Table 4.
Summary of measurements to be taken
| Domain | Data collection instrument | Time points | ||
|---|---|---|---|---|
| Baseline | 6 M | 12 M | ||
| Descriptive data | ||||
| Age, gender, height, body mass index | ✓ | |||
| Duration of knee OA symptoms | ✓ | |||
| Previous treatments and surgery | ✓ | |||
| Problems in other joints | ✓ | |||
| Medical history | ✓ | |||
| Expectation of treatment outcome | 5-point ordinal scale | ✓ | ||
| Primary outcome measures | ||||
| Average knee pain in past week | 11-point NRS | ✓ | ✓ | ✓ |
| Physical function in past 48 h | WOMAC physical function subscale | ✓ | ✓ | ✓ |
| Secondary outcome measures | ||||
| Weight | Self-reported | ✓ | ✓ | ✓ |
| Physical activity | IPEQ-W questionnaire | ✓ | ✓ | ✓ |
| Health-related quality of life | AQoL-8D questionnaire | ✓ | ✓ | ✓ |
| Perceived change since baseline | Overall change, 7-point ordinal scale | ✓ | ✓ | |
| Change in pain, 7-point ordinal scale | ✓ | ✓ | ||
| Change in function, 7-point ordinal scale | ✓ | ✓ | ||
| Change in physical activity, 7-point ordinal scale | ✓ | ✓ | ||
| Satisfaction with care | 7-point ordinal scale | ✓ | ✓ | |
| Appointment with orthopaedic surgeon | Yes/No | ✓ | ✓ | ✓ |
| Depression, anxiety, and stress | DASS-21 | ✓ | ✓ | ✓ |
| Surgery performed | Self-reported TKJR and arthroscopy | ✓ | ✓ | |
| Willingness to undergo surgery | 5-point ordinal scale | ✓ | ✓ | ✓ |
| Other measures | ||||
| Health economic data | Quality adjusted life years | ✓ | ✓ | ✓ |
| Self-reported medication use | ✓ | ✓ | ✓ | |
| Self-reported use of health services/co-interventions | ✓ | ✓ | ✓ | |
| Cost-effectiveness ratio | ✓ | ✓ | ||
| Work productivity (WHO HPQ Short Form) | ✓ | ✓ | ✓ | |
| Adherence | Number of consultations with physiotherapista | ✓ | ||
| Number of consultations with dietitianb | ✓ | |||
| Duration of consultations with physiotherapista | ✓ | |||
| Duration of consultations with dietitianb | ✓ | |||
| Self-rated adherence to strengthening exercisea/ physical activitya/weight managementb, 11-point NRS | ✓ | |||
| Perceived usefulness | Times accessed website, 5-point ordinal scale | ✓ | ✓ | |
| Usefulness of website, 11-point NRS | ✓ | |||
| Usefulness of physiotherapy consultationsa 11-point NRS | ✓ | |||
| Usefulness of dietitian consultationsb 11-point NRS | ✓ | |||
| Usefulness of educational resourcesa 11-point NRS | ✓ | |||
| Usefulness of Fitbita 11-point NRS | ✓ | |||
| Usefulness of ketogenic dietb 11-point NRS | ✓ | |||
| Usefulness of strengthening exercise programa 11-point NRS | ✓ | |||
| Usefulness of physical activity plana 11-point NRS | ✓ | |||
| Video software ease of usea 11-point NRS | ✓ | |||
| Harms | Adverse events | ✓ | ✓ | |
| Determinants | Self-efficacy for symptom control (ASES) | ✓ | ✓ | ✓ |
| Self-efficacy for eating (WELQ) | ✓ | ✓ | ✓ | |
| Attitudes towards self-management (PAM-13) | ✓ | ✓ | ✓ | |
| Treatment beliefs about arthroplasty (TOA) | ✓ | ✓ | ✓ | |
| Fear of movement (BFMS) | ✓ | ✓ | ✓ | |
| Long-term surgical rates | Number who have had arthroscopy/arthroplasty | 24 months and 60 months | ||
NRS Numeric rating scale, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, IPEQ-W Incidental and Planned Exercise Questionnaire, AQoL-8D Assessment of Quality of Life Instrument, DASS Depression, Anxiety, and Stress Scale, TKJR Total knee joint replacement, WHO HPQ World Health Organization Health and Work Performance Questionnaire, ASES Arthritis Self-efficacy Scale, WELQ Weight Efficacy Lifestyle Questionnaire, PAM Patient Activation Measure, TOA Treatment beliefs in knee and hip OA – arthroplasty subscale, BFMS Brief Fear of Movement Scale for osteoarthritis
ameasured in Exercise and Exercise plus weight management groups only
bmeasured in Exercise plus weight management group only