0.13)
LD GOLI IV		0.75 (0.16,3.15)	0.80 (0.24,2.39)	‐0.05 (‐0.32,0.22)
LD TOCI IV		0.12 (0.02,0.64)	0.16 (0.03,0.68)	‐0.20 (‐0.43,‐0.05)
LD ADA SC + MTX		3.14 (0.82,12.22)	2.02 (0.89,4.88)	0.25 (‐0.05,0.52)
LD RITUX IV + MTX		1.52 (0.46,5.28)	1.34 (0.59,3.28)	0.08 (‐0.17,0.33)
LD ADA IV + MTX		2.77 (0.33,19.55)	1.85 (0.43,5.19)	0.22 (‐0.17,0.62)
LD ABA IV + MTX		1.50 (0.41,5.47)	1.32 (0.54,3.32)	0.08 (‐0.18,0.35)
LD ANA SC + MTX		1.39 (0.25,7.96)	1.26 (0.35,3.73)	0.06 (‐0.24,0.44)
LD CERTO SC + MTX		2.84 (0.67,12.21)	1.90 (0.77,4.65)	0.23 (‐0.08,0.54)
LD ETN SC + MTX		2.54 (0.64,9.87)	1.80 (0.76,4.44)	0.20 (‐0.09,0.49)
LD GOLI IV + MTX		1.50 (0.35,6.23)	1.32 (0.46,3.53)	0.08 (‐0.21,0.38)
LD TOCI IV + MTX		1.15 (0.30,4.82)	1.10 (0.41,3.01)	0.03 (‐0.23,0.31)
LD TOFA PO + MTX		2.41 (0.44,12.35)	1.76 (0.56,4.60)	0.19 (‐0.16,0.53)
HD TOCI IV		1.87 (0.64,5.60)	1.53 (0.75,3.52)	0.13 (‐0.10,0.33)
HD TOFA PO		1.98 (0.59,6.42)	1.58 (0.72,3.76)	0.15 (‐0.12,0.37)
HD ADA SC		0.92 (0.26,3.13)	0.94 (0.38,2.46)	‐0.01 (‐0.26,0.20)
HD ETN SC		1.36 (0.40,4.99)	1.25 (0.53,3.13)	0.06 (‐0.19,0.32)
HD GOLI SC		1.83 (0.50,6.69)	1.51 (0.65,3.81)	0.13 (‐0.15,0.38)
HD ABA SC		2.77 (0.51,16.05)	1.90 (0.64,5.14)	0.22 (‐0.14,0.58)
HD INF IV + MTX		3.49 (1.03,12.10)	2.11 (1.02,4.80)	0.28 (0.01,0.53)
HD TOCI IV + MTX		3.33 (1.03,11.15)	2.08 (1.02,4.74)	0.27 (0.01,0.50)
HD TOFA PO + MTX		3.59 (1.01,12.56)	2.14 (1.01,4.94)	0.29 (0.00,0.54)
HD GOLI SC + MTX		3.41 (1.00,13.70)	2.08 (1.00,5.04)	0.27 (0.00,0.55)
HD CERTO SC + MTX		4.76 (1.39,17.80)	2.42 (1.20,5.58)	0.35 (0.08,0.60)
HD ADA SC + MTX		3.98 (0.87,18.35)	2.22 (0.92,5.31)	0.31 (‐0.03,0.61)
HD TOCI IV + DMARD		0.69 (0.22,2.34)	0.75 (0.30,1.91)	‐0.06 (‐0.27,0.16)
SD ANA SC + SD ETN SC + MTX		1.83 (0.40,8.62)	1.50 (0.52,4.00)	0.13 (‐0.19,0.45)
SD ANA SC + LD ETN SC + MTX		2.73 (0.58,12.40)	1.86 (0.70,4.57)	0.22 (‐0.11,0.54)
SD ETN SC + DMARD	SD ADA SC + DMARD	4.19 (1.03,16.78)	2.67 (1.02,7.96)	0.27 (0.01,0.53)
SD TOCI SC + DMARD		1.61 (0.45,5.68)	1.44 (0.53,3.88)	0.07 (‐0.13,0.31)
LD ADA SC		1.10 (0.25,5.16)	1.08 (0.34,4.15)	0.01 (‐0.25,0.19)
LD ETN SC		1.12 (0.30,4.34)	1.10 (0.40,3.61)	0.02 (‐0.22,0.19)
LD GOLI IV		1.26 (0.25,6.03)	1.21 (0.34,4.43)	0.03 (‐0.23,0.28)
LD TOCI IV		0.21 (0.03,1.31)	0.25 (0.04,1.28)	‐0.12 (‐0.36,0.02)
LD ADA SC + MTX		5.32 (1.22,21.84)	3.02 (1.15,9.46)	0.34 (0.04,0.57)
LD RITUX IV + MTX		2.61 (0.71,9.79)	2.03 (0.79,6.26)	0.17 (‐0.07,0.37)
LD ADA IV + MTX		4.64 (0.55,36.88)	2.76 (0.64,9.90)	0.30 (‐0.09,0.69)
LD ABA IV + MTX		2.57 (0.61,9.99)	2.01 (0.71,6.28)	0.16 (‐0.10,0.39)
LD ANA SC + MTX		2.33 (0.39,15.09)	1.86 (0.49,6.95)	0.15 (‐0.15,0.52)
LD CERTO SC + MTX		4.80 (1.03,20.93)	2.84 (1.02,8.79)	0.31 (0.00,0.58)
LD ETN SC + MTX		4.24 (0.92,18.33)	2.70 (0.95,8.61)	0.28 (‐0.02,0.54)
LD GOLI IV + MTX		2.50 (0.53,11.38)	1.98 (0.63,6.55)	0.15 (‐0.11,0.44)
LD TOCI IV + MTX		1.96 (0.44,8.68)	1.69 (0.55,5.53)	0.11 (‐0.15,0.37)
LD TOFA PO + MTX		4.02 (0.75,22.03)	2.58 (0.82,8.69)	0.27 (‐0.05,0.59)
HD TOCI IV		3.12 (0.93,10.30)	2.29 (0.95,6.72)	0.21 (‐0.02,0.37)
HD TOFA PO		3.34 (0.77,14.33)	2.38 (0.84,8.27)	0.23 (‐0.06,0.44)
HD ADA SC		1.53 (0.37,7.20)	1.41 (0.48,5.23)	0.07 (‐0.20,0.27)
HD ETN SC		2.29 (0.55,9.79)	1.86 (0.67,5.97)	0.14 (‐0.12,0.38)
HD GOLI SC		3.15 (0.75,12.83)	2.30 (0.82,7.36)	0.21 (‐0.06,0.44)
HD ABA SC		4.68 (0.73,35.39)	2.80 (0.79,11.14)	0.30 (‐0.07,0.66)
HD INF IV + MTX		5.90 (1.53,22.18)	3.21 (1.28,9.75)	0.36 (0.10,0.58)
HD TOCI IV + MTX		5.62 (1.49,20.38)	3.15 (1.26,9.32)	0.35 (0.09,0.55)
HD TOFA PO + MTX		6.10 (1.44,22.51)	3.25 (1.25,9.98)	0.37 (0.09,0.59)
HD GOLI SC + MTX		5.85 (1.36,23.34)	3.15 (1.20,10.00)	0.36 (0.07,0.59)
HD CERTO SC + MTX		8.25 (2.16,30.92)	3.66 (1.48,11.08)	0.44 (0.17,0.65)
HD ADA SC + MTX		6.84 (1.41,32.79)	3.36 (1.23,10.84)	0.39 (0.07,0.67)
HD TOCI IV + DMARD		1.17 (0.38,3.50)	1.14 (0.47,2.90)	0.02 (‐0.16,0.19)
SD ANA SC + SD ETN SC + MTX		3.13 (0.63,15.56)	2.26 (0.72,7.46)	0.20 (‐0.09,0.50)
SD ANA SC + LD ETN SC + MTX		4.64 (0.94,21.72)	2.83 (0.96,8.93)	0.30 (‐0.01,0.59)
SD TOCI SC + DMARD	SD ETN SC + DMARD	0.39 (0.09,1.50)	0.55 (0.19,1.27)	‐0.20 (‐0.48,0.09)
LD ADA SC		0.26 (0.07,1.01)	0.40 (0.18,1.01)	‐0.27 (‐0.54,0.00)
LD ETN SC		0.27 (0.09,0.82)	0.42 (0.21,0.87)	‐0.26 (‐0.51,‐0.04)
LD GOLI IV		0.30 (0.07,1.17)	0.45 (0.16,1.11)	‐0.24 (‐0.51,0.04)
LD TOCI IV		0.05 (0.01,0.26)	0.09 (0.02,0.36)	‐0.40 (‐0.66,‐0.17)
LD ADA SC + MTX		1.29 (0.41,4.09)	1.13 (0.64,2.23)	0.06 (‐0.21,0.33)
LD RITUX IV + MTX		0.62 (0.21,1.88)	0.76 (0.40,1.50)	‐0.11 (‐0.37,0.14)
LD ADA IV + MTX		1.16 (0.15,7.23)	1.08 (0.28,2.45)	0.03 (‐0.38,0.44)
LD ABA IV + MTX		0.61 (0.18,1.97)	0.75 (0.36,1.54)	‐0.11 (‐0.39,0.16)
LD ANA SC + MTX		0.56 (0.10,3.09)	0.71 (0.21,1.89)	‐0.13 (‐0.45,0.27)
LD CERTO SC + MTX		1.17 (0.29,4.63)	1.08 (0.51,2.27)	0.04 (‐0.29,0.35)
LD ETN SC + MTX		1.03 (0.29,3.59)	1.02 (0.51,2.04)	0.01 (‐0.29,0.30)
LD GOLI IV + MTX		0.61 (0.16,2.30)	0.74 (0.31,1.61)	‐0.11 (‐0.41,0.18)
LD TOCI IV + MTX		0.48 (0.12,1.70)	0.64 (0.25,1.41)	‐0.16 (‐0.45,0.12)
LD TOFA PO + MTX		1.00 (0.19,4.51)	1.00 (0.37,2.17)	0.00 (‐0.36,0.35)
HD TOCI IV		0.77 (0.27,2.14)	0.86 (0.51,1.63)	‐0.06 (‐0.31,0.17)
HD TOFA PO		0.82 (0.22,2.74)	0.89 (0.46,1.91)	‐0.05 (‐0.35,0.23)
HD ADA SC		0.37 (0.10,1.42)	0.52 (0.25,1.27)	‐0.21 (‐0.49,0.07)
HD ETN SC		0.56 (0.18,1.70)	0.71 (0.36,1.41)	‐0.13 (‐0.39,0.11)
HD GOLI SC		0.75 (0.23,2.38)	0.85 (0.45,1.72)	‐0.07 (‐0.34,0.19)
HD ABA SC		1.14 (0.20,7.19)	1.07 (0.40,2.73)	0.03 (‐0.37,0.44)
HD INF IV + MTX		1.43 (0.45,4.68)	1.19 (0.70,2.32)	0.09 (‐0.19,0.36)
HD TOCI IV + MTX		1.35 (0.48,4.16)	1.16 (0.71,2.26)	0.07 (‐0.17,0.33)
HD TOFA PO + MTX		1.46 (0.46,4.62)	1.21 (0.70,2.29)	0.09 (‐0.19,0.35)
HD GOLI SC + MTX		1.38 (0.43,4.58)	1.17 (0.67,2.32)	0.08 (‐0.20,0.36)
HD CERTO SC + MTX		1.98 (0.65,5.90)	1.36 (0.84,2.66)	0.16 (‐0.10,0.41)
HD ADA SC + MTX		1.63 (0.45,6.67)	1.25 (0.65,2.55)	0.12 (‐0.19,0.43)
HD TOCI IV + DMARD		0.28 (0.08,1.02)	0.43 (0.17,1.02)	‐0.25 (‐0.51,0.01)
SD ANA SC + SD ETN SC + MTX		0.73 (0.18,3.07)	0.84 (0.35,1.87)	‐0.07 (‐0.38,0.26)
SD ANA SC + LD ETN SC + MTX		1.10 (0.27,4.41)	1.05 (0.47,2.23)	0.02 (‐0.30,0.34)
LD ADA SC	SD TOCI SC + DMARD	0.69 (0.15,2.89)	0.75 (0.26,2.49)	‐0.06 (‐0.37,0.15)
LD ETN SC		0.72 (0.18,2.77)	0.77 (0.30,2.35)	‐0.05 (‐0.34,0.14)
LD GOLI IV		0.77 (0.15,3.70)	0.82 (0.24,2.77)	‐0.04 (‐0.35,0.22)
LD TOCI IV		0.13 (0.02,0.74)	0.17 (0.03,0.76)	‐0.19 (‐0.49,‐0.03)
LD ADA SC + MTX		3.34 (0.82,13.39)	2.09 (0.89,6.26)	0.26 (‐0.05,0.52)
LD RITUX IV + MTX		1.60 (0.43,6.16)	1.39 (0.59,4.04)	0.09 (‐0.19,0.32)
LD ADA IV + MTX		2.88 (0.34,24.83)	1.91 (0.45,6.86)	0.23 (‐0.19,0.65)
LD ABA IV + MTX		1.59 (0.38,6.12)	1.39 (0.54,3.95)	0.09 (‐0.22,0.34)
LD ANA SC + MTX		1.47 (0.28,8.57)	1.30 (0.38,4.59)	0.07 (‐0.25,0.44)
LD CERTO SC + MTX		3.02 (0.67,13.54)	1.98 (0.78,5.72)	0.23 (‐0.09,0.53)
LD ETN SC + MTX		2.65 (0.56,11.24)	1.85 (0.71,5.70)	0.21 (‐0.13,0.48)
LD GOLI IV + MTX		1.53 (0.32,7.64)	1.35 (0.46,4.40)	0.08 (‐0.24,0.40)
LD TOCI IV + MTX		1.23 (0.28,5.39)	1.16 (0.42,3.63)	0.04 (‐0.25,0.31)
LD TOFA PO + MTX		2.59 (0.47,14.40)	1.82 (0.61,5.73)	0.20 (‐0.16,0.54)
HD TOCI IV		1.97 (0.59,6.57)	1.59 (0.73,4.24)	0.14 (‐0.13,0.33)
HD TOFA PO		2.09 (0.50,8.90)	1.64 (0.67,5.08)	0.16 (‐0.16,0.39)
HD ADA SC		0.98 (0.22,4.20)	0.98 (0.36,3.28)	0.00 (‐0.32,0.22)
HD ETN SC		1.47 (0.36,6.01)	1.31 (0.52,3.96)	0.07 (‐0.22,0.32)
HD GOLI SC		1.94 (0.48,7.88)	1.57 (0.64,4.74)	0.13 (‐0.17,0.38)
HD ABA SC		2.90 (0.46,23.04)	1.94 (0.61,7.28)	0.23 (‐0.17,0.62)
HD INF IV + MTX		3.70 (0.92,14.22)	2.19 (0.95,6.30)	0.29 (‐0.02,0.52)
HD TOCI IV + MTX		3.55 (0.95,12.45)	2.18 (0.97,6.02)	0.28 (‐0.01,0.50)
HD TOFA PO + MTX		3.81 (0.95,14.85)	2.24 (0.97,6.42)	0.29 (‐0.01,0.54)
HD GOLI SC + MTX		3.63 (0.90,14.77)	2.18 (0.94,6.34)	0.28 (‐0.03,0.54)
HD CERTO SC + MTX		5.07 (1.33,19.89)	2.51 (1.15,7.28)	0.36 (0.07,0.60)
HD ADA SC + MTX		4.25 (0.84,20.80)	2.32 (0.91,6.75)	0.31 (‐0.04,0.62)
HD TOCI IV + DMARD		0.72 (0.24,2.22)	0.78 (0.35,1.87)	‐0.05 (‐0.26,0.13)
SD ANA SC + SD ETN SC + MTX		1.97 (0.38,9.73)	1.57 (0.52,4.79)	0.13 (‐0.20,0.45)
SD ANA SC + LD ETN SC + MTX		3.01 (0.56,12.97)	1.96 (0.69,5.90)	0.23 (‐0.13,0.52)
LD ETN SC	LD ADA SC	1.04 (0.35,2.94)	1.03 (0.42,2.40)	0.01 (‐0.16,0.16)
LD GOLI IV		1.15 (0.29,4.45)	1.12 (0.34,3.09)	0.02 (‐0.18,0.27)
LD TOCI IV		0.19 (0.03,0.90)	0.23 (0.04,0.91)	‐0.13 (‐0.28,‐0.01)
LD ADA SC + MTX		4.87 (1.49,15.92)	2.83 (1.31,5.92)	0.33 (0.08,0.56)
LD RITUX IV + MTX		2.36 (0.80,6.85)	1.89 (0.85,4.11)	0.16 (‐0.04,0.37)
LD ADA IV + MTX		4.39 (0.62,26.94)	2.69 (0.67,6.30)	0.30 (‐0.07,0.66)
LD ABA IV + MTX		2.31 (0.66,7.47)	1.86 (0.74,4.26)	0.15 (‐0.07,0.39)
LD ANA SC + MTX		2.16 (0.39,11.29)	1.77 (0.46,4.90)	0.14 (‐0.13,0.51)
LD CERTO SC + MTX		4.38 (1.11,17.68)	2.71 (1.08,5.91)	0.30 (0.02,0.59)
LD ETN SC + MTX		3.89 (1.08,13.39)	2.52 (1.06,5.44)	0.27 (0.02,0.54)
LD GOLI IV + MTX		2.28 (0.59,8.60)	1.83 (0.66,4.47)	0.15 (‐0.09,0.44)
LD TOCI IV + MTX		1.81 (0.49,5.91)	1.57 (0.57,3.64)	0.10 (‐0.11,0.35)
LD TOFA PO + MTX		3.79 (0.74,15.77)	2.50 (0.79,5.64)	0.27 (‐0.05,0.57)
HD TOCI IV		2.90 (1.06,7.27)	2.15 (1.05,4.29)	0.21 (0.01,0.38)
HD TOFA PO		3.08 (1.11,8.05)	2.22 (1.08,4.53)	0.22 (0.02,0.40)
HD ADA SC		1.41 (0.67,2.96)	1.31 (0.73,2.36)	0.05 (‐0.07,0.19)
HD ETN SC		2.12 (0.63,6.81)	1.76 (0.69,4.07)	0.13 (‐0.08,0.37)
HD GOLI SC		2.88 (0.90,8.57)	2.12 (0.92,4.70)	0.20 (‐0.02,0.42)
HD ABA SC		4.27 (0.90,22.60)	2.65 (0.93,6.40)	0.30 (‐0.02,0.63)
HD INF IV + MTX		5.40 (1.69,16.10)	2.99 (1.40,6.04)	0.36 (0.11,0.57)
HD TOCI IV + MTX		5.22 (1.74,14.19)	2.94 (1.43,5.80)	0.35 (0.12,0.54)
HD TOFA PO + MTX		5.51 (1.82,16.31)	2.99 (1.48,6.04)	0.36 (0.13,0.57)
HD GOLI SC + MTX		5.32 (1.53,16.94)	2.96 (1.34,6.13)	0.35 (0.09,0.58)
HD CERTO SC + MTX		7.41 (2.25,23.01)	3.40 (1.66,6.78)	0.44 (0.18,0.64)
HD ADA SC + MTX		6.10 (1.57,24.34)	3.11 (1.37,6.65)	0.39 (0.09,0.65)
HD TOCI IV + DMARD		1.07 (0.28,3.93)	1.05 (0.34,2.76)	0.01 (‐0.16,0.24)
SD ANA SC + SD ETN SC + MTX		2.81 (0.67,11.10)	2.09 (0.73,4.98)	0.20 (‐0.07,0.50)
SD ANA SC + LD ETN SC + MTX		4.24 (0.97,16.58)	2.64 (0.98,5.85)	0.30 (‐0.01,0.58)
LD GOLI IV	LD ETN SC	1.11 (0.33,3.54)	1.09 (0.39,2.59)	0.02 (‐0.15,0.24)
LD TOCI IV		0.18 (0.03,0.79)	0.22 (0.04,0.81)	‐0.14 (‐0.28,‐0.02)
LD ADA SC + MTX		4.67 (1.86,12.20)	2.73 (1.50,5.07)	0.32 (0.13,0.54)
LD RITUX IV + MTX		2.26 (0.97,5.21)	1.82 (0.98,3.37)	0.15 (0.00,0.34)
LD ADA IV + MTX		4.10 (0.66,25.89)	2.54 (0.71,5.84)	0.30 (‐0.06,0.66)
LD ABA IV + MTX		2.21 (0.89,5.52)	1.80 (0.92,3.38)	0.14 (‐0.02,0.35)
LD ANA SC + MTX		2.08 (0.48,9.29)	1.72 (0.54,4.08)	0.13 (‐0.10,0.47)
LD CERTO SC + MTX		4.18 (1.39,13.73)	2.59 (1.27,5.14)	0.30 (0.06,0.55)
LD ETN SC + MTX		3.74 (1.36,10.23)	2.44 (1.24,4.59)	0.27 (0.06,0.49)
LD GOLI IV + MTX		2.14 (0.71,6.86)	1.76 (0.76,3.82)	0.14 (‐0.06,0.40)
LD TOCI IV + MTX		1.75 (0.54,5.07)	1.53 (0.61,3.27)	0.10 (‐0.10,0.33)
LD TOFA PO + MTX		3.63 (0.92,13.79)	2.37 (0.93,5.09)	0.26 (‐0.01,0.55)
HD TOCI IV		2.75 (1.33,5.89)	2.06 (1.22,3.69)	0.20 (0.06,0.35)
HD TOFA PO		2.95 (1.04,7.65)	2.15 (1.03,4.40)	0.21 (0.01,0.40)
HD ADA SC		1.35 (0.49,4.07)	1.27 (0.57,3.00)	0.05 (‐0.12,0.24)
HD ETN SC		2.03 (0.82,4.99)	1.69 (0.85,3.23)	0.13 (‐0.03,0.32)
HD GOLI SC		2.72 (1.08,7.03)	2.06 (1.06,3.99)	0.19 (0.01,0.39)
HD ABA SC		4.14 (0.85,22.78)	2.53 (0.88,6.31)	0.30 (‐0.03,0.63)
HD INF IV + MTX		5.17 (2.25,12.14)	2.87 (1.68,5.13)	0.35 (0.17,0.53)
HD TOCI IV + MTX		4.98 (2.21,11.49)	2.83 (1.64,5.15)	0.34 (0.17,0.51)
HD TOFA PO + MTX		5.30 (2.31,12.72)	2.91 (1.67,5.28)	0.35 (0.17,0.54)
HD GOLI SC + MTX		5.08 (2.05,12.85)	2.85 (1.59,5.23)	0.34 (0.15,0.54)
HD CERTO SC + MTX		7.09 (3.03,16.65)	3.29 (1.95,5.89)	0.43 (0.23,0.59)
HD ADA SC + MTX		5.98 (1.81,19.47)	3.02 (1.51,5.84)	0.38 (0.11,0.62)
HD TOCI IV + DMARD		1.02 (0.32,3.40)	1.02 (0.39,2.53)	0.00 (‐0.16,0.23)
SD ANA SC + SD ETN SC + MTX		2.69 (0.82,9.62)	2.02 (0.86,4.34)	0.19 (‐0.03,0.48)
SD ANA SC + LD ETN SC + MTX		4.01 (1.27,13.05)	2.54 (1.19,5.03)	0.29 (0.04,0.55)
LD TOCI IV	LD GOLI IV	0.17 (0.03,0.91)	0.20 (0.04,0.92)	‐0.15 (‐0.39,‐0.01)
LD ADA SC + MTX		4.25 (1.31,14.65)	2.52 (1.19,6.45)	0.30 (0.06,0.53)
LD RITUX IV + MTX		2.07 (0.67,6.74)	1.70 (0.77,4.45)	0.13 (‐0.09,0.34)
LD ADA IV + MTX		3.84 (0.48,26.26)	2.35 (0.55,7.55)	0.27 (‐0.12,0.66)
LD ABA IV + MTX		2.02 (0.62,7.01)	1.67 (0.72,4.41)	0.13 (‐0.10,0.35)
LD ANA SC + MTX		1.89 (0.36,10.40)	1.59 (0.45,5.05)	0.11 (‐0.17,0.48)
LD CERTO SC + MTX		3.84 (1.04,16.07)	2.38 (1.03,6.81)	0.28 (0.01,0.56)
LD ETN SC + MTX		3.42 (0.94,12.61)	2.26 (0.96,6.13)	0.25 (‐0.01,0.50)
LD GOLI IV + MTX		1.99 (0.74,5.68)	1.63 (0.81,3.78)	0.12 (‐0.06,0.35)
LD TOCI IV + MTX		1.61 (0.39,6.55)	1.42 (0.50,4.14)	0.08 (‐0.18,0.33)
LD TOFA PO + MTX		3.29 (0.72,15.29)	2.19 (0.80,6.39)	0.24 (‐0.06,0.55)
HD TOCI IV		2.51 (0.84,7.85)	1.93 (0.91,5.00)	0.18 (‐0.04,0.36)
HD TOFA PO		2.67 (0.72,9.88)	1.99 (0.81,5.75)	0.20 (‐0.08,0.41)
HD ADA SC		1.24 (0.32,5.01)	1.17 (0.44,3.65)	0.03 (‐0.22,0.25)
HD ETN SC		1.83 (0.54,6.74)	1.57 (0.65,4.33)	0.11 (‐0.13,0.34)
HD GOLI SC		2.47 (0.75,8.14)	1.90 (0.83,5.01)	0.17 (‐0.06,0.39)
HD ABA SC		3.74 (0.60,27.98)	2.34 (0.71,8.23)	0.27 (‐0.10,0.65)
HD INF IV + MTX		4.69 (1.60,15.36)	2.65 (1.30,6.97)	0.33 (0.11,0.53)
HD TOCI IV + MTX		4.56 (1.52,13.83)	2.62 (1.27,6.60)	0.32 (0.09,0.51)
HD TOFA PO + MTX		4.81 (1.46,16.33)	2.67 (1.23,7.00)	0.33 (0.09,0.56)
HD GOLI SC + MTX		4.62 (1.46,15.62)	2.64 (1.23,6.90)	0.32 (0.08,0.55)
HD CERTO SC + MTX		6.52 (2.12,21.71)	3.02 (1.47,8.12)	0.41 (0.18,0.60)
HD ADA SC + MTX		5.35 (1.40,22.28)	2.80 (1.21,7.36)	0.36 (0.07,0.62)
HD TOCI IV + DMARD		0.93 (0.23,3.99)	0.94 (0.32,3.16)	‐0.01 (‐0.26,0.22)
SD ANA SC + SD ETN SC + MTX		2.41 (0.61,11.84)	1.87 (0.69,5.82)	0.17 (‐0.10,0.48)
SD ANA SC + LD ETN SC + MTX		3.65 (0.85,16.59)	2.31 (0.90,6.80)	0.26 (‐0.03,0.55)
LD ADA SC + MTX	LD TOCI IV	25.53 (5.70,150.60)	12.46 (3.50,66.43)	0.46 (0.25,0.68)
LD RITUX IV + MTX		12.12 (3.02,67.88)	8.24 (2.38,43.65)	0.29 (0.14,0.48)
LD ADA IV + MTX		23.04 (2.12,238.20)	11.12 (1.92,70.61)	0.44 (0.07,0.80)
LD ABA IV + MTX		11.85 (2.79,70.60)	8.06 (2.28,45.31)	0.29 (0.12,0.50)
LD ANA SC + MTX		11.47 (1.62,90.12)	7.71 (1.51,42.95)	0.27 (0.04,0.62)
LD CERTO SC + MTX		22.25 (4.67,152.50)	11.39 (3.16,62.75)	0.44 (0.19,0.70)
LD ETN SC + MTX		20.54 (4.45,112.80)	10.99 (3.07,57.41)	0.41 (0.19,0.64)
LD GOLI IV + MTX		11.71 (2.39,76.13)	8.05 (2.04,42.32)	0.28 (0.09,0.55)
LD TOCI IV + MTX		9.40 (2.06,49.65)	6.78 (1.84,32.50)	0.23 (0.07,0.47)
LD TOFA PO + MTX		19.86 (3.10,146.10)	10.62 (2.49,64.70)	0.40 (0.12,0.70)
HD TOCI IV		14.93 (3.90,75.23)	9.42 (2.87,47.66)	0.34 (0.20,0.48)
HD TOFA PO		15.66 (3.47,102.30)	9.71 (2.62,55.93)	0.35 (0.18,0.53)
HD ADA SC		7.35 (1.51,48.47)	5.80 (1.44,33.74)	0.19 (0.05,0.36)
HD ETN SC		11.19 (2.44,60.78)	7.80 (2.04,39.32)	0.27 (0.10,0.49)
HD GOLI SC		14.83 (3.29,82.73)	9.44 (2.55,47.97)	0.33 (0.15,0.53)
HD ABA SC		22.78 (3.05,200.40)	11.47 (2.48,66.75)	0.43 (0.14,0.75)
HD INF IV + MTX		28.18 (6.73,162.10)	13.13 (3.77,69.26)	0.49 (0.30,0.68)
HD TOCI IV + MTX		26.62 (6.91,137.90)	12.86 (3.88,65.61)	0.48 (0.30,0.65)
HD TOFA PO + MTX		28.74 (6.44,171.10)	13.26 (3.78,73.25)	0.50 (0.29,0.69)
HD GOLI SC + MTX		27.56 (5.96,166.40)	12.94 (3.59,69.76)	0.49 (0.27,0.69)
HD CERTO SC + MTX		38.93 (9.22,211.20)	15.06 (4.51,77.16)	0.57 (0.37,0.74)
HD ADA SC + MTX		32.21 (6.08,214.40)	13.87 (3.73,74.13)	0.52 (0.26,0.76)
HD TOCI IV + DMARD		5.61 (1.03,35.62)	4.66 (1.03,26.81)	0.14 (0.00,0.37)
SD ANA SC + SD ETN SC + MTX		15.09 (2.41,97.04)	9.22 (2.04,48.43)	0.33 (0.10,0.62)
SD ANA SC + LD ETN SC + MTX		22.49 (3.81,146.20)	11.54 (2.87,63.49)	0.44 (0.16,0.70)
LD RITUX IV + MTX	LD ADA SC + MTX	0.49 (0.20,1.16)	0.67 (0.41,1.09)	‐0.17 (‐0.37,0.04)
LD ADA IV + MTX		0.90 (0.15,4.77)	0.95 (0.27,1.84)	‐0.02 (‐0.38,0.34)
LD ABA IV + MTX		0.47 (0.19,1.20)	0.66 (0.37,1.11)	‐0.17 (‐0.37,0.04)
LD ANA SC + MTX		0.44 (0.10,2.00)	0.63 (0.21,1.39)	‐0.18 (‐0.47,0.16)
LD CERTO SC + MTX		0.90 (0.28,3.03)	0.95 (0.50,1.70)	‐0.02 (‐0.29,0.25)
LD ETN SC + MTX		0.80 (0.26,2.32)	0.90 (0.50,1.53)	‐0.05 (‐0.31,0.20)
LD GOLI IV + MTX		0.46 (0.15,1.53)	0.64 (0.30,1.24)	‐0.18 (‐0.43,0.10)
LD TOCI IV + MTX		0.37 (0.11,1.16)	0.56 (0.24,1.10)	‐0.22 (‐0.47,0.04)
LD TOFA PO + MTX		0.76 (0.19,2.96)	0.88 (0.36,1.62)	‐0.06 (‐0.36,0.25)
HD TOCI IV		0.59 (0.26,1.36)	0.75 (0.50,1.21)	‐0.13 (‐0.32,0.07)
HD TOFA PO		0.64 (0.20,1.86)	0.79 (0.43,1.44)	‐0.11 (‐0.37,0.15)
HD ADA SC		0.29 (0.09,0.98)	0.46 (0.23,0.98)	‐0.27 (‐0.52,‐0.01)
HD ETN SC		0.44 (0.17,1.15)	0.62 (0.34,1.09)	‐0.19 (‐0.41,0.03)
HD GOLI SC		0.58 (0.21,1.64)	0.75 (0.44,1.31)	‐0.13 (‐0.36,0.12)
HD ABA SC		0.89 (0.16,4.91)	0.95 (0.36,2.08)	‐0.03 (‐0.41,0.37)
HD INF IV + MTX		1.11 (0.47,2.56)	1.05 (0.71,1.63)	0.03 (‐0.18,0.23)
HD TOCI IV + MTX		1.05 (0.45,2.46)	1.02 (0.70,1.62)	0.01 (‐0.18,0.22)
HD TOFA PO + MTX		1.15 (0.48,2.67)	1.06 (0.72,1.65)	0.03 (‐0.18,0.23)
HD GOLI SC + MTX		1.07 (0.45,2.77)	1.03 (0.68,1.67)	0.02 (‐0.19,0.24)
HD CERTO SC + MTX		1.55 (0.62,3.71)	1.20 (0.83,1.87)	0.10 (‐0.11,0.30)
HD ADA SC + MTX		1.26 (0.50,3.32)	1.10 (0.70,1.67)	0.05 (‐0.16,0.27)
HD TOCI IV + DMARD		0.22 (0.06,0.79)	0.37 (0.15,0.87)	‐0.32 (‐0.55,‐0.05)
SD ANA SC + SD ETN SC + MTX		0.57 (0.17,2.15)	0.74 (0.34,1.46)	‐0.13 (‐0.40,0.18)
SD ANA SC + LD ETN SC + MTX		0.86 (0.25,2.99)	0.93 (0.46,1.64)	‐0.04 (‐0.32,0.26)
LD ADA IV + MTX	LD RITUX IV + MTX	1.85 (0.28,10.98)	1.41 (0.40,3.03)	0.14 (‐0.22,0.52)
LD ABA IV + MTX		0.98 (0.43,2.26)	0.99 (0.56,1.67)	0.00 (‐0.18,0.18)
LD ANA SC + MTX		0.91 (0.22,4.20)	0.94 (0.30,2.19)	‐0.02 (‐0.27,0.33)
LD CERTO SC + MTX		1.86 (0.65,5.46)	1.42 (0.75,2.53)	0.15 (‐0.10,0.39)
LD ETN SC + MTX		1.62 (0.65,4.27)	1.33 (0.76,2.35)	0.11 (‐0.10,0.33)
LD GOLI IV + MTX		0.96 (0.32,2.91)	0.97 (0.44,1.87)	‐0.01 (‐0.23,0.25)
LD TOCI IV + MTX		0.77 (0.26,2.21)	0.84 (0.37,1.70)	‐0.05 (‐0.27,0.17)
LD TOFA PO + MTX		1.58 (0.46,5.37)	1.31 (0.59,2.45)	0.11 (‐0.16,0.39)
HD TOCI IV		1.21 (0.60,2.57)	1.12 (0.74,1.88)	0.04 (‐0.12,0.21)
HD TOFA PO		1.30 (0.45,3.67)	1.17 (0.62,2.39)	0.06 (‐0.19,0.28)
HD ADA SC		0.60 (0.21,1.86)	0.70 (0.33,1.58)	‐0.10 (‐0.32,0.12)
HD ETN SC		0.91 (0.36,2.17)	0.94 (0.51,1.66)	‐0.02 (‐0.22,0.17)
HD GOLI SC		1.19 (0.47,3.01)	1.12 (0.63,2.04)	0.04 (‐0.17,0.25)
HD ABA SC		1.83 (0.37,10.53)	1.41 (0.52,3.31)	0.14 (‐0.21,0.52)
HD INF IV + MTX		2.29 (1.04,5.06)	1.57 (1.02,2.56)	0.19 (0.01,0.37)
HD TOCI IV + MTX		2.19 (1.06,4.52)	1.55 (1.03,2.50)	0.18 (0.01,0.35)
HD TOFA PO + MTX		2.36 (1.10,5.07)	1.59 (1.05,2.61)	0.20 (0.02,0.37)
HD GOLI SC + MTX		2.24 (0.93,5.53)	1.56 (0.96,2.66)	0.19 (‐0.02,0.39)
HD CERTO SC + MTX		3.14 (1.49,6.76)	1.77 (1.23,2.94)	0.27 (0.10,0.44)
HD ADA SC + MTX		2.59 (0.92,8.01)	1.65 (0.95,2.92)	0.22 (‐0.02,0.47)
HD TOCI IV + DMARD		0.45 (0.15,1.41)	0.56 (0.22,1.26)	‐0.14 (‐0.34,0.07)
SD ANA SC + SD ETN SC + MTX		1.19 (0.38,4.01)	1.11 (0.50,2.21)	0.04 (‐0.20,0.33)
SD ANA SC + LD ETN SC + MTX		1.78 (0.54,5.67)	1.40 (0.66,2.56)	0.13 (‐0.13,0.40)
LD ABA IV + MTX	LD ADA IV + MTX	0.53 (0.09,3.69)	0.70 (0.32,2.65)	‐0.15 (‐0.52,0.24)
LD ANA SC + MTX		0.50 (0.06,4.61)	0.68 (0.19,2.88)	‐0.15 (‐0.59,0.29)
LD CERTO SC + MTX		1.01 (0.15,7.25)	1.00 (0.43,3.59)	0.00 (‐0.42,0.41)
LD ETN SC + MTX		0.91 (0.13,6.17)	0.95 (0.41,3.56)	‐0.02 (‐0.43,0.37)
LD GOLI IV + MTX		0.53 (0.08,4.13)	0.69 (0.26,2.63)	‐0.14 (‐0.55,0.27)
LD TOCI IV + MTX		0.42 (0.07,3.01)	0.60 (0.23,2.37)	‐0.19 (‐0.57,0.20)
LD TOFA PO + MTX		0.86 (0.12,7.05)	0.93 (0.32,3.49)	‐0.04 (‐0.46,0.40)
HD TOCI IV		0.67 (0.12,4.36)	0.80 (0.42,2.94)	‐0.10 (‐0.46,0.26)
HD TOFA PO		0.70 (0.11,5.26)	0.83 (0.39,3.27)	‐0.09 (‐0.47,0.32)
HD ADA SC		0.32 (0.05,2.46)	0.49 (0.22,2.01)	‐0.25 (‐0.61,0.15)
HD ETN SC		0.50 (0.08,3.29)	0.67 (0.29,2.46)	‐0.16 (‐0.53,0.21)
HD GOLI SC		0.66 (0.11,4.61)	0.80 (0.37,2.91)	‐0.10 (‐0.48,0.28)
HD ABA SC		0.97 (0.11,12.73)	0.98 (0.34,4.67)	‐0.01 (‐0.49,0.52)
HD INF IV + MTX		1.25 (0.21,8.23)	1.11 (0.59,4.10)	0.05 (‐0.33,0.42)
HD TOCI IV + MTX		1.18 (0.22,7.94)	1.08 (0.59,4.02)	0.04 (‐0.32,0.42)
HD TOFA PO + MTX		1.29 (0.24,7.85)	1.12 (0.61,3.92)	0.06 (‐0.30,0.42)
HD GOLI SC + MTX		1.21 (0.22,8.24)	1.09 (0.58,4.04)	0.05 (‐0.32,0.42)
HD CERTO SC + MTX		1.73 (0.31,10.93)	1.27 (0.68,4.58)	0.13 (‐0.24,0.49)
HD ADA SC + MTX		1.40 (0.23,12.60)	1.16 (0.55,4.66)	0.08 (‐0.33,0.50)
HD TOCI IV + DMARD		0.26 (0.03,2.01)	0.41 (0.13,1.71)	‐0.28 (‐0.67,0.11)
SD ANA SC + SD ETN SC + MTX		0.67 (0.09,5.59)	0.80 (0.30,3.00)	‐0.09 (‐0.52,0.34)
SD ANA SC + LD ETN SC + MTX		0.99 (0.13,7.58)	1.00 (0.39,3.57)	0.00 (‐0.44,0.42)
LD ANA SC + MTX	LD ABA IV + MTX	0.91 (0.20,4.66)	0.94 (0.29,2.52)	‐0.02 (‐0.29,0.34)
LD CERTO SC + MTX		1.91 (0.63,6.04)	1.45 (0.74,2.79)	0.15 (‐0.10,0.41)
LD ETN SC + MTX		1.70 (0.57,4.75)	1.36 (0.71,2.52)	0.12 (‐0.13,0.36)
LD GOLI IV + MTX		0.97 (0.32,2.95)	0.98 (0.45,1.98)	‐0.01 (‐0.24,0.24)
LD TOCI IV + MTX		0.78 (0.24,2.42)	0.84 (0.35,1.81)	‐0.05 (‐0.29,0.19)
LD TOFA PO + MTX		1.61 (0.43,6.11)	1.32 (0.56,2.75)	0.11 (‐0.17,0.41)
HD TOCI IV		1.23 (0.55,2.86)	1.14 (0.71,2.11)	0.05 (‐0.14,0.22)
HD TOFA PO		1.32 (0.42,3.99)	1.19 (0.60,2.58)	0.06 (‐0.20,0.30)
HD ADA SC		0.61 (0.20,2.00)	0.70 (0.33,1.66)	‐0.10 (‐0.34,0.14)
HD ETN SC		0.91 (0.35,2.36)	0.94 (0.49,1.82)	‐0.02 (‐0.24,0.18)
HD GOLI SC		1.22 (0.46,3.29)	1.14 (0.62,2.17)	0.04 (‐0.18,0.26)
HD ABA SC		1.78 (0.34,11.27)	1.40 (0.49,3.73)	0.13 (‐0.24,0.53)
HD INF IV + MTX		2.33 (0.99,5.52)	1.59 (1.00,2.82)	0.20 (0.00,0.39)
HD TOCI IV + MTX		2.21 (0.98,5.30)	1.56 (0.99,2.86)	0.19 (0.00,0.37)
HD TOFA PO + MTX		2.39 (1.03,5.58)	1.61 (1.01,2.78)	0.20 (0.01,0.39)
HD GOLI SC + MTX		2.27 (0.91,5.99)	1.56 (0.95,2.89)	0.19 (‐0.02,0.40)
HD CERTO SC + MTX		3.21 (1.37,7.60)	1.81 (1.17,3.32)	0.27 (0.08,0.46)
HD ADA SC + MTX		2.67 (0.86,8.46)	1.67 (0.92,3.16)	0.23 (‐0.03,0.48)
HD TOCI IV + DMARD		0.45 (0.14,1.69)	0.57 (0.22,1.43)	‐0.14 (‐0.36,0.11)
SD ANA SC + SD ETN SC + MTX		1.20 (0.34,4.46)	1.12 (0.47,2.44)	0.04 (‐0.23,0.34)
SD ANA SC + LD ETN SC + MTX		1.79 (0.53,6.53)	1.40 (0.67,2.80)	0.13 (‐0.14,0.42)
LD CERTO SC + MTX	LD ANA SC + MTX	2.06 (0.40,9.99)	1.51 (0.63,4.88)	0.16 (‐0.21,0.47)
LD ETN SC + MTX		1.78 (0.36,8.78)	1.41 (0.60,4.58)	0.13 (‐0.24,0.43)
LD GOLI IV + MTX		1.04 (0.21,5.34)	1.03 (0.39,3.31)	0.01 (‐0.35,0.33)
LD TOCI IV + MTX		0.84 (0.16,4.23)	0.89 (0.31,2.97)	‐0.04 (‐0.40,0.26)
LD TOFA PO + MTX		1.72 (0.27,11.39)	1.37 (0.46,5.08)	0.12 (‐0.28,0.49)
HD TOCI IV		1.33 (0.33,5.28)	1.20 (0.57,3.73)	0.07 (‐0.26,0.30)
HD TOFA PO		1.41 (0.29,6.98)	1.24 (0.52,4.38)	0.08 (‐0.29,0.36)
HD ADA SC		0.65 (0.13,3.66)	0.74 (0.28,2.91)	‐0.08 (‐0.45,0.20)
HD ETN SC		0.98 (0.21,4.57)	0.99 (0.40,3.28)	0.00 (‐0.35,0.28)
HD GOLI SC		1.30 (0.28,6.49)	1.18 (0.52,3.96)	0.06 (‐0.30,0.35)
HD ABA SC		2.01 (0.23,17.30)	1.49 (0.43,5.94)	0.15 (‐0.34,0.59)
HD INF IV + MTX		2.52 (0.57,10.48)	1.68 (0.78,5.22)	0.21 (‐0.14,0.48)
HD TOCI IV + MTX		2.39 (0.53,10.14)	1.64 (0.76,5.12)	0.20 (‐0.15,0.46)
HD TOFA PO + MTX		2.56 (0.57,11.78)	1.68 (0.78,5.35)	0.22 (‐0.13,0.50)
HD GOLI SC + MTX		2.46 (0.52,11.41)	1.66 (0.73,5.36)	0.21 (‐0.16,0.50)
HD CERTO SC + MTX		3.48 (0.80,14.93)	1.93 (0.93,5.96)	0.29 (‐0.05,0.55)
HD ADA SC + MTX		2.87 (0.57,14.52)	1.73 (0.77,5.56)	0.24 (‐0.14,0.55)
HD TOCI IV + DMARD		0.50 (0.09,2.44)	0.60 (0.19,2.03)	‐0.12 (‐0.48,0.14)
SD ANA SC + SD ETN SC + MTX		1.34 (0.24,7.63)	1.19 (0.43,4.02)	0.06 (‐0.32,0.40)
SD ANA SC + LD ETN SC + MTX		1.96 (0.34,11.07)	1.46 (0.55,4.94)	0.15 (‐0.25,0.49)
LD ETN SC + MTX	LD CERTO SC + MTX	0.87 (0.25,2.86)	0.93 (0.50,1.83)	‐0.03 (‐0.32,0.24)
LD GOLI IV + MTX		0.52 (0.14,1.99)	0.69 (0.30,1.49)	‐0.15 (‐0.43,0.16)
LD TOCI IV + MTX		0.41 (0.10,1.53)	0.59 (0.24,1.31)	‐0.20 (‐0.49,0.09)
LD TOFA PO + MTX		0.86 (0.19,3.62)	0.92 (0.37,1.95)	‐0.04 (‐0.36,0.29)
HD TOCI IV		0.66 (0.22,1.84)	0.80 (0.48,1.51)	‐0.10 (‐0.35,0.13)
HD TOFA PO		0.70 (0.17,2.49)	0.83 (0.42,1.81)	‐0.09 (‐0.41,0.20)
HD ADA SC		0.32 (0.08,1.30)	0.48 (0.23,1.19)	‐0.25 (‐0.54,0.05)
HD ETN SC		0.48 (0.16,1.57)	0.66 (0.34,1.35)	‐0.16 (‐0.42,0.10)
HD GOLI SC		0.64 (0.19,2.11)	0.79 (0.43,1.60)	‐0.11 (‐0.39,0.17)
HD ABA SC		0.98 (0.16,6.38)	0.99 (0.36,2.50)	0.00 (‐0.41,0.42)
HD INF IV + MTX		1.22 (0.42,3.54)	1.10 (0.69,2.09)	0.05 (‐0.20,0.29)
HD TOCI IV + MTX		1.18 (0.41,3.38)	1.09 (0.68,2.04)	0.04 (‐0.21,0.28)
HD TOFA PO + MTX		1.27 (0.43,3.74)	1.12 (0.70,2.08)	0.06 (‐0.20,0.30)
HD GOLI SC + MTX		1.20 (0.39,3.86)	1.09 (0.65,2.10)	0.04 (‐0.22,0.32)
HD CERTO SC + MTX		1.70 (0.68,4.09)	1.26 (0.86,2.19)	0.13 (‐0.09,0.33)
HD ADA SC + MTX		1.42 (0.37,5.40)	1.16 (0.62,2.27)	0.08 (‐0.23,0.38)
HD TOCI IV + DMARD		0.24 (0.06,0.97)	0.40 (0.15,0.97)	‐0.29 (‐0.57,‐0.01)
SD ANA SC + SD ETN SC + MTX		0.64 (0.15,2.60)	0.79 (0.33,1.71)	‐0.10 (‐0.42,0.22)
SD ANA SC + LD ETN SC + MTX		0.97 (0.22,3.75)	0.98 (0.45,1.98)	‐0.01 (‐0.34,0.31)
LD GOLI IV + MTX	LD ETN SC + MTX	0.58 (0.17,2.03)	0.73 (0.33,1.52)	‐0.12 (‐0.38,0.17)
LD TOCI IV + MTX		0.46 (0.13,1.54)	0.63 (0.26,1.33)	‐0.17 (‐0.43,0.10)
LD TOFA PO + MTX		0.98 (0.24,4.00)	0.99 (0.39,2.06)	0.00 (‐0.32,0.32)
HD TOCI IV		0.74 (0.30,1.94)	0.84 (0.53,1.54)	‐0.07 (‐0.29,0.15)
HD TOFA PO		0.79 (0.21,2.56)	0.88 (0.45,1.77)	‐0.06 (‐0.36,0.22)
HD ADA SC		0.36 (0.10,1.25)	0.52 (0.25,1.17)	‐0.22 (‐0.49,0.05)
HD ETN SC		0.54 (0.19,1.60)	0.69 (0.38,1.35)	‐0.14 (‐0.37,0.10)
HD GOLI SC		0.73 (0.25,2.18)	0.84 (0.47,1.61)	‐0.07 (‐0.31,0.18)
HD ABA SC		1.11 (0.20,6.49)	1.06 (0.38,2.51)	0.03 (‐0.37,0.42)
HD INF IV + MTX		1.40 (0.54,3.72)	1.18 (0.75,2.06)	0.08 (‐0.15,0.31)
HD TOCI IV + MTX		1.33 (0.50,3.47)	1.15 (0.73,2.07)	0.07 (‐0.16,0.29)
HD TOFA PO + MTX		1.44 (0.52,3.90)	1.19 (0.73,2.14)	0.09 (‐0.16,0.32)
HD GOLI SC + MTX		1.37 (0.48,4.04)	1.16 (0.71,2.10)	0.08 (‐0.17,0.33)
HD CERTO SC + MTX		1.92 (0.74,5.30)	1.34 (0.88,2.42)	0.16 (‐0.07,0.38)
HD ADA SC + MTX		1.58 (0.46,5.79)	1.23 (0.68,2.37)	0.11 (‐0.18,0.39)
HD TOCI IV + DMARD		0.27 (0.08,1.05)	0.42 (0.16,1.04)	‐0.26 (‐0.51,0.01)
SD ANA SC + SD ETN SC + MTX		0.73 (0.21,2.58)	0.83 (0.37,1.70)	‐0.07 (‐0.34,0.23)
SD ANA SC + LD ETN SC + MTX		1.08 (0.33,3.87)	1.04 (0.52,2.01)	0.02 (‐0.26,0.31)
LD TOCI IV + MTX	LD GOLI IV + MTX	0.79 (0.20,3.00)	0.85 (0.33,2.15)	‐0.05 (‐0.33,0.22)
LD TOFA PO + MTX		1.68 (0.34,7.25)	1.36 (0.50,3.21)	0.12 (‐0.23,0.44)
HD TOCI IV		1.27 (0.42,3.58)	1.17 (0.62,2.48)	0.05 (‐0.21,0.26)
HD TOFA PO		1.35 (0.36,4.50)	1.20 (0.57,2.84)	0.07 (‐0.24,0.31)
HD ADA SC		0.62 (0.16,2.42)	0.72 (0.30,1.92)	‐0.09 (‐0.39,0.16)
HD ETN SC		0.93 (0.28,3.25)	0.95 (0.46,2.26)	‐0.02 (‐0.29,0.23)
HD GOLI SC		1.24 (0.41,3.80)	1.15 (0.59,2.48)	0.05 (‐0.21,0.28)
HD ABA SC		1.89 (0.32,12.68)	1.44 (0.49,4.06)	0.15 (‐0.25,0.54)
HD INF IV + MTX		2.35 (0.82,7.16)	1.62 (0.90,3.50)	0.20 (‐0.05,0.43)
HD TOCI IV + MTX		2.28 (0.77,6.69)	1.59 (0.88,3.39)	0.19 (‐0.06,0.41)
HD TOFA PO + MTX		2.46 (0.75,7.74)	1.63 (0.87,3.64)	0.21 (‐0.07,0.44)
HD GOLI SC + MTX		2.32 (0.75,7.19)	1.59 (0.87,3.49)	0.20 (‐0.07,0.44)
HD CERTO SC + MTX		3.29 (1.08,10.01)	1.84 (1.03,4.04)	0.28 (0.02,0.50)
HD ADA SC + MTX		2.72 (0.72,9.55)	1.70 (0.84,3.75)	0.23 (‐0.08,0.50)
HD TOCI IV + DMARD		0.46 (0.12,1.91)	0.57 (0.21,1.61)	‐0.13 (‐0.41,0.12)
SD ANA SC + SD ETN SC + MTX		1.25 (0.29,5.44)	1.15 (0.45,2.89)	0.05 (‐0.26,0.38)
SD ANA SC + LD ETN SC + MTX		1.83 (0.46,7.74)	1.41 (0.62,3.45)	0.14 (‐0.18,0.44)
LD TOFA PO + MTX	LD TOCI IV + MTX	2.10 (0.44,9.63)	1.57 (0.56,3.92)	0.16 (‐0.16,0.49)
HD TOCI IV		1.60 (0.63,4.23)	1.36 (0.77,2.90)	0.10 (‐0.11,0.28)
HD TOFA PO		1.70 (0.51,5.90)	1.41 (0.66,3.53)	0.12 (‐0.16,0.35)
HD ADA SC		0.77 (0.23,2.91)	0.83 (0.35,2.29)	‐0.05 (‐0.30,0.19)
HD ETN SC		1.17 (0.38,4.05)	1.12 (0.52,2.73)	0.03 (‐0.22,0.29)
HD GOLI SC		1.55 (0.49,5.07)	1.33 (0.63,3.18)	0.09 (‐0.16,0.34)
HD ABA SC		2.40 (0.42,15.15)	1.68 (0.56,5.08)	0.19 (‐0.19,0.57)
HD INF IV + MTX		2.99 (1.08,9.45)	1.88 (1.04,4.25)	0.25 (0.02,0.49)
HD TOCI IV + MTX		2.87 (1.08,7.82)	1.87 (1.04,3.99)	0.24 (0.02,0.43)
HD TOFA PO + MTX		3.07 (1.00,9.38)	1.90 (1.00,4.35)	0.26 (0.00,0.48)
HD GOLI SC + MTX		2.87 (0.89,10.00)	1.85 (0.94,4.31)	0.24 (‐0.03,0.49)
HD CERTO SC + MTX		4.16 (1.36,12.90)	2.16 (1.15,4.86)	0.33 (0.07,0.55)
HD ADA SC + MTX		3.39 (0.89,13.77)	1.98 (0.93,4.69)	0.28 (‐0.03,0.56)
HD TOCI IV + DMARD		0.60 (0.16,2.30)	0.68 (0.25,1.86)	‐0.09 (‐0.34,0.16)
SD ANA SC + SD ETN SC + MTX		1.57 (0.41,6.71)	1.33 (0.55,3.50)	0.09 (‐0.19,0.42)
SD ANA SC + LD ETN SC + MTX		2.37 (0.60,10.10)	1.67 (0.71,4.07)	0.19 (‐0.11,0.50)
HD TOCI IV	LD TOFA PO + MTX	0.76 (0.22,2.84)	0.85 (0.49,2.18)	‐0.07 (‐0.35,0.21)
HD TOFA PO		0.81 (0.19,3.83)	0.89 (0.44,2.52)	‐0.05 (‐0.38,0.27)
HD ADA SC		0.37 (0.09,1.85)	0.53 (0.23,1.57)	‐0.21 (‐0.52,0.11)
HD ETN SC		0.57 (0.15,2.26)	0.71 (0.35,1.77)	‐0.13 (‐0.43,0.17)
HD GOLI SC		0.74 (0.20,3.12)	0.85 (0.44,2.15)	‐0.07 (‐0.37,0.23)
HD ABA SC		1.16 (0.16,8.45)	1.08 (0.38,3.27)	0.03 (‐0.41,0.47)
HD INF IV + MTX		1.45 (0.39,5.44)	1.20 (0.68,2.88)	0.09 (‐0.21,0.37)
HD TOCI IV + MTX		1.35 (0.40,5.29)	1.16 (0.68,2.88)	0.07 (‐0.21,0.36)
HD TOFA PO + MTX		1.48 (0.49,4.58)	1.20 (0.75,2.60)	0.09 (‐0.16,0.33)
HD GOLI SC + MTX		1.40 (0.39,5.69)	1.18 (0.66,2.85)	0.08 (‐0.22,0.39)
HD CERTO SC + MTX		2.01 (0.56,7.16)	1.37 (0.81,3.39)	0.17 (‐0.13,0.43)
HD ADA SC + MTX		1.64 (0.37,7.93)	1.25 (0.64,3.23)	0.11 (‐0.23,0.45)
HD TOCI IV + DMARD		0.28 (0.06,1.35)	0.43 (0.15,1.24)	‐0.25 (‐0.57,0.05)
SD ANA SC + SD ETN SC + MTX		0.75 (0.15,3.85)	0.85 (0.33,2.27)	‐0.07 (‐0.41,0.30)
SD ANA SC + LD ETN SC + MTX		1.14 (0.22,5.38)	1.07 (0.45,2.75)	0.03 (‐0.34,0.37)
HD TOFA PO	HD TOCI IV	1.08 (0.41,2.57)	1.05 (0.57,1.78)	0.02 (‐0.21,0.22)
HD ADA SC		0.48 (0.20,1.28)	0.61 (0.32,1.18)	‐0.15 (‐0.33,0.05)
HD ETN SC		0.74 (0.31,1.78)	0.82 (0.46,1.39)	‐0.07 (‐0.24,0.13)
HD GOLI SC		0.98 (0.42,2.30)	0.99 (0.57,1.63)	‐0.01 (‐0.19,0.20)
HD ABA SC		1.45 (0.34,7.89)	1.22 (0.48,2.68)	0.09 (‐0.24,0.46)
HD INF IV + MTX		1.88 (0.93,3.87)	1.40 (0.96,2.00)	0.15 (‐0.02,0.32)
HD TOCI IV + MTX		1.79 (1.03,3.11)	1.37 (1.02,1.82)	0.14 (0.01,0.27)
HD TOFA PO + MTX		1.94 (0.87,4.04)	1.41 (0.92,2.06)	0.16 (‐0.03,0.33)
HD GOLI SC + MTX		1.84 (0.81,4.44)	1.37 (0.88,2.08)	0.15 (‐0.05,0.35)
HD CERTO SC + MTX		2.57 (1.29,5.38)	1.59 (1.14,2.27)	0.23 (0.06,0.39)
HD ADA SC + MTX		2.17 (0.71,6.31)	1.48 (0.82,2.29)	0.19 (‐0.08,0.41)
HD TOCI IV + DMARD		0.37 (0.14,1.05)	0.49 (0.21,1.03)	‐0.19 (‐0.35,0.01)
SD ANA SC + SD ETN SC + MTX		0.98 (0.31,3.04)	0.99 (0.44,1.80)	0.00 (‐0.24,0.27)
SD ANA SC + LD ETN SC + MTX		1.46 (0.45,4.56)	1.24 (0.60,2.09)	0.09 (‐0.17,0.35)
HD ADA SC	HD TOFA PO	0.46 (0.17,1.32)	0.59 (0.29,1.21)	‐0.16 (‐0.36,0.06)
HD ETN SC		0.68 (0.23,2.29)	0.78 (0.37,1.64)	‐0.09 (‐0.30,0.19)
HD GOLI SC		0.93 (0.33,2.63)	0.96 (0.50,1.81)	‐0.02 (‐0.25,0.23)
HD ABA SC		1.42 (0.31,7.05)	1.20 (0.47,2.49)	0.09 (‐0.26,0.44)
HD INF IV + MTX		1.75 (0.64,5.29)	1.34 (0.78,2.41)	0.14 (‐0.11,0.39)
HD TOCI IV + MTX		1.69 (0.62,4.72)	1.31 (0.77,2.28)	0.13 (‐0.11,0.36)
HD TOFA PO + MTX		1.82 (0.65,5.22)	1.36 (0.79,2.36)	0.15 (‐0.10,0.38)
HD GOLI SC + MTX		1.73 (0.57,5.23)	1.33 (0.72,2.37)	0.13 (‐0.14,0.39)
HD CERTO SC + MTX		2.44 (0.87,7.25)	1.53 (0.93,2.65)	0.22 (‐0.03,0.45)
HD ADA SC + MTX		2.00 (0.55,7.96)	1.42 (0.70,2.61)	0.17 (‐0.14,0.46)
HD TOCI IV + DMARD		0.35 (0.09,1.29)	0.48 (0.17,1.17)	‐0.21 (‐0.41,0.05)
SD ANA SC + SD ETN SC + MTX		0.91 (0.24,3.71)	0.95 (0.38,1.96)	‐0.02 (‐0.30,0.31)
SD ANA SC + LD ETN SC + MTX		1.36 (0.35,5.27)	1.18 (0.51,2.29)	0.07 (‐0.23,0.39)
HD ETN SC	HD ADA SC	1.54 (0.43,4.77)	1.36 (0.54,2.89)	0.08 (‐0.16,0.32)
HD GOLI SC		2.03 (0.61,6.02)	1.63 (0.71,3.38)	0.15 (‐0.10,0.38)
HD ABA SC		3.03 (0.62,15.42)	2.02 (0.72,4.66)	0.24 (‐0.09,0.58)
HD INF IV + MTX		3.85 (1.22,11.95)	2.29 (1.13,4.47)	0.30 (0.04,0.53)
HD TOCI IV + MTX		3.68 (1.26,10.12)	2.24 (1.15,4.29)	0.29 (0.05,0.49)
HD TOFA PO + MTX		3.93 (1.33,11.68)	2.30 (1.19,4.49)	0.31 (0.07,0.53)
HD GOLI SC + MTX		3.78 (1.11,11.88)	2.26 (1.07,4.47)	0.30 (0.02,0.54)
HD CERTO SC + MTX		5.31 (1.67,15.81)	2.61 (1.36,4.92)	0.38 (0.12,0.59)
HD ADA SC + MTX		4.34 (1.09,16.97)	2.39 (1.06,4.78)	0.33 (0.02,0.60)
HD TOCI IV + DMARD		0.75 (0.21,2.89)	0.80 (0.28,2.17)	‐0.05 (‐0.24,0.21)
SD ANA SC + SD ETN SC + MTX		2.00 (0.46,7.90)	1.60 (0.56,3.66)	0.14 (‐0.14,0.46)
SD ANA SC + LD ETN SC + MTX		3.04 (0.69,11.57)	2.01 (0.77,4.17)	0.24 (‐0.07,0.54)
HD GOLI SC	HD ETN SC	1.34 (0.49,3.53)	1.21 (0.63,2.32)	0.06 (‐0.16,0.29)
HD ABA SC		2.05 (0.39,11.60)	1.52 (0.54,3.72)	0.16 (‐0.21,0.53)
HD INF IV + MTX		2.55 (1.06,6.32)	1.68 (1.03,3.03)	0.22 (0.01,0.41)
HD TOCI IV + MTX		2.44 (0.96,5.82)	1.66 (0.98,3.02)	0.21 (‐0.01,0.39)
HD TOFA PO + MTX		2.62 (1.03,6.51)	1.72 (1.01,3.00)	0.22 (0.01,0.43)
HD GOLI SC + MTX		2.51 (0.93,6.81)	1.68 (0.96,3.12)	0.21 (‐0.02,0.43)
HD CERTO SC + MTX		3.52 (1.39,8.85)	1.93 (1.19,3.43)	0.29 (0.08,0.49)
HD ADA SC + MTX		2.91 (0.85,9.56)	1.78 (0.91,3.37)	0.24 (‐0.04,0.50)
HD TOCI IV + DMARD		0.51 (0.15,1.74)	0.61 (0.23,1.48)	‐0.12 (‐0.36,0.11)
SD ANA SC + SD ETN SC + MTX		1.31 (0.37,4.89)	1.19 (0.50,2.49)	0.06 (‐0.20,0.35)
SD ANA SC + LD ETN SC + MTX		1.98 (0.56,6.95)	1.49 (0.69,2.97)	0.15 (‐0.13,0.44)
HD ABA SC	HD GOLI SC	1.53 (0.30,8.55)	1.26 (0.47,2.95)	0.10 (‐0.27,0.48)
HD INF IV + MTX		1.93 (0.76,4.66)	1.41 (0.87,2.35)	0.16 (‐0.06,0.36)
HD TOCI IV + MTX		1.83 (0.77,4.34)	1.38 (0.86,2.35)	0.14 (‐0.06,0.34)
HD TOFA PO + MTX		1.97 (0.74,4.83)	1.43 (0.85,2.41)	0.16 (‐0.07,0.37)
HD GOLI SC + MTX		1.88 (0.78,4.38)	1.39 (0.88,2.23)	0.15 (‐0.06,0.35)
HD CERTO SC + MTX		2.63 (1.05,6.51)	1.60 (1.02,2.68)	0.23 (0.01,0.43)
HD ADA SC + MTX		2.19 (0.68,7.50)	1.48 (0.80,2.66)	0.19 (‐0.09,0.45)
HD TOCI IV + DMARD		0.38 (0.11,1.36)	0.50 (0.20,1.23)	‐0.19 (‐0.42,0.07)
SD ANA SC + SD ETN SC + MTX		0.98 (0.28,3.66)	0.99 (0.42,2.02)	0.00 (‐0.27,0.31)
SD ANA SC + LD ETN SC + MTX		1.50 (0.41,5.27)	1.25 (0.58,2.36)	0.10 (‐0.20,0.38)
HD INF IV + MTX	HD ABA SC	1.28 (0.24,6.28)	1.12 (0.54,2.82)	0.06 (‐0.33,0.41)
HD TOCI IV + MTX		1.22 (0.21,5.94)	1.10 (0.51,2.87)	0.05 (‐0.36,0.40)
HD TOFA PO + MTX		1.30 (0.24,6.77)	1.13 (0.55,2.99)	0.06 (‐0.33,0.43)
HD GOLI SC + MTX		1.26 (0.22,6.45)	1.11 (0.50,2.97)	0.06 (‐0.35,0.42)
HD CERTO SC + MTX		1.73 (0.30,8.54)	1.27 (0.65,3.26)	0.13 (‐0.26,0.48)
HD ADA SC + MTX		1.43 (0.22,8.63)	1.17 (0.52,3.08)	0.08 (‐0.34,0.48)
HD TOCI IV + DMARD		0.25 (0.04,1.54)	0.40 (0.12,1.32)	‐0.28 (‐0.65,0.09)
SD ANA SC + SD ETN SC + MTX		0.66 (0.09,3.85)	0.80 (0.28,2.18)	‐0.10 (‐0.52,0.31)
SD ANA SC + LD ETN SC + MTX		1.00 (0.14,5.90)	1.00 (0.38,2.72)	0.00 (‐0.44,0.40)
HD TOCI IV + MTX	HD INF IV + MTX	0.95 (0.45,2.05)	0.98 (0.69,1.41)	‐0.01 (‐0.19,0.17)
HD TOFA PO + MTX		1.04 (0.45,2.32)	1.02 (0.69,1.49)	0.01 (‐0.19,0.20)
HD GOLI SC + MTX		0.97 (0.40,2.34)	0.99 (0.64,1.48)	‐0.01 (‐0.22,0.20)
HD CERTO SC + MTX		1.38 (0.63,2.98)	1.14 (0.82,1.62)	0.08 (‐0.11,0.25)
HD ADA SC + MTX		1.14 (0.38,3.46)	1.06 (0.61,1.65)	0.03 (‐0.23,0.28)
HD TOCI IV + DMARD		0.19 (0.06,0.65)	0.35 (0.14,0.79)	‐0.34 (‐0.55,‐0.10)
SD ANA SC + SD ETN SC + MTX		0.51 (0.16,1.69)	0.71 (0.32,1.29)	‐0.16 (‐0.40,0.12)
SD ANA SC + LD ETN SC + MTX		0.78 (0.26,2.44)	0.89 (0.44,1.47)	‐0.06 (‐0.31,0.21)
HD TOFA PO + MTX	HD TOCI IV + MTX	1.08 (0.50,2.43)	1.04 (0.70,1.49)	0.02 (‐0.17,0.21)
HD GOLI SC + MTX		1.03 (0.44,2.50)	1.01 (0.66,1.50)	0.01 (‐0.20,0.22)
HD CERTO SC + MTX		1.43 (0.67,3.18)	1.16 (0.84,1.65)	0.09 (‐0.10,0.27)
HD ADA SC + MTX		1.19 (0.41,3.65)	1.08 (0.62,1.65)	0.04 (‐0.21,0.28)
HD TOCI IV + DMARD		0.21 (0.07,0.66)	0.36 (0.15,0.79)	‐0.33 (‐0.52,‐0.10)
SD ANA SC + SD ETN SC + MTX		0.55 (0.18,1.81)	0.73 (0.33,1.31)	‐0.14 (‐0.38,0.15)
SD ANA SC + LD ETN SC + MTX		0.81 (0.25,2.63)	0.91 (0.43,1.54)	‐0.05 (‐0.32,0.23)
HD GOLI SC + MTX	HD TOFA PO + MTX	0.95 (0.37,2.42)	0.98 (0.62,1.49)	‐0.01 (‐0.23,0.21)
HD CERTO SC + MTX		1.34 (0.62,2.99)	1.12 (0.81,1.63)	0.07 (‐0.12,0.25)
HD ADA SC + MTX		1.09 (0.39,3.55)	1.04 (0.61,1.63)	0.02 (‐0.22,0.28)
HD TOCI IV + DMARD		0.19 (0.06,0.68)	0.35 (0.14,0.80)	‐0.35 (‐0.56,‐0.09)
SD ANA SC + SD ETN SC + MTX		0.51 (0.15,1.83)	0.70 (0.31,1.31)	‐0.16 (‐0.43,0.14)
SD ANA SC + LD ETN SC + MTX		0.76 (0.21,2.54)	0.88 (0.42,1.51)	‐0.07 (‐0.35,0.22)
HD CERTO SC + MTX	HD GOLI SC + MTX	1.42 (0.58,3.45)	1.15 (0.80,1.76)	0.08 (‐0.13,0.29)
HD ADA SC + MTX		1.17 (0.37,3.71)	1.07 (0.59,1.75)	0.04 (‐0.24,0.29)
HD TOCI IV + DMARD		0.20 (0.06,0.71)	0.36 (0.14,0.82)	‐0.33 (‐0.57,‐0.08)
SD ANA SC + SD ETN SC + MTX		0.53 (0.15,1.94)	0.72 (0.31,1.39)	‐0.15 (‐0.42,0.15)
SD ANA SC + LD ETN SC + MTX		0.80 (0.23,2.79)	0.90 (0.42,1.57)	‐0.05 (‐0.34,0.23)
HD ADA SC + MTX	HD CERTO SC + MTX	0.82 (0.28,2.59)	0.93 (0.54,1.40)	‐0.05 (‐0.30,0.20)
HD TOCI IV + DMARD		0.14 (0.05,0.46)	0.31 (0.13,0.67)	‐0.42 (‐0.61,‐0.18)
SD ANA SC + SD ETN SC + MTX		0.38 (0.11,1.26)	0.62 (0.28,1.11)	‐0.23 (‐0.49,0.05)
SD ANA SC + LD ETN SC + MTX		0.56 (0.17,1.96)	0.78 (0.38,1.28)	‐0.14 (‐0.41,0.15)
HD TOCI IV + DMARD	HD ADA SC + MTX	0.17 (0.04,0.77)	0.34 (0.13,0.85)	‐0.37 (‐0.63,‐0.06)
SD ANA SC + SD ETN SC + MTX		0.46 (0.11,1.88)	0.67 (0.30,1.39)	‐0.18 (‐0.48,0.15)
SD ANA SC + LD ETN SC + MTX		0.69 (0.17,2.78)	0.84 (0.40,1.62)	‐0.08 (‐0.40,0.24)
SD ANA SC + SD ETN SC + MTX	HD TOCI IV + DMARD	2.66 (0.61,11.12)	1.99 (0.70,5.51)	0.18 (‐0.10,0.48)
SD ANA SC + LD ETN SC + MTX		3.96 (0.90,15.38)	2.47 (0.94,6.49)	0.28 (‐0.02,0.56)
SD ANA SC + LD ETN SC + MTX	SD ANA SC + SD ETN SC + MTX	1.49 (0.55,4.14)	1.24 (0.72,2.35)	0.09 (‐0.13,0.32)
Random‐Effect Model	Residual Deviance	212.5 vs 213 data points
	Deviance Information Criteria	1368.54
Fixed‐Effect Model	Residual Deviance	333.4 vs 213 data points
	Deviance Information Criteria	1449.97
Note:
Total Patients	30229
Total Studies	79
2‐arm	38
3‐arm	33
4‐arm	6
5‐arm	1
7‐arm	1