Table 1.

List of outcome measures

Measure	Measured by	Objectives
MPF biology
- Placental corticotropin-releasing hormone (CRH)  - Interleukin (IL)-6,  - C-reactive protein (CRP)  - Cortisol	- Blood and saliva sample during pregnancy at T1 and T2	To measure and analyse differences in endocrine and immune stress markers during pregnancy
Birth and developmental outcomes
- Birth weight & length  - Birth outcomes (delivery, complications)  - Length of gestation	- Abstraction of medical data from obstetric record at birth
- Current weight & length  - Chronic disease  - Physical disabilities  - Mental disabilities  - Neurodevelopmental disorders	- Abstraction of medical data from obstetric and child examination records at birth and during routine child health examinations (“U-Untersuchungen”) in first month of life	To measure birth and infant anthropometric and developmental outcomes and their association with mothers MPF biology during pregnancy
- Reported developmental physical impairments  - Reported neurodevelopmental disorders	- Reported by mother at T3