Figure 9.

A. TEM of PEGylated FVIOs (top) and SAR comparison of PEGylated FVIOs and SPIONs at different fields (bottom). B. Schematic illustration of the experimental design and photographs of mice after treatments. C. FVIO-mediated mild magnetic hyperthermia therapy plus immune checkpoint therapy activates the antitumor immune response (left) and representative multispectral fluorescence images of distant tumors after immunofluorescence staining (right, scale bar = 100 μm). Reproduced with permission from ref 113. Copyright 2019 American Chemical Society.