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. 2020 Mar 12;20:202. doi: 10.1186/s12885-020-6687-9

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© The Author(s). 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Upregulated levels of NHERF1 expression were observed in ALK positive lung adenocarcinoma tissues. a Detection of NHERF1 protein by immunohistochemistry in tissue sections from ALK-translocated lung adenocarcinoma patients and compared to matched controls. b Quantification of (a) when n = 10 in both groups. c Relative NHERF1 mRNA levels in lung adenocarcinoma tissues (n = 226) from Set GSE31210 in the GEO database and the normal lung tissues (n = 20). d Stratified NHERF1 mRNA levels in ALK-translocated lung adenocarcinoma tissues (n = 11) and ALK negative samples (n = 215). *p < 0.05, **p < 0.01;***p < 0.001