Cancer Analysis 4: Odds Ratios, Risk Ratios and Risk Difference for All Treatment Comparisons‐Random Effects Model
Treatment	Reference	OR (95% CrI)	RR (95% CrI)	RD % (95% Crl)
SD	PL	1.40 (0.63,3.00)	1.40 (0.63,2.96)	0.00 (0.00,0.01)
HD		1.35 (0.35,5.77)	1.35 (0.35,5.58)	0.00 (‐0.01,0.03)
LD		0.64 (0.13,2.33)	0.64 (0.13,2.31)	0.00 (‐0.01,0.01)
MTXSD		1.05 (0.65,1.71)	1.05 (0.65,1.70)	0.00 (0.00,0.00)
MTXLD		1.37 (0.42,4.05)	1.36 (0.43,3.97)	0.00 (‐0.01,0.02)
HD	SD	0.97 (0.22,4.53)	0.97 (0.23,4.40)	0.00 (‐0.01,0.03)
LD		0.46 (0.10,1.68)	0.46 (0.10,1.67)	‐0.01 (‐0.02,0.01)
MTXSD		0.75 (0.34,1.69)	0.75 (0.35,1.68)	0.00 (‐0.01,0.00)
MTXLD		0.98 (0.25,3.60)	0.98 (0.26,3.53)	0.00 (‐0.01,0.02)
LD	HD	0.47 (0.06,3.15)	0.47 (0.06,3.11)	‐0.01 (‐0.04,0.01)
MTXSD		0.79 (0.17,3.14)	0.79 (0.18,3.12)	0.00 (‐0.03,0.01)
MTXLD		1.02 (0.17,5.56)	1.02 (0.17,5.45)	0.00 (‐0.03,0.02)
MTXSD	LD	1.63 (0.42,8.73)	1.63 (0.43,8.65)	0.00 (‐0.01,0.01)
MTXLD		2.13 (0.39,14.46)	2.11 (0.39,14.17)	0.01 (‐0.01,0.03)
MTXLD	MTXSD	1.31 (0.40,3.77)	1.30 (0.40,3.69)	0.00 (‐0.01,0.02)
Random‐Effect Model	Residual Deviance	39.23 vs 51 data points
	Deviance Information Criteria	181.671
Fixed‐Effect Model	Residual Deviance	39.27 vs 51 data points
	Deviance Information Criteria	180.863
Note:
Total Patients	8740
Total Studies	22
2‐arm	15
3‐arm	7