Table 3.

The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of endometriosis-associated genes that coincided with Chinese herbs.

KEGG class	Pathway	out	All	Pvalue
Cancers	Pathways in cancer	64	550	6.88E-36
Endocrine and metabolic diseases	AGE-RAGE signaling pathway in diabetic complications	28	114	2.14E-24
Signal transduction	PI3K-Akt signaling pathway	42	374	3.13E-22
Signal transduction	HIF-1 signaling pathway	25	102	8.08E-22
Drug resistance	EGFR tyrosine kinase inhibitor resistance	23	82	1.32E-21
Drug resistance	Endocrine resistance	25	116	2.48E-20
Signal transduction	FoxO signaling pathway	26	139	1.84E-19
Cancers	MicroRNAs in cancer	27	168	2.15E-18
Immune system	IL-17 signaling pathway	22	106	1.30E-17
Signal transduction	TNF signaling pathway	23	130	9.72E-17
Signal transduction	MAPK signaling pathway	33	332	7.65E-16
Cell growth and death	Apoptosis	23	153	4.02E-15
Cellular community - eukaryotes	Focal adhesion	26	212	8.70E-15
Endocrine system	Prolactin signaling pathway	16	74	2.22E-13
Immune system	Toll-like receptor signaling pathway	19	122	6.04E-13
Signal transduction	Ras signaling pathway	25	243	1.73E-12
Immune system	T cell receptor signaling pathway	18	114	2.00E-12
Cell growth and death	p53 signaling pathway	15	73	2.86E-12
Signal transduction	ErbB signaling pathway	15	87	4.15E-11
Nervous system	Neurotrophin signaling pathway	17	124	8.75E-11
Immune system	Th17 cell differentiation	20	186	1.58E-10
Cell growth and death	Apoptosis - multiple species	10	33	2.19E-10
Endocrine system	Estrogen signaling pathway	19	171	2.66E-10
Signal transduction	VEGF signaling pathway	12	61	8.10E-10
Signal transduction	Rap1 signaling pathway	20	211	1.51E-09
Signal transduction	Jak-STAT signaling pathway	17	167	9.50E-09
Signal transduction	NF-kappa B signaling pathway	14	127	7.55E-08
Immune system	B cell receptor signaling pathway	11	74	9.07E-08
Endocrine system	GnRH signaling pathway	11	96	1.35E-06
Signal transduction	TGF-beta signaling pathway	7	92	0.001496753