Table 1.

Use* of TdP risk classified drugs at the event of TdP, in relation to therapeutic group and TdP risk class (acid-secretion drugs and diuretics with TdP 3 risk classification but not blocking the hERG channel excluded), expressed as number of TdP cases when a certain drug was used* during the study period 2006–2017

Antidepressant drugs		Antipsychotic drugs		Antinfective drugs		Cardiovascular drugs		Drugs in other groups		Total
TdP 1		TdP 1		TdP 1		TdP 1		TdP 1		175
Citalopram	72	Haloperidol	3	Ciprofloxacin	4	Amiodarone	19	Donepezil	7
Escitalopram	5	Levomepromazine	2	Fluconazole	2	Dronedarone	3	Methadone	4
				Moxifloxacin	2	Disopyramide	9	Papaverine	2
				Erytromycin	1	Flecainide	3
						Sotalol	37
TdP 2		TdP 2		TdP 2		TdP 2		TdP 2		80
Mirtazapine	28	Olanzapine	9					Alfuzosin	13
Clomipramine	5	Aripiprazole	1					Tolterodine	5
Venlafaxine	2	Clozapine	1					Solifenacin	3
		Litium	1					Memantine	3
		Perphenazine	1					Buprenorphine	2
		Risperidone	1					Promethazine	2
								Tacrolimus	2
								Tamoxifen	1
TdP 3		TdP 3		TdP 3		TdP 3		TdP 3		66
Sertraline	14	Quetiapine	3	Posaconazole	1	Isradipine	3	Hydroxizine	20
Amitriptylin	5			Metronidazole	1			Metoclopramide	6
Fluoxetine	3							Loperamide	5
Paroxetine	2							Hydroxychloroquine	3
Total	136		22		11		74		78	321

*A person is considered to have used a drug if the person has a dispensed prescription lasting until or beyond the TdP event day. See the Methods section for details.

TdP, torsades de pointes.