Table 1.

Correlation between HOXC10 expression and clinicopathological characteristics of HCCs in two independent cohorts of human HCC tissues

Clinicopathological variables	Cohort I				Cohort II
	Tumor HOXC10 expression			P Value	Tumor HOXC10 expression		P Value
	Negative (n=239)		Positive (n=158)		Negative (n=188)	Positive (n=137)
Age ≤50		91	67	0.388	39	25	0.576
>50		148	91		149	112
Sex	female	56	29	0.227	31	16	0.223
	male	183	129		157	121
Serum AFP	≤20ng/ml	182	116	0.538	57	40	0.827
	>20ng/ml	57	42		131	97
Virus infection	HBV	172	110	0.741	131	101	0.761
	HCV	21	13		16	8
	HBV+HCV	13	7		12	7
	None	33	28		29	21
Cirrrhosis	absent	64	53	0.148	46	32	0.817
	present	175	105		142	105
Child-pugh score	Class A	184	122	0.958	153	109	0.682
	Class B	55	36		35	28
Tumor number	single	199	115	0.01	139	89	0.081
	multiple	40	43		49	48
Maximal tumor size	≤5cm	151	62	<0.001*	97	48	0.003
	>5cm	88	96		91	89
Tumor encapsulation	absent	110	51	0.006	60	64	0.007
	present	129	107		128	73
Microvascular invasion	absent	138	67	0.003	115	79	0.525
	present	101	91		73	58
Tumor differentiation	I-II	157	108	0.581	137	91	0.210
	III-IV	82	50		51	46
TNM stage	I-II	173	77	<0.001*	142	84	0.006
	III	66	81		46	53