. 2020 Mar 13;20:58. doi: 10.1186/s12874-020-00926-y

Table 3.

PRISM Patient-Preferred Message Concepts

Message Concept	Example Copy	Theme Targeted
Infographic – Study Criteria	You may qualify if: 1) you have been diagnosed with autoimmune PAP¹, and: 2) are willing to travel to one of our clinical sites 3 times over a 2-year period.	Preference for high-contrast, graphic designs that summarize study eligibility criteria in easy-to-understand terms
Photographed Image – Emotional Appeal	PTEN hamartoma tumor syndrome is a genetic condition in which non-cancerous growths, called hamartomas, develop in different areas of the body. The disease is hereditary, which means it can be passed from parents to their children.	Patients want to feel emotionally connected to images they see featured in the recruitment post; use of family or group images preferred
Educational Post	People affected by PCT² generally experience “photosensitivity,” which causes painful, blistering lesions to develop on sun-exposed areas of the skin (i.e. the hands and face). RDCRN is NOW RECRUITING patients with PCT.	Includes more information about the rare disease that participants can easily share with friends or family to help them understand their diagnosis

Message Concept

Example Copy

Theme Targeted

Infographic – Study Criteria

You may qualify if: 1) you have been diagnosed with autoimmune PAP¹, and: 2) are willing to travel to one of our clinical sites 3 times over a 2-year period.

Preference for high-contrast, graphic designs that summarize study eligibility criteria in easy-to-understand terms

Photographed Image – Emotional Appeal

PTEN hamartoma tumor syndrome is a genetic condition in which non-cancerous growths, called hamartomas, develop in different areas of the body. The disease is hereditary, which means it can be passed from parents to their children.

Patients want to feel emotionally connected to images they see featured in the recruitment post; use of family or group images preferred

Educational Post

People affected by PCT² generally experience “photosensitivity,” which causes painful, blistering lesions to develop on sun-exposed areas of the skin (i.e. the hands and face).

RDCRN is NOW RECRUITING patients with PCT.

Includes more information about the rare disease that participants can easily share with friends or family to help them understand their diagnosis

¹Pulmonary alveolar proteinosis

²Porphyria cutanea tarda