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. Author manuscript; available in PMC: 2020 Mar 13.
Published in final edited form as: Cell Rep. 2020 Jan 28;30(4):1235–1245.e4. doi: 10.1016/j.celrep.2019.12.067

Figure 3. Detection of Nonenzymatic DPCs by the ARK Assay.

Figure 3.

(A) Dose response of 293A, HeLa, and TK6 cells exposed to the indicated concentrations of FA for 2 h. DPC fold inductions were calculated by normalizing DPC-associated DNA to that of mock treatment.

(B) DPC repair time course in 293A, HeLa, and TK6 cells exposed to 400 μM FA treatment for 2 h. DPC coefficient of each cell line after treatment is set as 100%.

n = 4 for (A) and n = 6 for (B). The error bars depict standard deviations.