Table 1.

Sequence of peptides used in this research.

Peptides	Sequence (N-C)
PRTC	IYP (OH) AL-AHX-KDVLSEKEKKLEEYKQKLARV-RRRRK
PRTC-m	IYP (OH) AL-AHX-KDVPSEKEKKPEEYKQKPARV-RRRRK
PRTC-v	KDVLSEKEKKLEEYKQKLARV-RRRRK
PRTC-r	IYP (OH) AL-AHX-KDVLSEKEKKLEEYKQKLARV
FITC-PRTC	FITC-AHX-IYP (OH) AL-AHX-KDVLSEKEKKLEEYKQKLARV-RRRRK
FITC-PRTC-m	FITC-AHX-IYP (OH) AL-AHX-KDVPSEKEKKPEEYKQKPARV-RRRRK
FITC-PRTC-v	FITC-AHX-KDVLSEKEKKLEEYKQKLARV-RRRRK
FITC-PRTC-r	FITC-AHX-IYP (OH) AL-AHX-KDVLSEKEKKLEEYKQKLARV
CL (CREPT Ligand )	KDVLSEKEKKLEEYKQKLARV
CL-m (CREPT Ligand-m)	KDVPSEKEKKPEEYKQKPARV
VHL Ligand	IYP (OH) AL
Transmembrane transport peptide	RRRRK

For the peptides, the blue part was the sequence targeting CREPT. The black part was the linker group. The purple part was the sequence binding VHL E3 ubiquitin ligase. The orange part was the sequence permeating cell membrane. For flow cytometry and fluorescence assays, fluorescein isothiocyanate (FITC) was labeled at the N-terminus with a AHX linker. AHX, 6-aminohexanoic acid. P(OH), trans-4-hydroxy-L-proline.