Table 5.

The results of Connectivity Map (CMap) analysis.

Compounds name	Major source	mean	n	enrichment	P-value	specificity	Potential targets
A: CMap analysis of DEGs of ectopic endometrium vs. eutopic endometrium in patients with endometriosis.
genistein	Pueraria montana var. lobata (Willd.) Maesen & S.M.Almeida ex Sanjappa & Predeep(Gegenhua)	−0.356	17	−0.527	0.00006	0	ESR1,PPARG,PTGS2,MAPK14,HSP90AB1,CDK13,CHEK1,PRKACA,PRSS1,PIK3CG,NFKB3,EGFR,AKT1,VEGFA,BCL2,FOS,CDKN3,BAX,CASP9,MMP9,MAPK3,MAPK1,TNF,JUN,NOS2,AHSA1,CASP3,TP53,LRP5,MDM2,RASGRF1,RAF1,HIF1A,IGF1R,STAT1,CRK2,ERBB2,AR,PPARG,ICAM1,IL-1beta,CCL13,SELE,VCAM1,FN1,CXCL8,SOD2,BIRC5,NOS3,TGFB1,SULT1E1,CCNB1,PTEN,HMGCR,BTK,CHEK2,PPARA,PCOLCE
vinblastine	Catharanthus roseus (L.) G.Don [Apocynaceae], (Changchunhua)	−0.815	3	−0.932	0.0005	0.0153	ABCB1,JUN,ABCB4,TUBA1A,TUBB4B,ABCC2,TUBB,ABCG2,TUBE1,TUBD1
atractyloside	Xanthium strumarium subsp. strumarium (Cangerzi)	−0.432	5	−0.661	0.01071	0.0758	ANO6,VDAC1,CFD,PDLIM5,SLC25A4,SLC25A5
naringenin	Typha angustifolia L. [Typhaceae] (Puhuang), Curcuma aromatica Salisb./Curcuma longa L.(Yujin)	−0.341	4	−0.668	0.02733	0.1129	PPARA,ABCB1,CYP1A2,APOB,CYP1B1,CCL2,HMOX1,RAPGEF1,BDNF,LDLR
B: CMap analysis of DEGs of eutopic endometrium in patients vs. eutopic endometrium in healthy women.
canadine	Coptis teeta Wall. [Ranunculaceae] (Huanglian),Corydalis yanhusuo (Yanhusuo)	−0.633	4	−0.797	0.00334	0.0201	F3,DRD1
ursolic acid	Salvia miltiorrhiza Bung (Danshen)	−0.475	4	−0.735	0.00985	0.0146	PLAU,CTSB,VEGFA,BCL2,MMP2,TNF,JUN,IL6,TP53,MAPK8,PTGS2,FASN,MMP1,MMP3,MMP10,IL-1beta,SELE,PTGER3,PTGS1
lycorine	Curculigo orchioides Gaertn. [Hypoxidaceae] (Xianmao)	−0.404	5	−0.621	0.02055	0.2267	CHRM3,CHRM1,ADRB1,CHRM5,CHRM4,OPRD1,CHRM2,ADRA2B,ADRA1B,ADRB2,OPRM1
naringenin	Typha angustifolia L. [Typhaceae] (Puhuang), Curcuma aromatica Salisb./Curcuma longa L. (Yujin)	−0.34	4	−0.658	0.03133	0.121	PPARA,ABCB1,CYP1A2,APOB,CYP1B1,CCL2,HMOX1,RAPGEF1,BDNF,LDLR